DRSC/TRiP Functional Genomics Resources

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Protein Alignment mys and ITGBL1

DIOPT Version :10

Sequence 1:NP_524793.2 Gene:mys / 44885 FlyBaseID:FBgn0004657 Length:846 Species:Drosophila melanogaster
Sequence 2:NP_004782.1 Gene:ITGBL1 / 9358 HGNCID:6164 Length:494 Species:Homo sapiens


Alignment Length:394 Identity:108/394 - (27%)
Similarity:136/394 - (34%) Gaps:153/394 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   439 SSCLSNGP-EVQTSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTML 502
            |:|..:|. :....|||....|....:.....|.|...                |::.:....::
Human   102 STCAGHGKCDCGKCKCDQGWYGDACQYPTNCDLTKKKS----------------NQMCKNSQDII 150

  Fly   503 CS---------CPCENPGSIGY---------------QVQANSCSGHGTSMCGICNCDDSYFGNK 543
            ||         |.|:|....|.               ......|.|||...||.|.|...:.|:|
Human   151 CSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCKAGWHGDK 215

  Fly   544 CE--CSATDLTSKFANDTSCRADSTSTTDCSGRGHCVCGACECHKRPNPIEI--------ISGKH 598
            ||  |..|...||      .|..|.....||.||.||||.|.||      ::        |.|..
Human   216 CEFQCDITPWESK------RRCTSPDGKICSNRGTCVCGECTCH------DVDPTGDWGDIHGDT 268

  Fly   599 CECDNFSC----ERNRNQLCSGPDHGTCECGRCKCKPGWTGSNC---------------GCQESN 644
            ||||...|    :|..:..|||  ||.|.||||.||.||.|..|               .||.|:
Human   269 CECDERDCRAVYDRYSDDFCSG--HGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSS 331

  Fly   645 D--------------TCMPPG-------------------GGEICSGHGTCECGVCKCTVNDQGR 676
            |              ||.|||                   .|.:|.|||||.||.|.|   ::|.
Human   332 DLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVC---ERGW 393

  Fly   677 FSGRHCE---KCP----------------TCSGR--CQELKDCVQC-----QMYKTGELKNGDDC 715
            | |:.|:   ||.                .|||:  |.    |.:|     :.|.:||..:.|| 
Human   394 F-GKLCQHPRKCNMTEEQSKNLCESADGILCSGKGSCH----CGKCICSAEEWYISGEFCDCDD- 452

  Fly   716 ARNC 719
             |:|
Human   453 -RDC 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mysNP_524793.2 INB 45..505 CDD:197563 12/75 (16%)
Integrin_B_tail 692..775 CDD:462325 10/33 (30%)
Integrin_b_cyt 803..843 CDD:462580
ITGBL1NP_004782.1 Cysteine-rich tandem repeats 51..494 108/394 (27%)
Blue background indicates that the domain is not in the aligned region.

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