Protein Alignment bel and Ddx50

DIOPT Version :10

• Sequence 1: NP_001262379.1
• Gene: bel / 45826
• FlyBaseID: FBgn0263231
• Length: 801
• Species: Drosophila melanogaster
• Sequence 2: NP_001013216.2
• Gene: Ddx50 / 361848
• RGDID: 1310934
• Length: 734
• Species: Rattus norvegicus
• Alignment Length: 758
• Identity: 188/758 - (24%)
• Similarity: 289/758 - (38%)
• Gaps: 206/758 - (27%)

  Fly   183 EQTAEDGQAQQQQQPRNDRWQ---EPERPAGFDGSEGG----------QSAGGNRSYNNRGERG- 233
            |...|:.::|::::.:|||.:   ..|.....:..|.|          :.|......|...:.|
  Rat    14 EAPLEESESQRKERQKNDRRKSRHHSESEERTETRENGVTDDLDAPKPKKAKTREKLNGDTKEGL 78

  Fly   234 ------GGGYNSRWKEGGGSNVD-YTKLGARDERLEVELFGVGNTGINFDKYEDIPVEATGQNVP 291
                  ...:.||.|:....:|| |.|...|....|       |:..:.||.::.......:.
  Rat    79 RFSDEFSPSHKSRRKDLPNGDVDEYEKRSKRVSSSE-------NSHKSSDKADETLTREQKEG-- 134

  Fly   292 PNITSFDDVQLTEIIRNNVALARYDKPT---PVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPI 353
                :|.:..::|   ..:.|.:....|   |:|......:..|:||:|.|:||:|||.:|.:|:
  Rat   135 ----AFSNFSISE---ETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPL 192

  Fly   354 LNQMYELGHVPPPQSTRQYSRRKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNT 418
            :.::         |..::..::.:.|..||||||||||.|:.::.|...  .::..|..|||.:.
  Rat   193 IERL---------QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDIT--RKLNVACFYGGTSY 246

  Fly   419 SEQMRELDRGCHLIVATPGRLEDMITRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIV-EQLNM 482
            ..|:.::..|..::|.||||::|.:..|::.|..:|.:||||.|:|||:||..|:..|: |....
  Rat   247 QSQINQIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKS 311

  Fly   483 PPTGQRQTLMFSATFPKQIQELASDFLSNYIFLAVGRVGSTSENITQTI-------LWVYEPDKR 540
            ......|||:||||.|:.:.::|..::.:. :..|..||..::....|:       .|...|...
  Rat   312 DSEDNPQTLLFSATCPQWVYKVAKKYMKSR-YEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVI 375

  Fly   541 SYLLDLLSSIRDGPEYTKDSLTLIFVETKKGADSLEEFLY-----QCNHPVTSIHGDRTQKEREE 600
            ..:|.:.|.        .:...:||.||||....:....:     ||      :|||..|.:||.
  Rat   376 GDVLQVYSG--------SEGRAIIFCETKKNVTEMAMNPHIKQNAQC------LHGDIAQSQREI 426

  Fly   601 ALRCFRSGDCPILVATAVAARGLDIPHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFNE 665
            .|:.||.|...:||||.|||||||||.|..||....|.|||.|:||.|||||.|..|:...|:..
  Rat   427 TLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICVCFYQP 491

  Fly   666 KNRN-------------------ICSDLL--------------------------ELLIETK--- 682
            :.|.                   ...||:                          :.|||.|
  Rat   492 RERGQLRYVEQKAGITFKRVGVPSTMDLVKSKSMDAIRSLASVSYAAVDFFRPSAQRLIEEKGAV 556

  Fly   683 --------------------------------QEIPSFMEDMSSDRGHGGAKRAG---------- 705
                                            .|.|..::|:|........|.:.
  Rat   557 DALAAALAHISGASSFEPRSLITSDKGFVTMTLESPEEIQDVSCAWKELNRKLSSNAVSQVTRMC 621

  Fly   706 --RGGGG----------------------------------RYGGGFGSRDYRQSSGGGGGGRSG 734
              :|..|                                  .|..|..|.:.||.| |..|||||
  Rat   622 LLKGNMGVCFDVPTSESERLQAEWHDSDWILSVPAKLPEIEEYYDGNTSSNPRQRS-GWSGGRSG 685

  Fly   735 PPPRSGGSGSGGGGGSYRSNGNSYGKFGGNSGGGGYYGGGAGG 777
            ...||||...|..|...|....|..:..|....|......:||
  Rat   686 RSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRSGG 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc_DDX3	275..522	CDD:350809	73/250 (29%)
		SF2_C_DEAD	527..663	CDD:350174	53/147 (36%)
Ddx50	NP_001013216.2	SrmB	136..523	CDD:440279	129/415 (31%)
		GUCT_RHII_Gualpha_beta	565..656	CDD:240593	7/90 (8%)