Protein Alignment nec and Serpinf1

DIOPT Version :10

• Sequence 1: NP_524851.1
• Gene: nec / 45908
• FlyBaseID: FBgn0002930
• Length: 476
• Species: Drosophila melanogaster
• Sequence 2: NP_035470.3
• Gene: Serpinf1 / 20317
• MGIID: 108080
• Length: 417
• Species: Mus musculus
• Alignment Length: 449
• Identity: 106/449 - (23%)
• Similarity: 192/449 - (42%)
• Gaps: 89/449 - (19%)

  Fly    71 WT--------QNNQEAISDVVAVDLTKREPVTP-------PPNRPPPVFSYMDRFSSELFKEIIK 120
            ||        ..|..:.|:...|..:..|||..       |.|:   :.:.:..|..:|::....
Mouse     9 WTGALLGHGSSQNVPSSSEGSPVPDSTGEPVEEEDPFFKVPVNK---LAAAVSNFGYDLYRLRSS 70

  Fly   121 SQSQQNVVFSPFSV-HALLALIYGASDGKTFRELQKAGEFSKNAMAVAQDFESVIKYKKHLEGA- 183
            :....||:.||.|| .||.||..|| :.:|...:.:|..:.   :....|..|.  ||:.|...
Mouse    71 ASPTGNVLLSPLSVATALSALSLGA-EHRTESVIHRALYYD---LITNPDIHST--YKELLASVT 129

  Fly   184 ----DLTLATKVYYNREL-------GGVNHSYDEYAKFYFSAGTEAVDMQNAKDTAAKINAWVMD 237
                :|..|:::.:.|:|       ..:..||....:..  .|...||:|       :||.||..
Mouse   130 APEKNLKSASRIVFERKLRVKSSFVAPLEKSYGTRPRIL--TGNPRVDLQ-------EINNWVQA 185

  Fly   238 TTRNKI----RDLVTPTDVDPQTQALLVNAVYFQGRWEHEFATMDTSPYDFQHTNGRISKVAMMF 298
            ..:.||    |::.:...:      ||:...||:|:|..:|.:..|:..||.....|..:|.||.
Mouse   186 QMKGKIARSTREMPSALSI------LLLGVAYFKGQWVTKFDSRKTTLQDFHLDEDRTVRVPMMS 244

  Fly   299 NDDV---YGL--------AELPELGATALELAYKDSATSMLILLPNETTGLGKMLQQLSRPEF-- 350
            :...   |||        |:||..|           :.|::..||...|....|:::....||
Mouse   245 DPKAILRYGLDSDLNCKIAQLPLTG-----------SMSIIFFLPLTVTQNLTMIEESLTSEFIH 298

  Fly   351 DLNRVAHRLRRQSVAVRLPKFQFEFEQDMTEPLKNLGVHQMFTPNSQVTKLMDQPVRVSKILQKA 415
            |::|   .|:.....:.:||.:..||.::|:.|:::.:..:| .:...:|:..:||:::::..:|
Mouse   299 DIDR---ELKTIQAVLTVPKLKLSFEGELTKSLQDMKLQSLF-ESPDFSKITGKPVKLTQVEHRA 359

  Fly   416 YINVGEAGTEASAASYAKFVPLSLPPKPTEFVANRPFVFAVR--TPASVLFIGHVEYPT 472
            .....|.|..:|.:...:.|.|:.   |.::..|:||:|.:|  ...::||||.:..|:
Mouse   360 AFEWNEEGAGSSPSPGLQPVRLTF---PLDYHLNQPFLFVLRDTDTGALLFIGRILDPS 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nec	NP_524851.1	serpin42Dd-like_insects	105..471	CDD:381070	95/397 (24%)
Serpinf1	NP_035470.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	17..41		6/23 (26%)
		serpinF1_PEDF	40..412	CDD:381008	97/413 (23%)