Protein Alignment eIF3h and EIF3H

DIOPT Version :10

• Sequence 1: NP_524834.2
• Gene: eIF3h / 45682
• FlyBaseID: FBgn0022023
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: XP_047278336.1
• Gene: EIF3H / 8667
• HGNCID: 3273
• Length: 365
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 114/250 - (45%)
• Similarity: 173/250 - (69%)
• Gaps: 0/250 - (0%)

  Fly    80 YQLTVMRRLRRVNVDHLHVGWYQSSDVGNSLSMALLESQYHYQTSIEESVVVVYDTQKSSRGFLC 144
            ||:.:||.||.||:||||||||||:..|:.::.|||:||:.||.:||||||::||..|:::|.|.
Human   112 YQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLS 176

  Fly   145 LKAYRLTPQAIQMYKDGDFTPEAFRTLKVGYENLFAEIPIVIKNSPLTNIMMSELNELLPEDKGH 209
            ||||||||:.:::.|:.||:|||.:...:.:|.:|.|:|||||||.|.|::|.||.:.......|
Human   177 LKAYRLTPKLMEVCKEKDFSPEALKKANITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKH 241

  Fly   210 NFLDLGTATVLENQMRSLIERVDELYQEAVRYNKYQQVVFKQDTEKHRALAKLAAENAVRTSKGE 274
            ..|.|.::..|...::.|::||||:.|:.|:||.|.:...||..:||:...:...||..|.|:||
Human   242 ELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGE 306

  Fly   275 PTVPEEEVIKQFRPMTAPNRLTATITSGQINTHAQHIAQFCSQSLAKLFITESLQ 329
            |.:|||::.|.|:|...|.|:.:.:.:|||||:.|:|.:|.:|:|.|||:.::||
Human   307 PPLPEEDLSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQ 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3h	NP_524834.2	MPN_eIF3h	20..281	CDD:163696	93/200 (47%)
EIF3H	XP_047278336.1	MPN	<100..185	CDD:472685	44/72 (61%)
		eIF3h_C	170..365	CDD:466087	78/191 (41%)