Protein Alignment sub and Kif3C

DIOPT Version :10

• Sequence 1: NP_611260.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 154/646 - (23%)
• Similarity: 237/646 - (36%)
• Gaps: 221/646 - (34%)

  Fly    81 SSNVETGPQVFLRLRPVKDASKAYIVSEEANVLITSCKVDSTSNNVNRMEKHFGFTSIFDSTVGQ 145
            |.|:    :|.:|.||:....|.........:...:..|.:.|..::: :|.|.|.|:::.....
  Fly     2 SENI----KVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQ-QKKFIFDSVYNMKTDT 61

  Fly   146 RDIYDTCVGPKIMEEECV------------TIMTYGTSGSGKTYTLLGDD---VRAGIIPRALEN 195
            ..|||         |.|.            ||..||.:|.|||:|:.||:   ...||||:..
  Fly    62 EVIYD---------EMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCF-- 115

  Fly   196 IFTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFE 260
                                                                        ||:||
  Fly   116 ------------------------------------------------------------DHIFE 120

  Fly   261 -TKASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPR--KNLKIVGNKGHVFIKGLTSVF 322
             ...:|:|..|..|:::|||||.:.|||   .|.:....:..  |.|..:|    |.:..||:..
  Fly   121 RISMTTNVRYLALVTYLEIYNERIRDLL---NKNENTNVINHFLKELPGIG----VSVPTLTTQP 178

  Fly   323 VTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDI--------LKYNRSGITTQSSYKFC 379
            |.::.:....|..|.:....|:|.:|.||||||.:||:.:        :..:..|...:......
  Fly   179 VVNANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLV 243

  Fly   380 DLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAAL 444
            |||||||...||..|.|||||..||.||..||..:  :|.|..|  |..:|:||||||.|||.:|
  Fly   244 DLAGSERQRKTGAQGDRLKEASQINLSLSALGNVI--SSLVDGK--AKHVPFRDSKLTRLLQDSL 304

  Fly   445 LGKEKLAMIVTVTPLDKYYEENLNVLNFASIAKNI------------------------------ 479
            .|..|..||..::|.|.:|:|.::.|.:||.||||
  Fly   305 GGNTKTLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQ 369

  Fly   480 --------------IFKEPV-IKQH---------------RVSYCGFMEFSKMSTCEGGDYTKEL 514
                          |.|.|: |.||               |.....|...:.:.|.......:..
  Fly   370 ESQQIINKNNDPNKIIKSPLKIIQHTNMNSTKNVQIIDLGRNCKASFKTNNSILTKPNFPLIQSK 434

  Fly   515 EDENVRLQLEIEQLKY-----DHVLQMQLLEEKLRRELTAT------------------------ 550
            |:..::.:..|:.:|.     :.:...:|.|:.:.|:..|.
  Fly   435 EEVQLQARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSRVKCEDRDLLQGH 499

  Fly   551 YQEIIQ--NNKKQYEDECEKKLLIAQRE-----SEFMLSSQRRRYEEQIEDLKDEIEELKN 604
            |..|.|  :.|..|..:|::|:.:.:.|     |||.|            |.:|.::|::|
  Fly   500 YATITQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQL------------DREDYLDEIRN 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_611260.1	KISc	89..477	CDD:276812	116/413 (28%)
		GBP_C	<512..603	CDD:293879	22/126 (17%)
		coiled coil	576..586	CDD:293879	5/14 (36%)
		coiled coil	592..603	CDD:293879	3/10 (30%)
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	119/422 (28%)