Protein Alignment Spn27A and SERPINA11

DIOPT Version :10

• Sequence 1: NP_652024.1
• Gene: Spn27A / 45815
• FlyBaseID: FBgn0028990
• Length: 447
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 92/391 - (23%)
• Similarity: 174/391 - (44%)
• Gaps: 51/391 - (13%)

  Fly    76 FSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAGTQTQV------ELANTQTDIRSQNN 134
            |:..|.|.:..:  |..|:..||.|:...||||:..|.|.|...:      .|..|     .:.:
Human    57 FALRLYKELAAD--APGNIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTET-----PEAD 114

  Fly   135 VREFYRKTLNSFKKENQLHETLSVRTKLFTDSFIETQQKFTATLKHFYDSEVEALDFTNPEAAAD 199
            :.:.:|..|::....:...| |.|...||.|..::.:|.:..::|..|.:...:.:||:......
Human   115 IHQGFRSLLHTLALPSPKLE-LKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGR 178

  Fly   200 AINAWAANITQGRLQQLVAPDNVRSSVMLLTNLIYFNGLWRRQFA---TTFQGSFFRSKDDQSRA 261
            .||.:....|.|::...: |:..:.:.|:|.|.|:|...|:..|:   |..|.|||..:....:.
Human   179 QINDYLRRQTYGQVVDCL-PEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQV 242

  Fly   262 EFMEQTDYFYYTTSEKLKAQILRLPYKGKNSLFVLLPYALNGIHDLVKNLENDELKSAQWAMEEV 326
            ..|.|.:...:...:.|...:|::.|:|.....::||             :..::|..:.|::..
Human   243 PMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLP-------------DPGKMKQVEAALQPQ 294

  Fly   327 KVK------------VTLPKFHFDYQQNLKETLRSLGVREIFEDSASLPGLTRGADVAGKVK--V 377
            .::            :.||:|......||::.|..:|:..|....|...|:|      |::.  :
Human   295 TLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVT------GQLNKTI 353

  Fly   378 SNILQKAGINVNEKGTEAYAATVVEIENKFGGSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHS 442
            |.:..||.::::||||||.||:.:..:.....:.:....:.||||:..:.|.:|.::||.|||.:
Human   354 SKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVN 418

  Fly   443 P 443
            |
Human   419 P 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn27A	NP_652024.1	serpinK_insect_SRPN2-like	64..443	CDD:381044	91/389 (23%)
SERPINA11	NP_001073920.1	serpinA11	50..422	CDD:381025	92/391 (24%)