DRSC/TRiP Functional Genomics Resources

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Protein Alignment lin and LINS1

DIOPT Version :10

Sequence 1:NP_524815.1 Gene:lin / 45325 FlyBaseID:FBgn0002552 Length:858 Species:Drosophila melanogaster
Sequence 2:NP_001035706.2 Gene:LINS1 / 55180 HGNCID:30922 Length:757 Species:Homo sapiens


Alignment Length:424 Identity:103/424 - (24%)
Similarity:169/424 - (39%) Gaps:118/424 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   444 TLT--------DSESFDTTHLKCITIQKLEHKWPTLVKNMSELMAPTHQDAAEHC-----VLN-- 493
            |||        ||.|..|..||    |.|.| :.|:.:.....:...|   .|:|     ::|  
Human   193 TLTAIIKEIFKDSCSQKTEILK----QFLTH-FDTIFEVFYNSLFSQH---FENCRDTSKIVNIL 249

  Fly   494 --FLQLWENIISVKANLSIDET-------RPYYAQLD----KFELLLSHSLSCTVYKQMLCLFNE 545
              ||.|.|.:|:.:.:|.:..|       :| ...|:    ..:..:...:...:.|.:||...|
Human   250 MCFLDLLELLIASRIHLKLHFTCQRILFLKP-SCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGE 313

  Fly   546 ALCYGSTLALQ--------DMLPEETCKLAHQIVCHVRGFRILESLPRRQPDNMVSLIGYNGKPM 602
            .||.||..||.        |||     .||:.::..|.. .:|::|                  .
Human   314 DLCRGSVPALMPPDHHVAVDML-----ALANAVLQAVNS-GLLKTL------------------S 354

  Fly   603 VYANGTITLAHAAQSGDSEEDGAPLDLIEMDKTLLQKMVLLVLKSIAVTVKEIRSDSSDSSIDST 667
            ||..      |:...||..:....| :...|..:|:...|:::||:.:..:.. |.:|:..:|  
Human   355 VYEK------HSFFGGDEVQPECEL-ITSPDHVILRAASLVIMKSLEIKFQNY-SSASEVKVD-- 409

  Fly   668 DYDAFQDMMLIERSIRDVLSKLETFIKQTLEFHPECHFSKILIHLFDDQDDHLIEAMVCTLDV-- 730
                      ::|.:.::|:.|:..::.:|:.|..|   |.|..:|.:|||.::||...:|.:  
Human   410 ----------LQRFMSELLTFLKPHLQPSLQLHNPC---KWLSRVFIEQDDDMLEAAKASLGIYL 461

  Fly   731 ------------TSGISF-----RNNAFPELVAMLNPVYTFLEFLKMTSNSSDLLLDLLVSNETC 778
                        |.|...     ..|.:       ||...||.|||.....|.:|||.|:|:|||
Human   462 TLTRGCEATESLTQGKEMWDHHTHENGY-------NPHCIFLFFLKNIGFDSTVLLDFLISSETC 519

  Fly   779 FLLYLLRLLKYIRMNWTMFVHSCHTFGMGSAMLD 812
            ||.|.:|.||.::.:|..|...|:.|....:..|
Human   520 FLEYFVRYLKLLQKDWDNFFTICNNFDATESKYD 553

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
linNP_524815.1 LINES_N 441..801 CDD:464266 100/411 (24%)
LINES_C 814..850 CDD:464267
LINS1NP_001035706.2 LINES_N 193..542 CDD:464266 100/411 (24%)
LINES_C 712..747 CDD:464267
Blue background indicates that the domain is not in the aligned region.

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