Protein Alignment mys and pat-3

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_497787.1
• Gene: pat-3 / 175504
• WormBaseID: WBGene00003930
• Length: 809
• Species: Caenorhabditis elegans
• Alignment Length: 866
• Identity: 366/866 - (42%)
• Similarity: 499/866 - (57%)
• Gaps: 95/866 - (10%)

  Fly    12 ALLMIAILAAIAGQTDAQKAAKLT------AVSTCASKEK----CHTCIQ-TEGCAWCMQPDF-- 63
            :||::|.|...|......|..::|      :...|.|..:    |..||| .|.||||..|.|
 Worm     6 SLLLLAALLPFALPASDWKTGEVTGKVVEKSEFPCYSLSRDNYTCSACIQYHESCAWCGAPMFDE 70

  Fly    64 -KGQSRCYQNTSSL---CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSS 124
             |..:||......:   ||..:...|.|...|..::||::|.:.|
 Worm    71 KKPYARCDSRAKLMEHGCPNSYIEDPATKLDITEDSKLSDQGQVE-------------------- 115

  Fly   125 SSSSSSFYSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYY 189
                                    |..|.|||:||.|.:.:|...:....::|.||..|||||||
 Worm   116 ------------------------SEEEAVQIKPQEMYVEIRPKSRVRFNVTYRQAVDYPVDLYY 156

  Fly   190 LMDLSKSMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCEN-CK 253
            |||||.||:|||.|||.|||.|:|.|:.:|.||.||||||:||.|||::....:|...||.. |.
 Worm   157 LMDLSYSMKDDKQKLSELGDLLAERMRTVTKNFRLGFGSFIDKKLMPFIDPRIEKQLSPCPTPCA 221

  Fly   254 APYGYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFST 318
            .|||:::.|.|..||..|..||..|.:|||||||||||||::||:||...|||||:||:::||||
 Worm   222 EPYGFKHQMSLTTNTAKFKAEVDKAEISGNLDAPEGGFDAVVQALACNKTIGWRERARKMIVFST 286

  Fly   319 DAGFHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQL 383
            |||||:||||:|.||:.||||.|||..:|.||.:..||||||:.::|.:||...|:|||||.:..
 Worm   287 DAGFHFAGDGRLAGVVEPNDGTCHLDREGYYTETLNQDYPSIALLHQMIKDRKANVIFAVTKNNQ 351

  Fly   384 SVYEKLVEHIQ--GSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDNATGD--VKITYFSSCLSN 444
            .:|.:|...:.  .||...|.|||.|:|:|:::||.|||..:.|.|||...  :|:||.|.||..
 Worm   352 DLYTQLSNALPDVSSSVGVLANDSRNIVDLIEKEYLKISEKIIMVDNANASEGLKLTYRSMCLDG 416

  Fly   445 GPEVQTSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCEN 509
            .....|:.|:.::.|.:|.|...::...| .|.||:  .:.|.|.|::|.:.:.:.:||.|.||.
 Worm   417 TTLKDTNVCEGIRVGDEVQFEVTLENTHC-IDKRDF--VLRIGPSGLDETLIVNVKVLCDCDCER 478

  Fly   510 PGSIGYQVQANS--CSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCS 572
            ..    ::..||  |:| |..:||:|.|.....|..|||:...:::...|: .|:..:.|.. |.
 Worm   479 QD----RIVTNSADCNG-GDMVCGVCRCKGGNVGKYCECNRPGMSTAALNE-KCKRTNESAI-CE 536

  Fly   573 GRGHCVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSN 637
            |||.|.||.|||:.|.||.|.|||:.||||||:|.|:..::|:  :||.|.||:|.|.|||||..
 Worm   537 GRGVCNCGRCECNPRANPEEQISGEFCECDNFNCPRHDRKICA--EHGECNCGKCICAPGWTGRA 599

  Fly   638 CGCQESNDTCMPPGGGEICSGHGTCECGVCKCTVNDQG-RFSGRHCEKCPTCSGRCQELKDCVQC 701
            |.|..|.|:|: ...|:||:|.|.|.||.|:|..:..| |:||..||.||||..:|.|.|:||.|
 Worm   600 CECPISTDSCL-SANGKICNGKGECICGRCRCFDSPDGNRYSGAKCEICPTCPTKCVEYKNCVMC 663

  Fly   702 QMYKTGELKNG--DDCARNCTQFVPVGVEKVEIDETKDEQMCKFFD-EDDCKF--MFKYSEQGE- 760
            |.::||.|...  |.|     :|..:.||  |:....:...|:|.| .|||.|  ::.|.|..:
 Worm   664 QQWQTGPLNETACDQC-----EFKVIPVE--ELPNLNETTPCQFVDPADDCTFYYLYYYDEATDN 721

  Fly   761 LHVYAQENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDT 825
            ..|:.:::|:||..|.:|.||:||||.||::|:.:||||||||.:|||.|:|.|..||:.|||||
 Worm   722 ATVWVRKHKDCPPPVPVLAIVLGVIAGIVILGILLLLLWKLLTVLHDRSEYATFNNERLMAKWDT 786

  Fly   826 GENPIYKQATSTFKNPMYAGK 846
            .|||||||||:|||||:||||
 Worm   787 NENPIYKQATTTFKNPVYAGK 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	196/475 (41%)
		Integrin_B_tail	692..775	CDD:462325	29/88 (33%)
		Integrin_b_cyt	803..843	CDD:462580	28/39 (72%)
pat-3	NP_497787.1	INB	49..474	CDD:197563	196/471 (42%)
		Integrin_B_tail	654..736	CDD:462325	29/88 (33%)
		Integrin_b_cyt	767..804	CDD:462580	27/36 (75%)