Protein Alignment bel and glh-1

DIOPT Version :10

• Sequence 1: NP_001262379.1
• Gene: bel / 45826
• FlyBaseID: FBgn0263231
• Length: 801
• Species: Drosophila melanogaster
• Sequence 2: NP_491963.1
• Gene: glh-1 / 172414
• WormBaseID: WBGene00001598
• Length: 763
• Species: Caenorhabditis elegans
• Alignment Length: 809
• Identity: 272/809 - (33%)
• Similarity: 389/809 - (48%)
• Gaps: 170/809 - (21%)

  Fly    21 LNGGSADYSGPITSKTSTNSVTGGVYVPPHLRGGGGNNNAADAESQGQGQGQGQGFDSRSGNPRQ 85
            ::.|.:|......:||...|  ||.:       |||||..:   ..|.|:..|.||.  .||.
 Worm     1 MSDGWSDSESAAKAKTGFGS--GGGF-------GGGNNGGS---GFGGGKNGGTGFG--GGNT-- 49

  Fly    86 ETRDPQQSRGGGGEYRRGGGGGGRGF-NRQSGDYGYGSG-------GGGRRG-----------GG 131
                       ||....||..||.|| ..::|..|:|.|       |||..|           ||
 Worm    50 -----------GGSGFGGGNTGGSGFGGGKTGGSGFGGGNTCGSGFGGGSTGGSPYGGASSGFGG 103

  Fly   132 GRFEDNYNGGEFDSRRGGDWNRSGGGGGGGRGFGRGPSYRGGG---------GGSGSNLN----- 182
            ......:..||..|..||    |||.||...|||.|....|||         ||...|.|
 Worm   104 STATSGFGSGEKSSAFGG----SGGFGGSATGFGSGGGSFGGGNSGFGEGGHGGGERNNNCFNCQ 164

  Fly   183 ---EQTAEDGQAQQQQQPR----------------NDRWQEPERPAGFDGSEGGQSAGGNRSYNN 228
               .::::..:.:::::||                .:|.....|..||.|..|..:.|||..:..
 Worm   165 QPGHRSSDCPEPRKEREPRVCYNCQQPGHTSRECTEERKPREGRTGGFGGGAGFGNNGGNDGFGG 229

  Fly   229 RGERGGG----------------------------------GYNS----------RWKEGGGSNV 249
            .|..|||                                  |:.|          ...||.|...
 Worm   230 DGGFGGGEERGPMKCFNCKGEGHRSAECPEPPRGCFNCGEQGHRSNECPNPAKPREGVEGEGPKA 294

  Fly   250 DYTKLGARDERLEVELFGVG--NTGINFDKYEDIPVEATGQNVPPNI---TSFDDVQLTEIIRNN 309
            .|..:   ::.:| ::|.:.  :.|:.|:|:.|..|:.|.......|   .:|.:..|||.::.|
 Worm   295 TYVPV---EDNME-DVFNMQKISEGLMFNKFFDAEVKLTSSEKTVGIKPCKTFAEANLTETMQKN 355

  Fly   310 VALARYDKPTPVQKHAIPIIINGRDLMACAQTGSGKTAAFLVPILNQMYELGHVPPPQSTRQYSR 374
            ||.|.|.|.||:|::|:|::..|.|:|||||||||||||||:||:.::.:      ..:......
 Worm   356 VAHAGYSKTTPIQQYALPLVHQGYDIMACAQTGSGKTAAFLLPIMTRLID------DNNLNTAGE 414

  Fly   375 RKQYPLGLVLAPTRELATQIFEEAKKFAYRSRMRPAVLYGGNNTSEQMRELDRGCHLIVATPGRL 439
            ...||..::|.||||||.||:.|.:||||::.|....:|||........::::|..:||.|.||:
 Worm   415 GGCYPRCIILTPTRELADQIYNEGRKFAYQTMMEIKPVYGGLAVGYNKGQIEKGATIIVGTVGRI 479

  Fly   440 EDMITRGKVGLENIRFLVLDEADRMLD-MGFEPQIRRIVEQLNMPPTGQRQTLMFSATFPKQIQE 503
            :.....|.:.|:..||.||||||||:| |||...|..||...:||....|||||||||||..:||
 Worm   480 KHFCEEGTIKLDKCRFFVLDEADRMIDAMGFGTDIETIVNYDSMPRKENRQTLMFSATFPDSVQE 544

  Fly   504 LASDFL-SNYIFLAVGRVGSTSENITQTILWVYEPDKRSYLLDLL-------SSIRDGPEYTKDS 560
            .|..|| .||:.:|:.::|:.::.:.|........:|:..||:||       ::.:....|||.
 Worm   545 AARAFLRENYVMIAIDKIGAANKCVLQEFERCERSEKKDKLLELLGIDIDSYTTEKSAEVYTKK- 608

  Fly   561 LTLIFVETKKGADSLEEFLYQCNHPVTSIHGDRTQKEREEALRCFRSGDCPILVATAVAARGLDI 625
             |::||..:..||:|...|.....|..:|||.|.|:||.||||.||:|..|:|:|||||.|||||
 Worm   609 -TMVFVSQRAMADTLASILSSAQVPAITIHGAREQRERSEALRQFRNGSKPVLIATAVAERGLDI 672

  Fly   626 PHVKHVINFDLPSDVEEYVHRIGRTGRMGNLGVATSFFNEKNRNICSDLLELLIETKQEIPSFME 690
            ..|.||||:|:|.::::|:||||||||:||.|.||||.:| :.::.|:|:.:|.:.:|.:|.:|:
 Worm   673 KGVDHVINYDMPDNIDDYIHRIGRTGRVGNSGRATSFISE-DCSLLSELVGVLADAQQIVPDWMQ 736

  Fly   691 DMSSDRGHGGAKRAGRGGGGRYG-GGFGS 718
                     ||      .||.|| .||||
 Worm   737 ---------GA------AGGNYGASGFGS 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bel	NP_001262379.1	DEADc_DDX3	275..522	CDD:350809	106/251 (42%)
		SF2_C_DEAD	527..663	CDD:350174	65/142 (46%)
glh-1	NP_491963.1	PTZ00368	<160..278	CDD:173561	17/117 (15%)
		SrmB	342..713	CDD:440279	168/379 (44%)