Protein Alignment mys and itgb3

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_002942401.2
• Gene: itgb3 / 100498495
• XenbaseID: XB-GENE-1009964
• Length: 785
• Species: Xenopus tropicalis
• Alignment Length: 857
• Identity: 330/857 - (38%)
• Similarity: 457/857 - (53%)
• Gaps: 102/857 - (11%)

  Fly     9 CQLALLMIAILAAIAGQTDAQKAAKLTAVSTCASK--EKCHTCIQTE-GCAWCMQPDF-KGQSRC 69
            |.|.||::.     ||...|         |.||::  ..|..|:... .||||.|.:| ||..||
 Frog     8 CILQLLLLT-----AGTWGA---------SICATRGVTSCQKCLAVNPQCAWCSQENFGKGAPRC 58

  Fly    70 YQNTSSL---CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSF 131
            ...::.|   |..|....|::..|:..|..|
 Frog    59 DLKSALLSNGCEMENIEFPVSTFQVAENRPL---------------------------------- 89

  Fly   132 YSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKS 196
               |..||       |....||.||.||.:.|.||.::.....:...|.|.||||:|||||||.|
 Frog    90 ---SVKGS-------EGDTREITQISPQKIDLYLRPDDPKVFNLQVRQVEDYPVDIYYLMDLSYS 144

  Fly   197 MEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYV-STIPKKLEHPC----ENCKAPY 256
            |:||..|:.|||..|||.|:|:|:|..:|||:||||.:.||: .:.|:.:::||    ..|...:
 Frog   145 MKDDLIKIQTLGTSLSERMRRLTSNLRIGFGAFVDKPMAPYMFMSPPEVIKNPCYEFHTECMPTF 209

  Fly   257 GYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAG 321
            ||::.:.|.:....|:.||:...||.|.|:|||||||::||..|.::||||.::..||||:|||.
 Frog   210 GYKHILALTDEVTRFNEEVQKQKVSRNRDSPEGGFDAVIQAAVCDNKIGWRNESSHLLVFTTDAR 274

  Fly   322 FHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVY 386
            .|.|.||:|.|::.||||:|||.....|..||..|||||..:.:|:.:..||::||||...||:|
 Frog   275 THIALDGRLAGIVQPNDGKCHLDLNNNYAASTTLDYPSIGLMTEKLSEKNINLVFAVTNEVLSLY 339

  Fly   387 EKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMK-DNATGDVKITYFSSCLSNGPEVQT 450
            .|..|.|.|::...|..|||||::|::..|.||.|.||:: .:...::.:::.:||.::......
 Frog   340 TKYSELIPGTTVGVLSQDSSNVIQLIENSYEKIRSKVELEVRDLPEELSLSFSASCQNDEFTPGL 404

  Fly   451 SKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGY 515
            ..|..||.|..|||:.:.::.:|| ..|:  :|..|.|||..:.:.:.:...|.|.|::     |
 Frog   405 KSCTGLKIGDTVSFSIEAKVRECP-SVRE--KTFTIKPVGFKDSLTVTVHFQCDCACQD-----Y 461

  Fly   516 QVQANS--CS-GHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHC 577
            . |.||  |: |:||..||||.|:..:.|..||||..|...  :....| :.....|.|:.||.|
 Frog   462 D-QPNSTLCNHGNGTLSCGICQCNPGWLGPYCECSEEDYNP--SQQDRC-SPKEGATICNRRGEC 522

  Fly   578 VCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQE 642
            |||.|.||  .|.:..:.||:||||:|||.|.:.::|||  ||.|.||.|.|:..|||..|.|..
 Frog   523 VCGQCVCH--ANDLGKVWGKYCECDDFSCLRYKGEMCSG--HGQCNCGDCICESDWTGHYCNCTT 583

  Fly   643 SNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTG 707
            ..|||| ...|.:|||.|.|.||.|:||  ..|.: |..|||||||...|...|.||:|:.::.|
 Frog   584 RTDTCM-SSSGLLCSGRGQCVCGKCECT--QPGSY-GDTCEKCPTCPDACTFKKGCVECKKFERG 644

  Fly   708 ELKNGDDCARNCTQFVPVGVEKVE--IDETKDEQMCKFFDEDDCKFMFKYSE--QGELHVYAQEN 768
            .......|...|..    .:|.|.  :|..|:...|.:.||:||...|:|.|  .|:..:|....
 Frog   645 PWFEDSSCKHICRD----EIESVNELVDNGKNAVNCTYKDENDCVVRFQYYEDSSGKSVLYVINE 705

  Fly   769 KECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQ 833
            .|||....:|.::|.|:.||:|:||..||:||||.:|||||||.:||:||..|||||..||:||.
 Frog   706 AECPQGPDILVVLMSVMGAILLIGLVALLIWKLLISIHDRREFVKFEEERAKAKWDTAHNPLYKG 770

  Fly   834 ATSTFKNPMYAG 845
            |||||.|..|.|
 Frog   771 ATSTFTNITYRG 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	170/470 (36%)
		Integrin_B_tail	692..775	CDD:462325	25/86 (29%)
		Integrin_b_cyt	803..843	CDD:462580	26/39 (67%)
itgb3	XP_002942401.2	INB	32..456	CDD:197563	170/470 (36%)
		I-EGF_1	458..487	CDD:465729	14/34 (41%)
		VESA1_N	538..>665	CDD:463704	59/136 (43%)
		Integrin_B_tail	629..712	CDD:462325	25/86 (29%)
		Integrin_b_cyt	740..780	CDD:462580	26/39 (67%)