Protein Alignment bel and DBP2

DIOPT Version :10

• Sequence 1: NP_001262379.1
• Gene: bel / 45826
• FlyBaseID: FBgn0263231
• Length: 801
• Species: Drosophila melanogaster
• Sequence 2: NP_014287.3
• Gene: DBP2 / 855611
• SGDID: S000005056
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 667
• Identity: 245/667 - (36%)
• Similarity: 350/667 - (52%)
• Gaps: 127/667 - (19%)

  Fly   107 GGRGFNRQSGDYGYGSGGGGRRGGGGRFEDNYNGGEFDSRRGGDWNRSGGGGGGGRGFGRGPSYR 171
            |||  ::|.....|.|.||..|||.....::||    |..:||                   :||
Yeast     4 GGR--DQQYNKTNYKSRGGDFRGGRNSDRNSYN----DRPQGG-------------------NYR 43

  Fly   172 GGGGGSGSNLNEQTAEDGQAQQQQQPRNDRWQE--PERPAGFDGSEGGQSAGGNRSYNNRGERGG 234
            ||.||. ||.|       |.|:..:|   .|.|  |:.|. |:           :::
Yeast    44 GGFGGR-SNYN-------QPQELIKP---NWDEELPKLPT-FE-----------KNF-------- 77

  Fly   235 GGYNSRWKEGGGSNVDYTKLGARDERLEVELFGVGNTGINFDKYEDIPVEATGQNVPPNITSFDD 299
                            |.:..:..:|.:.|:       ..|.|..::.:  :|.::|..||:||:
Yeast    78 ----------------YVEHESVRDRSDSEI-------AQFRKENEMTI--SGHDIPKPITTFDE 117

  Fly   300 VQLTEIIRNNVALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVP 364
            ....:.:.|.|....:||||.:|....|:.::|||::..|.||||||.::.:|.:..:.....:.
Yeast   118 AGFPDYVLNEVKAEGFDKPTGIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPGIVHINAQPLLA 182

  Fly   365 PPQSTRQYSRRKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGC 429
            |...          |:.||||||||||.||..|..||.:.||:|...:|||...|:|:|:|.||.
Yeast   183 PGDG----------PIVLVLAPTRELAVQIQTECSKFGHSSRIRNTCVYGGVPKSQQIRDLSRGS 237

  Fly   430 HLIVATPGRLEDMITRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFS 494
            .:::||||||.||:..||..|:.:.:|||||||||||||||||||:||:|:.    ..|||||:|
Yeast   238 EIVIATPGRLIDMLEIGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIR----PDRQTLMWS 298

  Fly   495 ATFPKQIQELASDFLSNYIFLAVGRVG-STSENITQTILWVYEPDKRSYLLDLLSSIRDGPEYTK 558
            ||:||::::||:|:|::.|.:.||.:. |.|.||||.:..|.:.:||..|...|.:.....||.
Yeast   299 ATWPKEVKQLAADYLNDPIQVQVGSLELSASHNITQIVEVVSDFEKRDRLNKYLETASQDNEYK- 362

  Fly   559 DSLTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGL 623
               ||||..||:..|.:.::|.:...|..:||||:.|:||:..|:.||:|..||:|||.|||||:
Yeast   363 ---TLIFASTKRMCDDITKYLREDGWPALAIHGDKDQRERDWVLQEFRNGRSPIMVATDVAARGI 424

  Fly   624 DIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQEIPSF 688
            |:..:.:|||:|:|.::|:||||||||||.|..|.|.|||.|:|:.:.:.|:.::.|..|.||.
Yeast   425 DVKGINYVINYDMPGNIEDYVHRIGRTGRAGATGTAISFFTEQNKGLGAKLISIMREANQNIPP- 488

  Fly   689 MEDMSSDRGHGGAKRAGRGGGGRYGGGFGSRDYRQSSGGGGGGRSGPPPRSGGSGSGGGGGSYRS 753
             |.:..||      |:..||..|||||.|.|        ||.||.|        |.|||.|.|..
Yeast   489 -ELLKYDR------RSYGGGHPRYGGGRGGR--------GGYGRRG--------GYGGGRGGYGG 530

  Fly   754 NGNSYGKFGGNSGGGGY 770
            |....|.: ||.|...|
Yeast   531 NRQRDGGW-GNRGRSNY 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc_DDX3	275..522	CDD:350809	106/247 (43%)
		SF2_C_DEAD	527..663	CDD:350174	61/135 (45%)
DBP2	NP_014287.3	DEAD-like_helicase_N	4..492	CDD:475120	216/588 (37%)