Protein Alignment: sub and zen-4

• Sequence 1: NP_001286548.1
• Gene: sub
• FlyBaseID: FBgn0003545
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001023312.2
• Gene: zen-4
• WormBaseID: WBGene00006974
• Length: 787
• Species: Caenorhabditis elegans
• Alignment Length: 582
• Identity: 169/583 (29%)
• Similarity: 271/583 (46%)
• Gaps: 114/583 (20%)

  Fly    77 SAADSSNVETGPQVFLRLRPVKDASKAYIVSEEANVLITSCKVDSTSNNVNRMEKHFGFTSIFDS 141
            |..::.::|    |..||.|...::.:.|..:|.::............|..::||.|.|..:|..
 Worm    21 SIEETDSIE----VVCRLCPYTGSTPSLIAIDEGSIQTVLPPAQFRRENAPQVEKVFRFGRVFSE 81

  Fly   142 TVGQRDIYD-TCVG--PKIMEEECVTIMTYGTSGSGKTYTLLG--DDVRAGIIPRALENIFTIYQ 201
            ..||..::: |.|.  ..:::.:...:.|||.:|||||||:.|  .:...|::||.|
 Worm    82 NDGQATVFERTSVDLILNLLKGQNSLLFTYGVTGSGKTYTMTGKPTETGTGLLPRTL-------- 138

  Fly   202 DTVFRSPKLKLINGSI---VFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVID--------G 255
            |.:|.|     ||..:   :|.  .::|...:||..|       .||.:|.:...|        .
 Worm   139 DVIFNS-----INNRVEKCIFY--PSALNTFEIRATL-------DAHLKRHQMAADRLSTSREIT 189

  Fly   256 DHMFET-KAS---TDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIV-------GN 309
            |...|. |.|   .|:...|:|::|||||...||||          |..|...:::       ..
 Worm   190 DRYCEAIKLSGYNDDMVCSVFVTYVEIYNNYCYDLL----------EDARNGSRVLTKREIRHDR 244

  Fly   310 KGHVFIKGLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQS 374
            :..:::.|...|.|:||||||.:..||::|...:||.:|.:|||||.|||:.::...|: ..|:|
 Worm   245 QQQMYVDGAKDVEVSSSEEALEVFCLGEERRRVSSTLLNKDSSRSHSVFTIKLVMAPRA-YETKS 308

  Fly   375 SY-----------KFC--DLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQK--KK 424
            .|           :.|  |||||||...|...|.||.||.:||.|||.|.:|::.....||  .:
 Worm   309 VYPTMDSSQIIVSQLCLVDLAGSERAKRTQNVGERLAEANSINQSLMTLRQCIEVLRRNQKSSSQ 373

  Fly   425 NADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNVLNFASIAKNIIFKEPV--IK 487
            |.:.:|||.||||.|.:..|.|..|:.|::.|.|....|:||::.|.||..::.|..|:.|  :.
 Worm   374 NLEQVPYRQSKLTHLFKNYLEGNGKIRMVICVNPKPDDYDENMSALAFAEESQTIEVKKQVERMP 438

  Fly   488 QHRVSYCGFMEFSKMSTCEGGDYTKELEDENVRLQLEI---------EQLKYDHVLQMQLLEEKL 543
            ..|:.:..|.:::  |..:|   :..:||:..|   ||         :....|.|..|.    |.
 Worm   439 SERIPHSFFTQWN--SELDG---SVRMEDDGSR---EIPCPPTFCLTDCNDKDTVDSMY----KY 491

  Fly   544 RRELTATYQEIIQNNKKQYEDECEKKLLIAQRESEFMLSSQRRRYE-EQIED-LKDEIEELK 603
            .|:|::     :||:.   |:.....||...|  ::|:.:..:|.| .:::| |.|:.||:|
 Worm   492 ARKLSS-----LQNSS---EEGPSSTLLTMIR--QYMMEADYQRVEIARLKDSLNDKDEEIK 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sub	NP_001286548.1	KISc	89..477	CDD:276812	134/430 (31%)
		Kinesin	93..479	CDD:278646	133/428 (31%)
		GBP_C	<512..603	CDD:303769	25/102 (25%)
		coiled coil	576..586	CDD:293879	1/10 (10%)
		coiled coil	592..603	CDD:293879	5/12 (42%)
zen-4	NP_001023312.2	Motor_domain	26..426	CDD:277568	135/437 (31%)
		KISc	27..434	CDD:214526	137/444 (31%)
		MKLP1_Arf_bdg	674..>748	CDD:293148

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E2759_KOG0247
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D314538at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R641
TreeFam	0	0.000	Not matched by this tool.
	3	2.940