Protein Alignment fwd and PI-4KBETA1

DIOPT Version :10

• Sequence 1: NP_001356971.1
• Gene: fwd / 45374
• FlyBaseID: FBgn0004373
• Length: 1682
• Species: Drosophila melanogaster
• Sequence 2: NP_201212.1
• Gene: PI-4KBETA1 / 836528
• AraportID: AT5G64070
• Length: 1121
• Species: Arabidopsis thaliana
• Alignment Length: 1152
• Identity: 291/1152 - (25%)
• Similarity: 425/1152 - (36%)
• Gaps: 372/1152 - (32%)

  Fly   680 LSTPSVASTA-SATPSVTPTPIATPTPTESTKNDQVLFKNFFGATKNAIFRTAQSIIENHEKKNA 743
            ||.|:..|.: |.:|........:..|.|..|    :||....:.|   .|.|...     :|:|
plant   185 LSPPTQKSLSFSPSPGTNVQDDGSQLPAEDNK----IFKKLIPSPK---VRDALMF-----RKSA 237

  Fly   744 AKQKEQPDHSGTVSLV---GSPNGGSSVP----------QDLVKSPTDISKKKE-FFSLLTSSSS 794
            .|..|:.:..|....:   ....|...:|          :|......||:...| ||..|.||..
plant   238 DKDDEESEKEGFFKRLLRDSKGEGDEPIPNSEGFFKRLLKDNKSEDEDITNSSEGFFKRLLSSKG 302

  Fly   795 IKAAAAAAANSAAS---TPPATPTEALAANSNSKLQPL----------SDPSA------------ 834
            ......::::....   .......|.|.|||:|..:.|          |:|::
plant   303 ESEELTSSSDGLFKRLLRDNKGDEEELGANSDSFFKRLLRESKNEDEESNPNSEGFFKKLFRDSK 367

  Fly   835 --DLKVKERTLNLRLPGDSEGSEGALTKCSSINSIHKL----KLPVPGVV--------------- 878
              |.||.:..       |.|..:|.|.|.....:..|.    |....|.|
plant   368 PEDDKVPKEV-------DDEDKDGFLKKLFREKNDDKRHGSEKNEANGTVYADKKSGEEDEREGF 425

  Fly   879 -KYFISEKAPVSDVLQKPEKGQSGLLRFFESPVFNIH---FAVH--------------YLFYSKE 925
             |.|..||:.....:.|.:.|...  ...|||.|::.   |.:|              .......
plant   426 FKKFFKEKSDDKKDIVKVDDGNES--EGDESPEFSLFKRLFRIHPEDAKPTSENENSSNGLVESS 488

  Fly   926 PGVLSFIGNKIFSFPDQEVDLYIPQLVVMYIQMDELAEVLDPYLTIRCRKSVDFSLKCLWLLEAY 990
            ||..:|. .|:|...||.|:
plant   489 PGTENFF-RKLFRDRDQSVE--------------------------------------------- 507

  Fly   991 NYQVDSLGNSHNSSRKSKLALMKEIFSKREHKQTQNDLKSAGTGGLHVGEPRSVVALAKKTHHRS 1055
                ||                 |:|..::||:.:            .|.|:
plant   508 ----DS-----------------ELFGSKKHKEKR------------PGSPK------------- 526

  Fly  1056 QSDATVLLADFRSPHTLSISHRMYQQPPYTTQTLPTTPAKLCLGDLTSGHAFDNGCTCFETVRGQ 1120
            |.|.|                      |.....||..                   |..:..:|.
plant   527 QRDDT----------------------PSGKPPLPNN-------------------TASQFRKGA 550

  Fly  1121 VNGLLGQRTLCSCGAPKTSPQKEFMKALMNVGKNLTSWPSKAEKTSALRMSLNLINKNL-----P 1180
            .:..|                 ||::||......|.......::...||.||..||.:|     .
plant   551 YHESL-----------------EFVQALCETSYGLVDIFPIEDRKIGLRESLAEINFHLSEAEIT 598

