Protein Alignment shu and Fkbp8

DIOPT Version :10

• Sequence 1: NP_611837.1
• Gene: shu / 45360
• FlyBaseID: FBgn0003401
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001104536.1
• Gene: Fkbp8 / 14232
• MGIID: 1341070
• Length: 403
• Species: Mus musculus
• Alignment Length: 384
• Identity: 88/384 - (22%)
• Similarity: 143/384 - (37%)
• Gaps: 86/384 - (22%)

  Fly     6 EPYTPQLLKNPLSYSDLVKKGVEFEVDNSQQNHARDLGLDSDSDSDYEDALDVDG----EELRSP 66
            ||..|..|:.|  .:.|::   .|||            ||...|::.||  |:.|    |::..|
Mouse     6 EPSEPAALRLP--GAPLLE---GFEV------------LDGVDDAEEED--DLSGLPPLEDMGQP 51

  Fly    67 WTYSFDELRALMSEIDENIYKRITRTGHVDREAVPNKA-------------RVSVRYSGYWEGET 118
            .....::..||..|.          ....:.|..|..|             |:.....|. :|.:
Mouse    52 TVEEAEQPGALAREF----------LAATEPEPAPAPAPEEWLDILGNGLLRMKTLVPGP-KGSS 105

  Fly   119 AP---------FDSSLLRGSK------FVFETGQGTVVEGLEVAVRSMRPYEQAEFIISYKLLFG 168
            .|         ...||..|::      ..|..|...|::.|:::|..|...|.|......|..:|
Mouse   106 RPLKGQVVTVHLQMSLENGTRVQEEPELAFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG 170

  Fly   169 ELGC-PPRIKPKADALFKVEVIDYSLIGDAKGIDAIPQEDRDKFCVVYPKAVDLHLHGKDSVKLG 232
            ..|. .|.|.|.|....:|.:   ....|...::.:..::|........:..:.|....|.|
Mouse   171 PQGSRSPYIPPHAALCLEVTL---KTAEDGPDLEMLSGQERVALANRKRECGNAHYQRADFV--- 229

  Fly   233 RYQSAATAFE---RAVSSLNYCRMANDEEERKQTELLTTLNQNLMIVYNKMNKPK---RACIMMK 291
               .||.:::   :|::|.....|..:|||......:..|| ||.....|::..:   |:|  .:
Mouse   230 ---LAANSYDLAIKAITSNTKVDMTCEEEEELLQLKVKCLN-NLAASQLKLDHYRAALRSC--SQ 288

  Fly   292 ALRHLTMGNP-SCKALFQEGRALAALGEYNLARNAYLQAQAKQPANKEISDEIISMNKR 349
            .|.|    .| :.||||::|:.||..|||:.|......|...:|:||.|..|:..:.|:
Mouse   289 VLEH----QPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKK 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:459735	26/121 (21%)
		TPR repeat	218..257	CDD:276809	8/41 (20%)
		TPR	230..>389	CDD:440225	36/127 (28%)
		TPR repeat	262..295	CDD:276809	8/35 (23%)
		TPR repeat	304..329	CDD:276809	11/24 (46%)
Fkbp8	NP_001104536.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..54		8/27 (30%)
		FKBP_C	103..192	CDD:459735	21/91 (23%)
		TPR	210..>337	CDD:440225	37/139 (27%)
		TPR 1	212..245		6/38 (16%)
		TPR repeat	245..292	CDD:276809	12/49 (24%)
		TPR 2	263..296		10/39 (26%)
		TPR 3	297..330		13/32 (41%)
		TPR repeat	297..325	CDD:276809	12/27 (44%)