Protein Alignment Pdp1 and HLF

DIOPT Version :10

• Sequence 1: NP_729301.1
• Gene: Pdp1 / 45588
• FlyBaseID: FBgn0016694
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: XP_005257326.1
• Gene: HLF / 3131
• HGNCID: 4977
• Length: 296
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 120/250 - (48%)
• Similarity: 144/250 - (57%)
• Gaps: 34/250 - (13%)

  Fly   426 DKYKEEGDIWN--VEAQTAFLGPNLWDKTLPYDADLKVTQYADLDEFLSENNIPDGLPG--THLG 486
            ||.|:..|..|  ...|:|||||.|||||||||.|....:|.||:||||||.||.. |.  .|..
Human    45 DKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPS-PSQHDHSP 108

  Fly   487 HSSGLGHRSDSLGHAAGLS--------------------LGLGHITTKRERSPSPSDCISPDTLN 531
            |..||...|.:......||                    :..|.:......:|||   |.|||:.
Human   109 HPPGLQPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSP---IDPDTIQ 170

  Fly   532 -----PPSPAESTFSFASSGRDFDPRTRAFSDEELKPQPMIKKSRKQFVPDELK-DDKYWARRRK 590
                 .|.||:...|.......||||.|.||:|||||||||||:||.|:||:|| ||||||||||
Human   171 VPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKQDDKYWARRRK 235

  Fly   591 NNIAAKRSRDARRQKENQIAMRARYLEKENATLHQEVEQLKQENMDLRARLSKFQ 645
            ||:||||||||||.||||||:||.:|||||:.|.|||..|::|....:..|:|::
Human   236 NNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYE 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdp1	NP_729301.1	NAM-associated	514..609	CDD:464129	61/100 (61%)
		bZIP_HLF	580..639	CDD:269843	42/59 (71%)
		coiled coil	581..639	CDD:269843	41/57 (72%)
HLF	XP_005257326.1	bZIP_HLF	226..284	CDD:269843	41/57 (72%)
		coiled coil	226..284	CDD:269843	41/57 (72%)