DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tom40 and TOM40

DIOPT Version :9

Sequence 1:	NP_001259313.1	Gene:	Tom40 / 44978	FlyBaseID:	FBgn0016041	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_188634.1	Gene:	TOM40 / 821538	AraportID:	AT3G20000	Length:	309	Species:	Arabidopsis thaliana

Alignment Length:	330	Identity:	91/330 - (27%)
Similarity:	147/330 - (44%)	Gaps:	50/330 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 AEGLDSLAAAK-DAA-----------LENPGTVEELHKKC-KDIQAITFEGAKIMLNKGLSNHFQ 94
            |:.|..|.||: ||.           |.:|...||||::. ..:::..|||.:....:.|:..|.
plant     2 ADLLPPLTAAQVDAKTKVDEKVDYSNLPSPVPYEELHREALMSLKSDNFEGLRFDFTRALNQKFS 66

  Fly    95 VSHTINMSNV------------VPSG-YRFGATYVGTKEFSPTEAFPVLLGDIDPAGNLNANVIH 146
            :||::.|...            :|:. |.|||.|...|        .:|:|.:...|.|||.:..
plant    67 LSHSVMMGPTEVPAQSPETTIKIPTAHYEFGANYYDPK--------LLLIGRVMTDGRLNARLKA 123

  Fly   147 QFSARLRCKFASQI-QESKVVASQLTTDYRGSDYTLSLTVANPSIFTNSGVVVGQYLQSVTPALA 210
            ..:.:|..|..:.| .|..:..:....||.||||...|.:.      .|.::...|:||||..|:
plant   124 DLTDKLVVKANALITNEEHMSQAMFNFDYMGSDYRAQLQLG------QSALIGATYIQSVTNHLS 182

  Fly   211 LGSELAYQFGPNVPGRQIAIMSVVGRYTAGSSVWSGTLGQSGLHVC-YYQKASDQLQIGAEVETS 274
            ||.|:.:...|...|     :....||.....|.||.:..:|..|. |.||.||::.:..:...:
plant   183 LGGEIFWAGVPRKSG-----IGYAARYETDKMVASGQVASTGAVVMNYVQKISDKVSLATDFMYN 242

  Fly   275 LRMQESVATLAYQIDLPKANLVFRGGIDSNWQIFGVLEKRLAPLPFTLALSGRMNHVKNNFRLGC 339
            ...::..|::.|...|.:|.:  ||.||||.....:||:||: :.....||..::|.|.:::.|.
plant   243 YFSRDVTASVGYDYMLRQARV--RGKIDSNGVASALLEERLS-MGLNFLLSAELDHKKKDYKFGF 304

  Fly   340 GLMIG 344
            ||.:|
plant   305 GLTVG 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tom40	NP_001259313.1	Porin3_Tom40	57..344	CDD:132766	83/302 (27%)
TOM40	NP_188634.1	Porin3_Tom40	28..309	CDD:132766	83/302 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I2428
eggNOG	1	0.900	-	-		E1_KOG3296
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I2156
OMA	1	1.010	-	-		QHG55758
OrthoDB	1	1.010	-	-		D1346842at2759
OrthoFinder	1	1.000	-	-		FOG0001620
OrthoInspector	1	1.000	-	-		mtm1190
orthoMCL	1	0.900	-	-		OOG6_101593
Panther	1	1.100	-	-	LDO	PTHR10802
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840