Protein Alignment mys and itgb6

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_003199474.1
• Gene: itgb6 / 100499533
• ZFINID: ZDB-GENE-100812-2
• Length: 782
• Species: Danio rerio
• Alignment Length: 854
• Identity: 290/854 - (33%)
• Similarity: 436/854 - (51%)
• Gaps: 112/854 - (13%)

  Fly    11 LALLMIAILAAIAGQTDAQKAAKLTAVSTCA--SKEKCHTCIQT-EGCAWCMQPDFKG----QSR 68
            |.|::...|.::.|              ||:  |...|..|:|. ..||||...:|..    ..|
Zfish     6 LCLVLYFWLDSVGG--------------TCSQISALSCDDCLQLGPQCAWCTLQNFTDFFPVDER 56

  Fly    69 CYQNTSSL---CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSS 130
            |....:.|   |..||...|:|..::|.:..|...              ||.::.||
Zfish    57 CDTPEALLQKGCSGEFVEFPVTNVKVLKDQGLGKN--------------SGHTNVSY-------- 99

  Fly   131 FYSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSK 195
                                     |.||.|||.||...:...:|...|.:.:|||:|||||||.
Zfish   100 -------------------------IAPQKMRLQLRPGSQLTFQIQVQQPKDHPVDIYYLMDLSA 139

  Fly   196 SMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCEN----CKAPY 256
            ||.||..|:..||..||:.|..:|:.|.|||||||:|.::|::....::|.:||.:    |...:
Zfish   140 SMFDDLKKIKDLGSTLSKEMANLTSKFRLGFGSFVEKPVLPFIKITREELANPCRSFDLECLPTF 204

  Fly   257 GYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAG 321
            ||::.:.|.::|:.|:..:....:|.|:|.|||||||||||..|..:||||..:.:||||.:||.
Zfish   205 GYRHLLSLTSSTDRFNEIISKQQISANIDIPEGGFDAIMQAAVCGDRIGWRNDSMKLLVFVSDAD 269

  Fly   322 FHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVY 386
            .|:..|.|:.|::.||||||||....||:.:...:||::.|:..|:.:|.|.:|||||..|...|
Zfish   270 SHFGMDSKMSGIVVPNDGECHLDGNNEYSMTAHLEYPTLGQLVDKLVENNILLIFAVTKDQKENY 334

  Fly   387 EKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMK--DNATGDVKITYFSSCLSNGPEVQ 449
            |.....|.|::...|.:||.|::||:...|:::.|.::::  .|..| :::::.:.|........
Zfish   335 ENYASLIPGATVGVLASDSRNILELIMTSYKELRSEIDLEVLGNTEG-LQMSFTALCQDGTITPG 398

  Fly   450 TSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPC-ENPGSI 513
            ...|.|:|.|..|||...:::..|...||.::    :.|||..:.::|:|...|.|.| :.|
Zfish   399 HKNCTNVKAGDVVSFNVTVEIKGCLGGPRRFS----LRPVGFQDALEIELESQCVCSCHQTP--- 456

  Fly   514 GYQVQANSCS-GHGTSMCGICNCDDSYFGNKCECS-ATDLTSKFANDTSCRADSTSTTDCSGRGH 576
              :..::.|| |.|...||.|.||..:.|.||||: :.|..|      .|||:..:.. |||:|.
Zfish   457 --ETNSSFCSRGRGALECGECVCDPGFVGPKCECTESQDQVS------DCRANEGAEV-CSGQGE 512

  Fly   577 CVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQ 641
            |.||.|.|  .|:....:.|.:||||||||.|.|.:||.|  ||.|:||.|.|..||.|..|.|.
Zfish   513 CFCGQCVC--LPSSFGRVYGPYCECDNFSCLRFRGELCGG--HGECDCGECVCDSGWMGEFCNCS 573

  Fly   642 ESNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKT 706
            .||.:|: ...|.:|||.|.|.||.|:|:|...   ||:|||:||||...|...:.|.:| ..|.
Zfish   574 TSNRSCV-SSDGSVCSGRGRCVCGKCECSVPGA---SGKHCERCPTCGDICSIHRSCAEC-FLKA 633

  Fly   707 GELKNGDDCARNCTQFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKY--SEQGELHVYAQENK 769
            .|  ..|:||..|:..........:.:|:: ...|....|:.|...|..  |:.|.: :|..:..
Zfish   634 KE--PSDECAVKCSSLHTAVSNSTDFEESR-AAPCTLQSEESCLLSFSLVASDHGSI-IYNPKLY 694

  Fly   770 ECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQA 834
            :|........|.:||..:::::|:|:|::||.|.::|||:|.|:||.|:..|||.:|.||:::.:
Zfish   695 DCSEPPNAPLIALGVCMSVLIIGIALLVIWKFLVSVHDRKEVAKFEAEKAKAKWQSGTNPLFRSS 759

  Fly   835 TSTFKNPMY 843
            ||||||..|
Zfish   760 TSTFKNVTY 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	154/473 (33%)
		Integrin_B_tail	692..775	CDD:462325	18/84 (21%)
		Integrin_b_cyt	803..843	CDD:462580	20/39 (51%)
itgb6	XP_003199474.1	INB	28..450	CDD:197563	154/473 (33%)
		I-EGF_1	452..481	CDD:465729	11/33 (33%)
		EGF_2	547..570	CDD:400365	13/24 (54%)
		Integrin_B_tail	620..700	CDD:462325	18/84 (21%)
		Integrin_b_cyt	728..768	CDD:462580	20/39 (51%)