Protein Alignment sad and Cyp312a1

DIOPT Version :9

• Sequence 1: NP_650123.1
• Gene: sad / 44858
• FlyBaseID: FBgn0003312
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_649030.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 566
• Identity: 124/566 - (21%)
• Similarity: 201/566 - (35%)
• Gaps: 168/566 - (29%)

  Fly    25 ILSLSLF-------RSRCDPPPLQRFPATELPPAVAAKYVPIPRVKGLPVVGTLVDLIAAGGAT- 81
            :|:|||:       :||.| ....::||   |||       :|.:..|.::..||.......||
  Fly    10 LLALSLYLLYVFERQSRID-RLTHKWPA---PPA-------LPFIGHLHILAKLVGPHPLRRATE 63

  Fly    82 ----HLHKYIDARHKQYGPIFRERLGGTQDAVFVSSANLMRGVFQHEGQYPQHPLPDAWTLYNQQ 142
                |||   |.|.|.:        .||:  :::...|            |:    |...|.:.|
  Fly    64 MINEHLH---DHRAKLW--------MGTK--LYLVDCN------------PK----DIQALCSAQ 99

  Fly   143 HACQR-------------GLFFMEGAEWLHNRRILNRLLLNGNLNWMDVHIESCTRRMVDQW--- 191
            ...|:             |||.....:|.|.|:|:               :.:....|:.|:
  Fly   100 QLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKIV---------------MPAFNYTMIKQFVAV 149

  Fly   192 ---KRRTAEAAAIPLAESGEIRSYELPLLEQQLYRWSIEVLCCIMFGTSVLTCPKIQSSL--DYF 251
               :.|.........||||:    ::..| |.:..::::.:|....|.||.:    |||.  :|.
  Fly   150 FEKQSRILLTNVAKFAESGD----QIDFL-QLISCFTLDTICETALGVSVGS----QSSAKSEYL 205

  Fly   252 TQIVHKVFEHSSRLMTFPPRLAQILRLPIWRDFEAN------------VDEVLREGAAIIDHCIR 304
            ..:       .|.|:....||..|        |..|            ..|:::......:..|:
  Fly   206 DAV-------KSILVIIDKRLKNI--------FYRNSFIFKRTSHYKREQELIKTLHGFTEGIIQ 255

  Fly   305 VQEDQRRPHDEALYHRLQAADVPGDMIKRIF-------------------------VDLVIAAG- 343
            .:.|:  .:.:|.....|::|...|.:||..                         ||.:|..|
  Fly   256 KRIDE--INQDAENRNYQSSDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGF 318

  Fly   344 DTTAFSSQWALFALSKEPRLQQRLAKE---------------RATNDSRLMHGLIKESLRLYPVA 393
            |.||.:..:.::.::..|..|||..:|               ........:...|||:||:||..
  Fly   319 DLTATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSG 383

  Fly   394 PFIGRYLPQDAQLGGHFIEKDTMVLLSLYTAGRDPSHFEQPERVLPERWCIGETEQVHKSHGSLP 458
            |...|....:..:...||.|.:.|::|....||....|..|....|:||.||...:: ::...:|
  Fly   384 PLTARKATANCTINDFFIPKGSDVIISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKI-EATTFIP 447

  Fly   459 FAIGQRSCIGRRVALKQLHSLLGRCAAQFEMSCLNEMPVDSVLRMV 504
            |..|.|||:|:|.|:..|..:|......|....|.|..|...|..|
  Fly   448 FMAGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sad	NP_650123.1	CYP24A1-like	91..512	CDD:410677	101/488 (21%)
Cyp312a1	NP_649030.1	CYP4	75..504	CDD:410721	101/487 (21%)