Protein Alignment Tom40 and Tomm40l

DIOPT Version :10

• Sequence 1: NP_652003.2
• Gene: Tom40 / 44978
• FlyBaseID: FBgn0016041
• Length: 344
• Species: Drosophila melanogaster
• Sequence 2: NP_001032247.1
• Gene: Tomm40l / 641376
• MGIID: 3589112
• Length: 308
• Species: Mus musculus
• Alignment Length: 326
• Identity: 132/326 - (40%)
• Similarity: 192/326 - (58%)
• Gaps: 24/326 - (7%)

  Fly    21 LGLQEPAPLPSNSGSLTESSSSAEGLDSLAAAKDAALENPGTVEELHKKCKDIQAITFEGAKIML 85
            |||.....||..|                 ..::..|.|||:.:|||:.|||:.....||.|:::
Mouse     5 LGLAPMGTLPRRS-----------------HRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVV 52

  Fly    86 NKGLSNHFQVSHTINMSNVVPSGYRFGATYVGTKEFSPTEAFPVLLGDIDPAGNLNANVIHQFSA 150
            ||.||:||||:||::||.:...||.....|.|..:.||||.||.::||:|.:|:|||.|:...:.
Mouse    53 NKVLSSHFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAE 117

  Fly   151 RLRCKFASQIQESKVVASQLTTDYRGSDYTLSLTVANPSIFTNSGVVVGQYLQSVTPALALGSEL 215
            |||.|...|.|::|.:..|...:|||.|||.:||:.||.:...|.::|..:|||:|..|.||.||
Mouse   118 RLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSITHRLVLGGEL 182

  Fly   216 AYQFGPNVPGRQIAIMSVVGRYTAGSSVWSGTL--GQSGLHVCYYQKASDQLQIGAEVETSLRMQ 278
            .|.   ..||.:.||:::.|:|:|..  |..||  |..|.|..||.||::|:|:|.|.|.:.|:|
Mouse   183 VYH---RRPGEEGAILTLAGKYSAVH--WVATLNVGSGGAHASYYHKANEQVQVGVEFEANTRLQ 242

  Fly   279 ESVATLAYQIDLPKANLVFRGGIDSNWQIFGVLEKRLAPLPFTLALSGRMNHVKNNFRLGCGLMI 343
            ::..:..|.:.||:|::||||.:||||.:..||||::.|||.||||...:||.:|.|..|..:.:
Mouse   243 DTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITV 307

  Fly   344 G 344
            |
Mouse   308 G 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tom40	NP_652003.2	Porin3_Tom40	57..344	CDD:132766	125/288 (43%)
Tomm40l	NP_001032247.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		9/40 (23%)
		Porin3_Tom40	24..308	CDD:132766	125/288 (43%)
		Required for mitochondrial targeting. /evidence=ECO:0000250	281..308		12/26 (46%)