Protein Alignment sad and cyp27b1

DIOPT Version :10

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001006907.1
• Gene: cyp27b1 / 448754
• XenbaseID: XB-GENE-942527
• Length: 506
• Species: Xenopus tropicalis
• Alignment Length: 497
• Identity: 125/497 - (25%)
• Similarity: 216/497 - (43%)
• Gaps: 78/497 - (15%)

  Fly    64 GLPVVGTLVDLIAAGGATHLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYP 128
            |...|..:.||....|...||:.......::||:::...|... .|.|:..:|:..|.:.||::|
 Frog    46 GPSTVSFISDLFCRRGLARLHELQLEGKAKFGPVWKASFGPIL-TVHVAEPSLIEQVLRQEGKHP 109

  Fly   129 QHPLPDAWTLYNQQHACQRGLFFMEGAEWLHNRRILNRLLLNGNLNWMDVHIESCTRRMVDQWKR 193
            ......:|..|.|......||...||.||...|.||.:.:|                      |.
 Frog   110 IRSDLSSWKDYRQCRGHSYGLLTAEGEEWQQFRSILGKHML----------------------KP 152

  Fly   194 RTAEAAAIPLAE-SGEI-------RSYE----LPLLEQQLYRWSIEVLCCIMFGTSVLTC--PKI 244
            :..||.:..|.: .|::       ||..    :..:.::.|.:.:|.:..::| .|.:.|  |.:
 Frog   153 KEVEAYSDVLNDVVGDLIKKINYQRSQNQNNVVKDIAKEFYMFGLEGISSVLF-ESRIGCLEPTV 216

  Fly   245 QSSLDYFTQIVHKVFEHSSRLMTFPPRLAQILRLPIWRDF-----------EANVDEVLREGAAI 298
            ....:.|.|.::.:|..:...|..|..|.:|.|.| |:.|           :.::|:.:::.|..
 Frog   217 PKETEKFIQSINTMFVMTLLTMAMPKFLHKIFRKP-WQKFCESWDYMFAFAKGHIDKRMKDVAQK 280

  Fly   299 IDHCIRVQEDQRRPHDEALYHRLQAADVPGDMIKRIFVDLVIAAGDTTAFSSQWALFALSKEPRL 363
            :....:|:       .:.|.:.|....:|...|.....:|::|..||.:.:..|:|:.|::.|.:
 Frog   281 LAQGEKVE-------GKYLTYYLAQEKIPMKSIYGNVTELLLAGVDTISSTLSWSLYELAQHPDI 338

  Fly   364 QQRLAKE-----------RATNDSR--LMHGLIKESLRLYPVAPFIGRYL-PQDAQLGGHFIEKD 414
            |..:..|           ..::.:|  |:..::||.||||||.|...|.: .:|.|:|.:.|.|.
 Frog   339 QSAVYSEVEEILQGKQIPSPSDVARMPLLKAVVKEVLRLYPVIPGNARVVADRDIQVGDYIIPKK 403

  Fly   415 TMVLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVHKSHGSLPFAIGQRSCIGRRVALKQLHSL 479
            |::.|..|...||.:.|..|....|:||.  :.|..|..:.||||..|:|||||||:|..:::..
 Frog   404 TLITLCHYATSRDENVFSNPNEFQPDRWL--KKEDTHHPYASLPFGFGKRSCIGRRIAELEVYLA 466

  Fly   480 LGRCAAQFEMSCLNEMPVDSVL---RMVTVPDRTLRLALRPR 518
            |.|..:.||:.  .|.|...|:   |.:.||::.:.|....|
 Frog   467 LARILSHFEVK--PEQPGSLVMPMTRTLLVPEKEINLQFLER 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	116/462 (25%)
cyp27b1	NP_001006907.1	CYP27B1	72..501	CDD:410741	116/464 (25%)