Protein Alignment mys and itgb1

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_012819879.1
• Gene: itgb1 / 394767
• XenbaseID: XB-GENE-946725
• Length: 801
• Species: Xenopus tropicalis
• Alignment Length: 868
• Identity: 348/868 - (40%)
• Similarity: 491/868 - (56%)
• Gaps: 107/868 - (12%)

  Fly    12 ALLMIAILAAIAGQTDAQKAAKLTAVSTC--ASKEKCHTCIQT-EGCAWCMQPDF--KGQ---SR 68
            ::|...:|..:|...:||:..     :.|  |:.:.|..|||. ..|.||.:.:|  :|:   :|
 Frog     5 SVLTFGLLTCLALCINAQQGG-----TECLKANAKSCGECIQAGPNCGWCTKVNFLQEGEPTSAR 64

  Fly    69 CYQNTSSL----CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSS 129
            | .:.::|    ||||...:|...:|.|.:..:||:.|.
 Frog    65 C-DDLAALKNKGCPEEDIQNPRGRKQKLKDIPITNKGKG-------------------------- 102

  Fly   130 SFYSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLS 194
                            |......|.||:||.:...||..|.....:::.:||.||:|||||||||
 Frog   103 ----------------ERMDPANITQIRPQQLVFELRSGEPQTFNLTFRRAEDYPIDLYYLMDLS 151

  Fly   195 KSMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPC---ENCKAPY 256
            .||:||...:.:||..|...|::||::|.:||||||:|.:|||:||.|.||.:||   :||.:|:
 Frog   152 FSMKDDLENVKSLGTALMTEMEKITSDFRIGFGSFVEKTVMPYISTTPAKLINPCTSDQNCTSPF 216

  Fly   257 GYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAG 321
            .|:|.:.|.::.:.|::.|....:|||||:||||||||||...|..||||| ...||||||||||
 Frog   217 SYKNVLNLTSDGKLFNDLVGKQQISGNLDSPEGGFDAIMQVAVCGEQIGWR-NVTRLLVFSTDAG 280

  Fly   322 FHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVY 386
            ||:||||||||::.||||:|||. ...||.|...|||||:.:.||:.:|.|..|||||.....||
 Frog   281 FHFAGDGKLGGIVLPNDGKCHLH-GNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEDFQPVY 344

  Fly   387 EKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDNATGD-VKITYFSSCLS--NGPEV 448
            ::|...|..|:...|.::||||::|:.:.|..:||.:.::::...: |.|:|.|.|.:  .|...
 Frog   345 QELKNLIPKSAVGTLSSNSSNVIQLIIDSYNSLSSELILENSKLPEGVTISYKSFCKNGVKGTGE 409

  Fly   449 QTSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSI 513
            ...||.|:..|.||.|...:...|||:  :...::|.|.|:|..|.::|.|..:|.|.|:..|:
 Frog   410 DGRKCSNISIGDQVEFEISVTAHKCPK--KGQAESIKIKPLGFTEEVEIVLQFICECDCQEKGT- 471

  Fly   514 GYQVQANS--C-SGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRG 575
                 .||  | .|:||..||.|.|::...|.:||||..::.|: ..|..||.:::|.. ||..|
 Frog   472 -----PNSPECHHGNGTFECGACRCNEGRIGKECECSTDEVNSE-DMDAYCRRENSSEI-CSNNG 529

  Fly   576 HCVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGC 640
            .|:||.|.|.||.||.|:.|||:||||||:|:|:...:|.|  .|.|:|..|:|.|.::||.|.|
 Frog   530 DCICGQCVCKKRDNPNEVYSGKYCECDNFNCDRSNGLICGG--KGVCKCRVCECFPNYSGSACDC 592

  Fly   641 QESNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYK 705
            .|...|||.. .|:||:|.|.|:||.||||   ..:|.|..||.|.||.|.|.|.|:||||:.::
 Frog   593 SEDTSTCMAK-NGQICNGRGICDCGRCKCT---DPKFQGPTCELCQTCVGVCTEHKECVQCRAFQ 653

  Fly   706 TGELKNGDDCARNCTQFVPVGVEKVEIDETKDE----------QMCKFFDEDDCKFMFKYS--EQ 758
            .||.:  :.|...|..|      .:.:.|::::          ..||..|.:||.|.|.||  .:
 Frog   654 KGEKQ--EVCLEQCMHF------NISLVESREDLPQPGQAEALTHCKEKDAEDCWFYFTYSVDSK 710

  Fly   759 GELHVYAQENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKW 823
            .|:.|:..:..|||:...::.||.||:|.|||:|||:||:||||..||||||||:||||:|||||
 Frog   711 NEVLVHVVKEPECPSGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKW 775

  Fly   824 DTGENPIYKQATSTFKNPMYAGK 846
            ||.||||||...:.||||.|..|
 Frog   776 DTQENPIYKSPINNFKNPNYGRK 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	183/475 (39%)
		Integrin_B_tail	692..775	CDD:462325	27/94 (29%)
		Integrin_b_cyt	803..843	CDD:462580	29/39 (74%)
itgb1	XP_012819879.1	INB	35..464	CDD:197563	183/475 (39%)
		I-EGF_1	466..495	CDD:465729	12/34 (35%)
		Integrin_B_tail	640..727	CDD:462325	27/94 (29%)
		Integrin_b_cyt	755..795	CDD:462580	29/39 (74%)