DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment m and AgaP_AGAP003012

DIOPT Version :9

Sequence 1:	NP_572747.1	Gene:	m / 44835	FlyBaseID:	FBgn0002577	Length:	682	Species:	Drosophila melanogaster
Sequence 2:	XP_311867.4	Gene:	AgaP_AGAP003012 / 1272942	VectorBaseID:	AGAP003012	Length:	695	Species:	Anopheles gambiae

Alignment Length:	367	Identity:	77/367 - (20%)
Similarity:	137/367 - (37%)	Gaps:	84/367 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 LEVMCGKDHMDVHLTFSHPFEGIVSSKGQHSDPRCVYVPPSTGKTFFSFRISYSRCGTKPDLNGQ 115
            :.|.|....:.|.:..:.||.|.:.:.|:........:...|      ||:..:..|  .|.|.|
Mosquito   357 VSVHCKDTRIAVQVRTNKPFNGRIYALGRSETCNIDVINSDT------FRLDLTMGG--QDCNTQ 413

  Fly   116 ----FYENTVVVQYDKDLLEVWDEAKRLRCEWFNDYEKTASKPPMVIADLDVIQLDFRGDNVDCW 176
                .|.||||:|:...::...|:..:::|. ::...|..|...:.|.|.::|.::
Mosquito   414 SATGIYSNTVVLQHHSVVMTKADKIYKVKCT-YDMSSKNISFGMLPIRDPEMIHIN--------- 468

  Fly   177 MEIQHGKGPWAPPVS-----------GIVPLGSTLTLVVAINDYRGEFDMRVKSCVA-SDGSGHV 229
                  ..|.|||..           ..|.:|..||..:.|.: ...:.:..:|||| :..|...
Mosquito   469 ------SSPEAPPPRIRILDARAREVETVRIGDRLTFRIEIPE-DTPYGIFARSCVAMAKDSKST 526

  Fly   230 INLSDEFGCVLRPKMISRFLKARAPDERATVITYAFFHAFKFPDALSVHIKCKVEICRHGCLDHC 294
            ..:.|:.||.:.|.:...|.:    |..|   ..:.:.||:|.::..|..:|.|:.|...|
Mosquito   527 FQIIDDDGCPVDPTIFPAFTQ----DGNA---LQSIYEAFRFTESYGVIFQCNVKYCLGPC---- 580

  Fly   295 QNTGVGGGGGGSGESLGLGLGLGLTNANERKDVHMSDALGSSSNDLLRDLALPPGGQHGMGMGMG 359
             ...|...|..|.||.|          .:|:.|       ::|||.:.:.......|..:.:..|
Mosquito   581 -EPAVCEWGRDSVESWG----------RKRRSV-------TASNDTVEEEEDMNISQEILVLDFG 627

  Fly   360 PDHDIFYEDIIHDHKQTLGGGGMPAGGDYGHEKSVN-LQPRP 400
            .:.:   .|.:.....|          |:|.:|:|. ::|.|
Mosquito   628 DEKN---RDFLRSEAST----------DFGRDKTVTIIEPCP 656

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
m	NP_572747.1	ZP	55..286	CDD:214579	53/246 (22%)
m	NP_572747.1	Zona_pellucida	<194..287	CDD:278526	23/93 (25%)
AgaP_AGAP003012	XP_311867.4	PAN_4	35..86	CDD:290993
		PAN_AP_HGF	119..199	CDD:238532
		PAN_1	224..315	CDD:278453
		ZP	360..576	CDD:214579	53/247 (21%)
		Zona_pellucida	<490..583	CDD:278526	25/105 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X161
TreeFam	0	0.000	Not matched by this tool.
	2	1.910