Protein Alignment sub and Klp54D

DIOPT Version :10

• Sequence 1: NP_611260.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001303355.1
• Gene: Klp54D / 47216
• FlyBaseID: FBgn0263076
• Length: 760
• Species: Drosophila melanogaster
• Alignment Length: 632
• Identity: 170/632 - (26%)
• Similarity: 239/632 - (37%)
• Gaps: 208/632 - (32%)

  Fly    55 SDTESEYKYQSSEATEG--------ASCATSAADSSNVETGPQVFLRLRPVKDASK--------- 102
            |...:.|..:|.|...|        ||.:|.:.:.|..|....|.:|:||:.|..|
  Fly   126 SSRNTPYFLRSRENEIGSADTLEIVASKSTGSEECSTPEDNINVVVRVRPLNDKEKRDRHGSTLQ 190

  Fly   103 ----AYIVSEEANVLITSCKVDSTSNNVNRMEKH-------FGFTSIFDSTVGQRDIYDTCVGPK 156
                ..::.|              .|:|.:...|       |.:..:|:....|.||.|.....:
  Fly   191 FPGNGQVILE--------------GNDVGQKRSHNRDSVRVFTYNVVFEPGATQEDILDYSGIKR 241

  Fly   157 IMEE-----ECVTIMTYGTSGSGKTYTLLG-----------DDVRAGIIPRALENIFTIYQDTVF 205
            |:|.     .| |...||.:|||||:||.|           .|.|.|:|               |
  Fly   242 IIEMGIEGFSC-TAFCYGQTGSGKTHTLTGPPDLFVGKPNPKDPRHGLI---------------F 290

  Fly   206 RSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFE-TKASTDVSV 269
            ||           ||                                    ::|: .|...||:.
  Fly   291 RS-----------FL------------------------------------YLFQLIKNRKDVNY 308

  Fly   270 LVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNK--GHVFIKGLTSVFVTSSEEALRL 332
            ::..||:|||||.|.|||       ..|.. ||.|.:..:|  |..|::.|.:|.....::.|.:
  Fly   309 VLKASFMEIYNERVIDLL-------NPGSA-RKPLAVRWSKKSGGFFVENLFTVDCEELDDLLAV 365

  Fly   333 LRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSG----ITTQSSYKFCDLAGSERVNNTGTS 393
            |..|.:.....|.::|.:|||||.:.||.||...::.    ::......|.||||||....|.:.
  Fly   366 LEEGMRNRAVGSHAMNDHSSRSHTILTVHILSDQQTDGGVFLSKHGKINFVDLAGSELTKKTMSE 430

  Fly   394 GLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTP 458
            |..|:||.|||.||||||.|:.:.|  ..||....||||||:||.||..:|.|.....||..|:|
  Fly   431 GKTLEEANNINKSLMVLGYCISSLS--DSKKRTGHIPYRDSQLTKLLADSLAGNGVTLMIACVSP 493

  Fly   459 LDKYYEENLNVLNFASIAKNIIFKEPVIKQ--------------HRVSYCGFMEFSKMSTC---- 505
            ....:.|.||.|.:||.||.|..| ||||.              |.:.    ||...:...
  Fly   494 AHYNHAETLNTLRYASRAKRIRTK-PVIKMDPREALILSLKRDIHALQ----MENDHLKAALNLH 553

  Fly   506 -----EGGDYTKELEDENVRLQL--------------------EIEQLKYDHVLQMQLLE-EKLR 544
                 .||.....||     |||                    |::..:...::::.::| |.||
  Fly   554 HQAAPNGGPVENLLE-----LQLDRVSSGGGVPVPKVDLQRLPELDGSELAELVKLYMVENESLR 613

  Fly   545 ---------RELTATYQEII--QNNK--KQYED---ECEKKLLIAQR 575
                     ||.....|||:  :|.:  |:.||   .|.:..||..|
  Fly   614 QENNHLFTVRETILRDQEIVCRENERLLKKLEDVNKVCVRSPLIPAR 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_611260.1	KISc	89..477	CDD:276812	124/430 (29%)
		GBP_C	<512..603	CDD:293879	23/101 (23%)
		coiled coil	576..586	CDD:293879	170/632 (27%)
		coiled coil	592..603	CDD:293879
Klp54D	NP_001303355.1	KISc	166..520	CDD:214526	129/441 (29%)