Protein Alignment sub and klp9

DIOPT Version :10

• Sequence 1: NP_611260.1
• Gene: sub / 44870
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001342762.1
• Gene: klp9 / 2539778
• PomBaseID: SPBC15D4.01C
• Length: 633
• Species: Schizosaccharomyces pombe
• Alignment Length: 604
• Identity: 169/604 - (27%)
• Similarity: 283/604 - (46%)
• Gaps: 110/604 - (18%)

  Fly    89 QVFLRLR---PVKDASKAY---IVSEEANVLITSCKVDSTSNNVNR---MEKHFGFTSIFDSTVG 144
            |:|||::   |..|||..|   .|..:..:|:.|.: ||.:..|::   :|| ..||.:|..:..
pombe     3 QIFLRVKKAQPSSDASNKYGFLTVLNDYEILLESPE-DSHAYRVSKSKTLEK-ASFTKVFPPSCT 65

  Fly   145 QRDIYDTCVGPKIMEE----ECVTIMTYGTSGSGKTYTLLGDDVRAGIIPRALENIFTIYQ---- 201
            |.|::.|...|.|.:.    ....:.|.|.||:||||||.|...|.|:...||:.:|...:
pombe    66 QLDVFSTICAPLIADSLVNMNDTLLFTLGVSGAGKTYTLFGPSDRPGVAFLALDALFYAIKGREA 130

  Fly   202 --DTV--FRS--PKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFE 260
              .||  .||  .|.|::..| .||:.:|.| ::::        |:...:.....::.:.::.:
pombe   131 SPQTVEFLRSQLEKCKIVEAS-KFLRGEAPL-DIKV--------PNTEYYASHFPKIEEKNYQY- 184

  Fly   261 TKASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNKGHVFIKGLTSVFVTS 325
                     .:::||.||||:.::|||   .|....|.....:||.........|.|:..|||::
pombe   185 ---------AIYLSFAEIYNDRIFDLL---EKASFFGHRHALSLKKSSTSDKKSIAGIQKVFVSN 237

  Fly   326 SEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQSSYKFC-----DLAGSE 385
            :.||.:|::...|.....||..|:.|||||.:.::::.|.    .|..:.::.|     ||||||
pombe   238 TTEAYKLIQKVLQLRKSTSTKSNSVSSRSHLIMSIELFKV----CTKSNKFESCQIDLVDLAGSE 298

  Fly   386 RVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLL--QAALLGKE 448
            |..:..||||.|:|..:||.||:.||:||:|.....:.|. .|||:|.||||.||  ...|.|..
pombe   299 RTRSAETSGLLLREGASINRSLLTLGQCLEALRRKHEGKQ-HIIPFRQSKLTELLFHSGHLSGLA 362

  Fly   449 KLAMIVTVTPLDKYYEENLNVLNFASIAKNIIFKEPVIKQHRVSYC---GFMEFSK--MSTCEGG 508
            .:.|:|.:.|... ::||..|:.:::.|:.|:  .|.:.::..|..   ..::.||  .||....
pombe   363 GINMLVNIDPFGS-FDENAQVMRYSANAREIL--PPPLNENSGSQSPSHSLLQKSKNTSSTKALT 424

  Fly   509 DYTKELEDENVRLQL-------EIEQLKYDHVLQM-QLLEEKL----RRELTATYQEIIQN---- 557
            .:.::|:.||.:|::       |:..|:|:...|| :.:||::    |..||...:|..|.
pombe   425 SHLEQLQQENQQLRMLLADADSEMMNLEYEIRQQMTREMEERVSEVERTFLTKLLEESAQGIEYT 489

  Fly   558 ----------NKKQYEDECEKKLLIAQRESEFMLSSQRRRYEEQIEDLKDEIEELKNPASDTDIS 612
                      .||..::..||...|||             .|:.||:|.:|:..|:..:.....:
pombe   490 DQKLEKMGGWMKKLQDENSEKTETIAQ-------------LEQIIEELHEELRSLEEESIKESSA 541

  Fly   613 DDPNES---KSPIEILDDD 628
            ...||:   :|..::|.:|
pombe   542 TQQNENQHKRSSRKLLYED 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_611260.1	KISc	89..477	CDD:276812	127/417 (30%)
		GBP_C	<512..603	CDD:293879	28/116 (24%)
		coiled coil	576..586	CDD:293879	0/9 (0%)
		coiled coil	592..603	CDD:293879	4/10 (40%)
klp9	NP_001342762.1	KIP1	40..633	CDD:227392	156/566 (28%)