Protein Alignment mys and Itgb8

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_796264.2
• Gene: Itgb8 / 320910
• MGIID: 1338035
• Length: 767
• Species: Mus musculus
• Alignment Length: 795
• Identity: 247/795 - (31%)
• Similarity: 367/795 - (46%)
• Gaps: 144/795 - (18%)

  Fly    24 GQTDAQKAAKLTAVSTCASKEKCHTCIQT-EGCAWCMQPDF----KGQSRCYQNTSSL----CPE 79
            ||::..:......||       |..|:|. ..|.||:|.||    .|..|| ...|||    ||.
Mouse    40 GQSEHNRCGSANVVS-------CARCLQLGPECGWCVQEDFVSGGSGSERC-DTVSSLISKGCPV 96

  Fly    80 EFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFYSQSSSGSSSASG 144
            :      ::|.:                            |.:..:||.:...:|.:.|..|
Mouse    97 D------SIEYL----------------------------SVHVVTSSENEINTQVTPGEVS--- 124

  Fly   145 YEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSMEDDKAKLSTLGD 209
                     ||:.|         ..:.|..:.....:.||||||||:|:|.||.::..||:::|:
Mouse   125 ---------VQLHP---------GAEANFMLKVRPLKKYPVDLYYLVDVSASMHNNIEKLNSVGN 171

  Fly   210 KLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCE----NCKAPYGYQNHMPLNNNTES 270
            .||:.|...:.:|.|||||:|||.:.||:|..|:::.:.|.    :|..|:||.:.:.|..|...
Mouse   172 DLSKKMALYSRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITE 236

  Fly   271 FSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGFHYAGDGKLGGVIA 335
            |...|....:|||:|.|||||||::||..|.|.||||::|:|||:..||...|.|.|.||.|::.
Mouse   237 FEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIVV 301

  Fly   336 PNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYEKLVEHIQGSSAAK 400
            ||||.|||. ...|..||..::||:.|:::|:.||.||:||||...|...|:.|:..:.|:.|.:
Mouse   302 PNDGNCHLK-NNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGAIAGE 365

  Fly   401 LDNDSSNVVELVKEEYRKISSSVEMK-DNATGDVKITYFSSCLSNGPEVQTSKCDNLKEGQQVSF 464
            :::.::|:..||.|.|:||.|.|::: :|....|.....:.|.....:...|.|.|:....:|.|
Mouse   366 IESKAANLNNLVVEAYKKIISEVKVQLENQVHGVHFNITAICPDGARKPGISGCGNVTSNDEVLF 430

  Fly   465 TAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCEN----PGSIGYQVQANSCSGH 525
            ...:.:..|  |.........|.|:|.||..::.:...|||.|||    .|..........|.
Mouse   431 NVTVVMKTC--DIMGGKNYAIIKPIGFNETTKVHIHRSCSCQCENHRGLKGQCAEAAPDPKCP-- 491

  Fly   526 GTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHCVCGACECHKRPNP 590
                    .||||    :|...    ..:|.::| |:....... |||||.|:||.|.|||  ..
Mouse   492 --------QCDDS----RCHFD----EDQFPSET-CKPQEDQPV-CSGRGVCICGKCLCHK--TK 536

  Fly   591 IEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQESNDTCMPPGGGEI 655
            :..:.|::||.|:|||......:|:|  ||.||.|||:|..||.|..|.|..::........|::
Mouse   537 LGRVYGQYCEKDDFSCPYLHGDVCAG--HGECEGGRCQCFSGWEGDRCQCPSASAQHCVNSKGQV 599

  Fly   656 CSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTGELKNGDDCARNCT 720
            |||.|||.||.|:||   ..|..||.||.||||...|.|..:|:||...........|.|..:|.
Mouse   600 CSGRGTCVCGRCECT---DPRSIGRLCEHCPTCHLSCSENWNCLQCLHPHNLSQAALDQCKSSCA 661

  Fly   721 QFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSEQGELHVYAQENKECPAKVFMLGIVMGVI 785
            .     :|:..:|:|           .:|     .|....|.::           |::.||..:|
Mouse   662 V-----MEQHRMDQT-----------SEC-----LSGPSYLRIF-----------FIIFIVTFLI 694

  Fly   786 AAI-VLVGLAILLLW 799
            ..: ||:...::|.|
Mouse   695 GLLKVLIIRQVILQW 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	151/473 (32%)
		Integrin_B_tail	692..775	CDD:462325	14/82 (17%)
		Integrin_b_cyt	803..843	CDD:462580
Itgb8	NP_796264.2	INB	54..469	CDD:197563	152/480 (32%)