DRSC/TRiP Functional Genomics Resources

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Protein Alignment sub and ncd

DIOPT Version :10

Sequence 1:NP_611260.1 Gene:sub / 44870 FlyBaseID:FBgn0003545 Length:628 Species:Drosophila melanogaster
Sequence 2:NP_476651.1 Gene:ncd / 43517 FlyBaseID:FBgn0002924 Length:700 Species:Drosophila melanogaster


Alignment Length:440 Identity:112/440 - (25%)
Similarity:185/440 - (42%) Gaps:103/440 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 TESEYKYQSSEATEGASCATSAADSS-----------NVETGPQVFLRLRPVKDASK-----AYI 105
            ||...:....:|.|..:|......|:           ::....:||.|:||..::.:     .:.
  Fly   307 TEELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWT 371

  Fly   106 VSEEANVLITSCKVDSTSNNVNRMEKHFGFTSIFDSTVGQRDIYDTCVGPKI---MEEECVTIMT 167
            ..:|:.|.:.|....:.|....::   |.|..:|.....|.||:: .|.|.|   ::...:.|..
  Fly   372 YHDESTVELQSIDAQAKSKMGQQI---FSFDQVFHPLSSQSDIFE-MVSPLIQSALDGYNICIFA 432

  Fly   168 YGTSGSGKTYTLLGDDVRAGIIPRALENIFTIYQDTV--FRSPKLKLINGSIVFLQDDASLKELQ 230
            ||.:|||||||:.|.....|:|||.::.:|    |::  :|:...:                   
  Fly   433 YGQTGSGKTYTMDGVPESVGVIPRTVDLLF----DSIRGYRNLGWE------------------- 474

  Fly   231 IRKKLLDLCPDISAHHQRLKQVIDGDHMFETKASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDK 295
                                        :|.||          :|:|||||::||||:...|..:
  Fly   475 ----------------------------YEIKA----------TFLEIYNEVLYDLLSNEQKDME 501

  Fly   296 LGEVPRKNLKIVGNKGHVFIKGLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTV 360
            :...  ||     ||..:::..:|...|........|:...:.....|||:.|..|||||.|..:
  Fly   502 IRMA--KN-----NKNDIYVSNITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKL 559

  Fly   361 DIL-KYNRSGITTQSSYKFCDLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKK 424
            ::: ::......:..|....||||||    :..:..|:.|.||||.||..|...:  .:.:||: 
  Fly   560 ELIGRHAEKQEISVGSINLVDLAGSE----SPKTSTRMTETKNINRSLSELTNVI--LALLQKQ- 617

  Fly   425 NADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNVLNFAS 474
              |.||||:||||.||..:|.|..|..|.:.|:|....::|::..|.||:
  Fly   618 --DHIPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAA 665

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
subNP_611260.1 KISc 89..477 CDD:276812 106/397 (27%)
GBP_C <512..603 CDD:293879
coiled coil 576..586 CDD:293879
coiled coil 592..603 CDD:293879
ncdNP_476651.1 PRK03918 <204..350 CDD:235175 6/42 (14%)
KISc_C_terminal 346..672 CDD:276817 106/401 (26%)
Blue background indicates that the domain is not in the aligned region.

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