Protein Alignment bel and Ddx5

DIOPT Version :10

• Sequence 1: NP_001262379.1
• Gene: bel / 45826
• FlyBaseID: FBgn0263231
• Length: 801
• Species: Drosophila melanogaster
• Sequence 2: NP_001007614.1
• Gene: Ddx5 / 287765
• RGDID: 619906
• Length: 615
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 208/610 - (34%)
• Similarity: 313/610 - (51%)
• Gaps: 90/610 - (14%)

  Fly   199 NDRWQEPERPAG---FDGSEGGQSAGGNRSYNNRGERGGGGYNSRWKEGGGSNVD---------- 250
            :||.:..:|..|   |.||..|..:|  :.:.|.||:   ....:|      |:|
  Rat     6 SDRDRGRDRGFGAPRFGGSRTGPLSG--KKFGNPGEK---LVKKKW------NLDELPKFEKNFY 59

  Fly   251 --YTKLGARDERLEVELFGVGNTGINFDKYEDIPVEATGQNVPPNITSFDDVQLTEIIRNNVALA 313
              :..| ||....||:         .:.:.::|.|.  |.|.|..:.:|.:......:.:.:|..
  Rat    60 QEHPDL-ARRTAQEVD---------TYRRSKEITVR--GHNCPKPVLNFYEANFPANVMDVIARQ 112

  Fly   314 RYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQSTRQYSRRKQY 378
            .:.:||.:|....|:.::|.|::..||||||||.::|:|.:   ..:.|.|       :..|...
  Rat   113 NFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAI---VHINHQP-------FLERGDG 167

  Fly   379 PLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRLEDMI 443
            |:.||||||||||.|:.:.|.::....|::...:|||.....|:|:|:||..:.:||||||.|.:
  Rat   168 PICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFL 232

  Fly   444 TRGKVGLENIRFLVLDEADRMLDMGFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQELASDF 508
            ..||..|....:|||||||||||||||||||:||:|:.    ..|||||:|||:||::::||.||
  Rat   233 ECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIR----PDRQTLMWSATWPKEVRQLAEDF 293

  Fly   509 LSNYIFLAVGRVG-STSENITQTILWVYEPDKRSYLLDLLSSIRDGPEYTKDSLTLIFVETKKGA 572
            |.:||.:.:|.:. |.:.||.|.:...::.:|...|:.|:..|..    .|::.|::|||||:..
  Rat   294 LKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMS----EKENKTIVFVETKRRC 354

  Fly   573 DSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGLDIPHVKHVINFDLP 637
            |.|...:.:...|...||||::|:||:..|..|:.|..|||:||.||:||||:..||.|||:|.|
  Rat   355 DELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYP 419

  Fly   638 SDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQEIPSFMEDMSSDRGHGGAK 702
            :..|:|:||||||.|....|.|.:||...|....|||:.:|.|..|.|...:..:..|||.|.::
  Rat   420 NSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSR 484

  Fly   703 RAGRGGGGRYGGGFGSRDYRQSSGGGGGGRSGPPPRSGGSGSGGGGGSYRSNGN---SYGK---- 760
              |||         |.:|.|:.              ...:|..||..::|...|   .|..
  Rat   485 --GRG---------GMKDDRRD--------------RYSAGKRGGFNTFRDRENYDRGYSSLLKR 524

  Fly   761 -FGGNSGGGGYYGGGAGGGSYGGSY 784
             ||..:..|.|.......||:|.::
  Rat   525 DFGAKTQNGVYSAANYTNGSFGSNF 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc_DDX3	275..522	CDD:350809	98/247 (40%)
		SF2_C_DEAD	527..663	CDD:350174	55/135 (41%)
Ddx5	NP_001007614.1	DEAD-like_helicase_N	6..507	CDD:475120	198/566 (35%)
		P68HR	498..532	CDD:429808	8/33 (24%)
		P68HR	551..583	CDD:429808