Protein Alignment shu and Fkbp10

DIOPT Version :10

• Sequence 1: NP_611837.1
• Gene: shu / 45360
• FlyBaseID: FBgn0003401
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_034351.2
• Gene: Fkbp10 / 14230
• MGIID: 104769
• Length: 581
• Species: Mus musculus
• Alignment Length: 150
• Identity: 43/150 - (28%)
• Similarity: 66/150 - (44%)
• Gaps: 15/150 - (10%)

  Fly   100 VPNKARVSVRYSGYWEGETAPFDSSLLRGSKFVFETGQGTVVEGLEVAVRSMRPYEQAEFIISYK 164
            |.|...|...|:|.....|| ||:|..||..:....|.|.:::|::..:..|.|.|:.:.||...
Mouse   170 VQNSDFVRYHYNGTLLDGTA-FDNSYSRGGTYDTYIGSGWLIKGMDQGLLGMCPGEKRKIIIPPF 233

  Fly   165 LLFGELGCPPRIKPKADALFKVEVIDYSLIGDAKGIDA--IPQEDRDKFCVVYPKAVD-LHLHGK 226
            |.:||.|....|.|:|..:|.|.::|.....|...::.  :||.     ||....|.| :..|..
Mouse   234 LAYGEKGYGTVIPPQASLVFYVLLLDVHNPKDTVQLETLELPQG-----CVRRAVAGDFMRYHYN 293

  Fly   227 DSVKLGRYQSAATAFERAVS 246
            .|:..|      |.|:.:.|
Mouse   294 GSLMDG------TLFDSSYS 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
shu	NP_611837.1	FKBP_C	96..189	CDD:459735	29/88 (33%)
		TPR repeat	218..257	CDD:276809	7/29 (24%)
		TPR	230..>389	CDD:440225	3/16 (19%)
		TPR repeat	262..295	CDD:276809
		TPR repeat	304..329	CDD:276809
Fkbp10	NP_034351.2	FKBP_C	54..146	CDD:459735
		FKBP_C	166..258	CDD:459735	29/88 (33%)
		FKBP_C	278..370	CDD:459735	9/35 (26%)
		FKBP_C	391..482	CDD:459735
		FRQ1	482..>567	CDD:444056
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	533..581
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	578..581