  Fly  1181 ARVWLPLYSDIPHHVVRITEEKTAVLNSKDKTPYIIYVEVVEIPDIYTSPLIPKMMPSLRHTKSE 1245
            ..:..|:...: ..||.|.|::..:|||::|.||:|.|||::..           .||.:.:.:.
plant   599 GGICFPMGRGV-FRVVHIPEDECILLNSREKAPYMISVEVLKAE-----------TPSAKESSNS 651

  Fly  1246 EHL--------DGSCL-------------------NSHQHLSCSRTSSCS--------------- 1268
            :.|        :|...                   ||...:|.|...:..
plant   652 QKLSKGGIPLANGDAFLQKPPPWAYPLWTTQEVYRNSADRMSLSTAQAIDQAMTPKSEVKVKLVN 716

  Fly  1269 ---SSQQGTSCRRKKGADVDGGCGDAGPHNSCSN--------VHSLGGLQFQEDDVWSQEEDEIT 1322
               |.:..||.....|..:|...|:| |....:|        |.:..||:.:     |..:..:.
plant   717 VSLSVEDRTSALESFGDPIDDVLGEA-PRTGLNNDLEWVRVVVTADPGLRME-----SIPDPSVP 775

  Fly  1323 AQYLNMRKVSERDTISQISLD---SCDSRDQGPPVVFNIGDVRLRHCSNLSCENTKSFSNDPEDP 1384
                  ||...|...|.::::   :..::.:.||              .|..:.....|:|.: |
plant   776 ------RKKEHRRVPSTVAMEEVRAAAAKGEAPP--------------GLPLKGAGQDSSDAQ-P 819

  Fly  1385 SA--AALKEP-------WHEKEKLIRESSPYGHLSNWRLLSAIVKCGDDLRQELMATQLLQMFKI 1440
            .|  ..|||.       |..|...||::|.||.|..|.|.|.|||.|||.|||.:|.||:..|..
plant   820 RANGGMLKEGDALSGELWEGKRDRIRKASIYGKLPGWDLRSIIVKSGDDCRQEHLAVQLISHFYD 884

  Fly  1441 IWQEEQVDLWVRPYKIVCLSNDSGLIEPILNTVSLHQIKKN--SNKSLKEYFIDEY--GSPSGES 1501
            |:||..:.||:|||:::..|:.:.|||.|.:|.|:|.||..  :..||:::|:.:|  .||   |
plant   885 IFQEAGLPLWLRPYEVLVTSSYTALIETIPDTASIHSIKSRYPNITSLRDFFVAKYKENSP---S 946

  Fly  1502 FRRAQKNFVQSCAAYCLISYLLQVKDRHNGNILFHSDGHIIHIDFGFILSISPKNLGFEQSPFKL 1566
            |:.||:|||:|.|.|.|:.||||||||||||:|...:||||||||||:||.||..:.||.:||||
plant   947 FKLAQRNFVESMAGYSLVCYLLQVKDRHNGNLLLDEEGHIIHIDFGFMLSNSPGGVNFESAPFKL 1011

  Fly  1567 TPEFVEVM----GGTSSEHWREFNKLLLVGMMSARKHMDRIINFVEIMRSNAHLPCFKNGCSGTV 1627
            |.|.:|||    .|..||.:..|..|.:.|.::.|||.:|||..||:::.:. .||||.| ..|:
plant  1012 TRELLEVMDSDADGVPSEFFDYFKVLCIQGFLTCRKHAERIILLVEMLQDSG-FPCFKGG-PRTI 1074

  Fly  1628 QNLRKRFHMNLTEQEMERKVEQLVQDSLKSLSTKLYDGYQYYTNGIL 1674
            ||||||||::|||::....|..|:..||.:..|:.||.||...||||
plant  1075 QNLRKRFHLSLTEEQCVSLVLSLISSSLDAWRTRQYDYYQRVLNGIL 1121

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fwd	NP_001356971.1	PI4Kc_III_beta	1385..1674	CDD:270712	143/305 (47%)
PI-4KBETA1	NP_201212.1	TFIIF_alpha	<300..>554	CDD:310411	58/395 (15%)
		PI4Kc_III_beta	831..1121	CDD:270712	139/294 (47%)