Protein Alignment sub and Klp59D

DIOPT Version :10

• Sequence 1: NP_611260.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_611762.1
• Gene: Klp59D / 37674
• FlyBaseID: FBgn0034827
• Length: 729
• Species: Drosophila melanogaster
• Alignment Length: 656
• Identity: 174/656 - (26%)
• Similarity: 256/656 - (39%)
• Gaps: 176/656 - (26%)

  Fly    25 IDRRFRPRPNKKMRLFDNIQESEEESFSEYSDTESEY-----KYQSSEATEGASCATSAADSSNV 84
            ::|....|..::.|..:.:||.:....:...:...|.     :|:|:.......|.     ..|.
  Fly   169 VNRMKEQREKRRARQAEQLQEKDALRRNNPGNPNWEVSVMLRQYRSTLIFSPLRCL-----DPNG 228

  Fly    85 ETGPQ--VFLRLRPV---KDASK--AYIVSEEANVLIT---SCKVDSTSNNVNRMEKH-FGFTSI 138
            .|..|  |.:|.||:   ::.||  ..|....|:.||.   ..|||.|    ..:|.| |.|...
  Fly   229 GTVQQITVCVRKRPMSRKEENSKNLDIITVPSADSLIVHELRLKVDLT----KFLEHHKFRFDYT 289

  Fly   139 FDSTVGQRDIYDTCVGPKI---MEEECVTIMTYGTSGSGKTYTLLGD------DVRAGIIPRALE 194
            ||.......:||....|.|   .|....|...||.:|||||:|:.|:      |...||...|..
  Fly   290 FDEECSNALVYDHTARPLIRTMFEGGNATCFAYGQTGSGKTHTMGGEFFGKVQDCGTGIYAMAAR 354

  Fly   195 NIFTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMF 259
            ::|    :.|.| |:.:.:...|.                    |
  Fly   355 DVF----EEVSR-PEYRQMGAKIT--------------------C-------------------- 374

  Fly   260 ETKASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRK-NLKIVGN-KGHVFIKGLTSVF 322
                          ||.|||...|:|||           :|.| .|:::.: :..|.:.|||.:.
  Fly   375 --------------SFFEIYGTKVFDLL-----------LPNKPMLRVLEDARQQVVVVGLTEMP 414

  Fly   323 VTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQSSYKFCDLAGSERV 387
            ||..|:.|||:..|.:..|...||.||.|||||.||.:.:...:..|  ......|.||||:||.
  Fly   415 VTKVEDVLRLIEHGSKERTSGQTSANAKSSRSHAVFQIALHFPDSWG--PHGKCSFVDLAGNERG 477

  Fly   388 NNTGTSGLRLK-EAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLG--KEK 449
            .:|.::..:.: |...||.||:.|..|:.|.|     :.:..:|:|.||||.:|:.:.:|  |.|
  Fly   478 ADTQSADRQTRIEGAEINKSLLALKECIRALS-----RQSSHLPFRGSKLTQVLRDSFVGGKKNK 537

  Fly   450 LAMIVTVTPLDKYYEENLNVLNFASIAKNIIFKEPVIKQHRVSYCGFMEFS---------KMSTC 505
            ..||..::|.....|..||.|.:|...|.:|.||   .:|..|..|..|.|         :|...
  Fly   538 TCMIAMISPSMSCVENTLNTLRYADRVKELIAKE---DEHLQSVEGDGEKSPDLNEESEPEMMAD 599

  Fly   506 EGGDYTKELEDE-NVRLQLEIEQ----------LKYDHVL----------------QMQLLEEKL 543
            |.||  :|.||| |..|.:..|:          :.::|.|                |..||.|.|
  Fly   600 EEGD--EEPEDEDNQHLTISSEEASSYNNMSYDMSFNHTLNILGPSRNVDIQEVAEQHALLVENL 662

  Fly   544 R------RELTATYQEIIQNNKKQYEDECEKKL--LIAQ----RESEFMLSSQRRRYEE-QIEDL 595
            .      |:| .|.:||     :||....|..|  |:|.    |:.....::|:...|| |....
  Fly   663 ETYAHNFRQL-KTDKEI-----EQYTQNSESALMKLLAMVNRTRDVTHNYNTQKLLKEENQNAYK 721

  Fly   596 KDEIEE 601
            |.|::|
  Fly   722 KGELDE 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_611260.1	KISc	89..477	CDD:276812	117/412 (28%)
		GBP_C	<512..603	CDD:293879	33/130 (25%)
		coiled coil	576..586	CDD:293879	1/9 (11%)
		coiled coil	592..603	CDD:293879	3/10 (30%)
Klp59D	NP_611762.1	KISc_KIF2_like	233..565	CDD:276818	117/412 (28%)