Protein Alignment mys and Itgb2l

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_006522991.1
• Gene: Itgb2l / 16415
• MGIID: 1277979
• Length: 795
• Species: Mus musculus
• Alignment Length: 795
• Identity: 236/795 - (29%)
• Similarity: 360/795 - (45%)
• Gaps: 135/795 - (16%)

  Fly    18 ILAAIAGQTDAQKAAKLTAVSTCASKEKCHTCIQT-EGCAWCMQPDFKGQSRCYQNTSSLCPEEF 81
            :|..:||....:.|  |:.:.|..:...|..||:: ..||||.:.:|.|:.   :..|..|.
Mouse     7 LLPVLAGLLSLESA--LSQLCTKDNVSTCQDCIRSGPSCAWCQKLNFTGRG---EPDSVRCD--- 63

  Fly    82 AYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFYSQSSSGSSSASGYE 146
                 |.||:|:.. .|::|..:                                  ..|.:..:
Mouse    64 -----TPEQLLLKG-CTSEYLVD----------------------------------PKSLAESQ 88

  Fly   147 EYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSMEDDKAKLSTLGDKL 211
            |....:..|:.|:::.:.||..:....|:.:.:.:...||||:||.||.|.:...:.:.|||..|
Mouse    89 EDKERDQRQLSPRNVTVFLRPGQAATFKVDFQRTQDNSVDLYFLMGLSGSAQGHLSNVQTLGSDL 153

  Fly   212 SETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCENCKAPYGYQNHMPLNNNTESFSNEVK 276
            .:.:..|:.:..:||||.|:..                        :|:.:.|..::..|..|::
Mouse   154 LKALNEISRSGRIGFGSIVNMT------------------------FQHILKLTADSSQFQRELR 194

  Fly   277 NATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGFHYAGDGKLGGVIAPNDGEC 341
            ...|||.|..|:|..||::|...|..:|||| ...|.||..||..||.|.|..||.....:||.|
Mouse   195 KQLVSGKLATPKGQLDAVVQVAICLGEIGWR-NGTRFLVLVTDNDFHLAKDKTLGTRQNTSDGRC 258

  Fly   342 HLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYEKLVEHIQGSSAAKLDNDSS 406
            ||. .|.|......||.|:.|:..|:.:|.|..||.|.:..:..||||...|...:..:|.:|||
Mouse   259 HLD-DGMYRSRGEPDYQSVVQLASKLAENNIQPIFVVPSRMVKTYEKLTTFIPKLTIGELSDDSS 322

  Fly   407 NVVELVKEEYRKISSSVEMKDNATGDV-KITYFSSCLSNG---PEVQTSKCDNLKEGQQVSFTAQ 467
            ||.:|::..|.|:||.|.:..:....: |:||.|.| |||   |...:..|..::...||:|...
Mouse   323 NVAQLIRNAYSKLSSIVVLNHSTIPSILKVTYDSYC-SNGTSNPGKPSGDCSGVQINDQVTFQVN 386

  Fly   468 IQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGYQVQANS-CSGHGTSMCG 531
            |...:|..:     |...|..:|..:.:.:::..||.|.|:.      |.|.:| |.|.|...||
Mouse   387 ITASECFRE-----QFFFIQALGFMDSVTVRVLPLCECQCQE------QSQHHSLCGGKGAMECG 440

  Fly   532 ICNCDDSYFGNKCEC-----SATDLTSKFANDTSCRADSTSTTDCSGRGHCVCGACECHKRPNPI 591
            ||.|:..|.|..|||     |:.||      :.|||.|::|.. |||.|.|:||.||||....|.
Mouse   441 ICRCNSGYAGKNCECQTQGPSSQDL------EGSCRKDNSSIM-CSGLGDCICGQCECHTSDIPN 498

  Fly   592 EIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQESNDTCMPPGGGEIC 656
            :.|.|::|||:|.:|||...|:|.||:.|.|.||||.|:.|:.||.|.|:.|...|:.....| |
Mouse   499 KEIYGQYCECNNVNCERYDGQVCGGPERGHCSCGRCFCRYGFVGSACQCRMSTSGCLNNRMVE-C 562

  Fly   657 SGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTGELKNGDDCARNCTQ 721
            ||||.|.|..|.|   |.| :....|||.|....||.|...|.:|       ||  |:.|..|.:
Mouse   563 SGHGRCYCNRCLC---DPG-YQPPLCEKRPGYFHRCSEYYSCARC-------LK--DNSAIKCRE 614

  Fly   722 -----FVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSEQGELH-VYAQENKECPAKV----F 776
                 |.............:|.:.|.      ..:.....:|.::: :|.:|:..| |::    .
Mouse   615 CWNLLFSNTPFSNKTCMTERDSEGCW------TTYTLYQPDQSDINSIYIKESLVC-AEISNTTI 672

  Fly   777 MLGIVMGVIAAIVLV 791
            :||:::||:.|::.:
Mouse   673 LLGVIVGVLLAVIFL 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	126/464 (27%)
		Integrin_B_tail	692..775	CDD:462325	17/88 (19%)
		Integrin_b_cyt	803..843	CDD:462580
Itgb2l	XP_006522991.1	vWFA	32..419	CDD:469594	126/464 (27%)
		I-EGF_1	417..448	CDD:465729	14/36 (39%)