Protein Alignment cpo and WHI3

DIOPT Version :10

• Sequence 1: NP_001014632.3
• Gene: cpo / 45840
• FlyBaseID: FBgn0263995
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_014202.1
• Gene: WHI3 / 855524
• SGDID: S000005141
• Length: 661
• Species: Saccharomyces cerevisiae
• Alignment Length: 876
• Identity: 165/876 - (18%)
• Similarity: 285/876 - (32%)
• Gaps: 338/876 - (38%)

  Fly     4 SHHQLLIAATAA----AAAAAAAEPQLQLQHLLPAAPTTPAVISNPIN--SIGPINQISSSSHPS 62
            ||...|...|.:    |:...:|..:|.|..     ..:|..||:.:|  ::|.:.|..:||:.|
Yeast    33 SHRSSLNLNTTSHPHEASGRGSASGELYLND-----TNSPLAISSMLNTLALGSMPQDIASSNIS 92

  Fly    63 NNNQQ----------------------AVFEKAITISSIAIKRRPTLPQTPASAPQVLSPSPKRQ 105
            |::..                      |:|..|..:.||.::::       .|:..:.|.|.:.:
Yeast    93 NHDNNIKGSYSLKLSNVAKDITLRECYAIFALAEGVKSIELQKK-------NSSSSITSASLEDE 150

  Fly   106 ----CAAAVSVLPVTVPVPVPV---------SVPLPVSVPVPVSVKGHPISHTHQ--IAHTHQIS 155
                ..|...:|.:.:...|.:         |.|...:|.:......:.:|....  ...|.:::
Yeast   151 NDIFIIARFELLNLAINYAVILNSKNELFGPSFPNKTTVEIIDDTTKNLVSFPSSAIFNDTSRLN 215

  Fly   156 HSH-----PISHPHHHQLSFAHPTQFAAAVAAHHQQQQQQQAQQ-QQQAVQQQQQQAVQQQQVAY 214
            .|:     |.......:.||:.|....:.::....||||||.|| ||.:.|:...|...||||..
Yeast   216 KSNSGMKRPSLLSQRSRFSFSDPFSNDSPLSQQQSQQQQQQPQQPQQHSTQKHSPQQCNQQQVNS 280

  Fly   215 AVAASPQLQQQQQQQQHRLAQFNQAAAAALLNQHLQQQHQAQQQQHQAQQQSLAHYGGYQLHRYA 279
            ::..|.|.|                    ::..|....||....:...|...:.
Yeast   281 SIPLSSQGQ--------------------VIGLHSNHSHQDLSVESTIQTSDIG----------- 314

  Fly   280 PQQQQQHILLSSGSSSSKHNSNNNSNTSAGAASAAVPIATSVAAVPTTGGSLPDSPAHESHSHES 344
                 :..||         ..|...|......|          .:|::......:|
Yeast   315 -----KSFLL---------RDNTEINEKIWGTS----------GIPSSINGYMSTP--------- 346

  Fly   345 NSATASAPTTPSPAGSVTSAAPTATATAAAAGSAAATAAATGTPATSAVSDSNNNLNSSSSSNSN 409
                  .|:||:.....|||:...::....  |||:||.|.....|||.:::::| |.:|::.:|
Yeast   347 ------QPSTPTLEWGNTSASQHGSSFFLP--SAASTAIAPTNSNTSANANASSN-NGASNNGAN 402

  Fly   410 SNAIMENQMALAPLGLSQSMDSVNTASNEEEVRTLFVSGLPMDAKPRELYLLFRAYEGYEGSLLK 474
            ......:|..:..:|     :::||:
Yeast   403 QALSASSQQPMMQIG-----NTINTS--------------------------------------- 423

  Fly   475 VTSKNGKTASPVGFVTFHTRAGAEAAKQDLQGVRFDPDM---PQTIRLEFAKSNTKVSKPKPQPN 536
            :||.|  :..|.|.::        :..|.:..:....||   ||       |.|..:.:|:|:
Yeast   424 LTSSN--SLPPYGLMS--------SQSQHISNMVNTSDMNITPQ-------KQNRFMQQPQPE-- 469

  Fly   537 TATTASHPALMHPLTGHLGGPFFPGGPELWHHPLAYSAAAAAELPGAAALQHATLVHPALHPQ-- 599
                  |   |:|                                          |:.:..||
Yeast   470 ------H---MYP------------------------------------------VNQSNTPQKV 483

  Fly   600 VPVRSYLXLNTDKVMEQPMHQTQMTMPPHHQTTAIHPGAAMAHMAAAAAAAAAGGGGGAATAAAA 664
            .|.|.....|:.|               ::.||::.....                 |:|:.:.|
Yeast   484 PPARLSSSRNSHK---------------NNSTTSLSSNIT-----------------GSASISQA 516

  Fly   665 PQSAAATAAAAAAASHHHYLSSPALASPAGSTNNASHPGNPQIAANAPCSTLFVANLGQFVSEHE 729
            ..|..|..              |..|:||..              |.||:||:|.||....:|.|
Yeast   517 DLSLLARI--------------PPPANPADQ--------------NPPCNTLYVGNLPSDATEQE 553

  Fly   730 LKEVFSSMPGFCRLRMHTKAMATATGSSCSTSNGSGSSSNSNHNSAAVQQHPVAFIEFKDPPTAS 794
            |:::||...||.||....|.         :||||        |:..     |:.|:||.|...|:
Yeast   554 LRQLFSGQEGFRRLSFRNKN---------TTSNG--------HSHG-----PMCFVEFDDVSFAT 596

  Fly   795 QAMQQLQGKYL---LSSDRGSIRIEFARSKM 822
            :|:.:|.|:.|   ..|.:|.||:.|:::.:
Yeast   597 RALAELYGRQLPRSTVSSKGGIRLSFSKNPL 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cpo	NP_001014632.3	RRM_cpo	441..523	CDD:410085	10/84 (12%)
		RRM_scw1_like	712..819	CDD:409691	37/109 (34%)
WHI3	NP_014202.1	dRRM_Rrp7p	510..>559	CDD:454777	19/76 (25%)
		RRM_scw1_like	536..624	CDD:409691	37/109 (34%)