|
Fly 7 EKRPLKRTRLGPPDIYPQDAKQREDELTPTNVKHGFTTTPPLS-DEFGTAHNSNVNASKVSAFFS 70
|:|||||.||||||:||||.||:|||||..|||.||...|..: ||.|:|.|..:|.||:.|:||
Rat 10 EQRPLKRPRLGPPDVYPQDPKQKEDELTAVNVKQGFNNQPAFTGDEHGSARNIVINPSKIGAYFS 74
Fly 71 GVLAKKEELMTLPDTGRKKQQINCKDNFWPVSPRRKCTVDAWFKDLAGNKPLLSLAKR------- 128
.:||:|.:|.|..|||:||.|:|.|||:|.|:.|.:..:.:||.||||||||..|||:
Rat 75 SILAEKLKLNTFQDTGKKKPQVNAKDNYWLVTARSQSAIHSWFSDLAGNKPLAILAKKELPLAKS 139
Fly 129 ----APSFNKKEEIFITLCENQVNMQRATWFIKLSAAYTLSFTESKNKKRSIYDPAAEWTGNMIK 189
.|..:|||::|..|.:..|.|.||||.||::.||..:.:|:|.|||...||..|||....:
Rat 140 GVPQVPILSKKEDVFAYLAKYSVPMVRATWLIKMTCAYYSAISEAKIKKRQAPDPNLEWTQISTR 204
Fly 190 FMKELLPKLQEYYQQNHDKSSSNGTTSGSLTAAGNGPASNGSTGTSSINSVTGSSASTNVIPVPS 254
:::|.|.|:.::| |..||: |:||.
Rat 205 YLREQLVKISDFY---HMASST-----------GDGPV--------------------------- 228
Fly 255 MASPLPPIHSPANGQQAAPGGGVNAGSVMPTTGSLGGVVGGPGSSVVGGAAGAGAAVPPGSTISG 319
|:||
Rat 229 ---PVPP---------------------------------------------------------- 232
Fly 320 IGSQFEDSRNALKYWKYCHQLSKYMYEESLLDRQEFLNWILDLLDKMRTQASFDEPLKKLVLSFA 384
:...|:|.|:|..:|:.:|::|.:|::.|:|:||||:|:|:| ..|:.|.||:|...
Rat 233 ------EVEQAMKQWEYNEKLAFHMFQEGMLEKHEYLSWILDVLEKIR---PVDDSLLKLLLPLM 288
Fly 385 LQYMHDFVQSERLCRKMAYIVSKKLAQLLNTVVEQQTIKELDEPKL------------------- 430
|||..:||||..|.|::||..:::|:.||: |.|.|
Rat 289 LQYSDEFVQSAYLSRRLAYFCARRLSLLLS-----------DSPNLLAAHSPHMIIGANNTSIGT 342
Fly 431 --------QQDPYELALQEQMSCPHHRDIVLYLSTILQIITIECPTALVWSGIAAHRAPSSLLGS 487
...|.:||..:.:||..|..:|..||.:||.:|:.||:||||: .:.:....:..||
Rat 343 PSPGTPGPGMSPVQLAFSDFLSCAQHGPLVYGLSCMLQTVTLCCPSALVWN-YSTNENKIANPGS 406
Fly 488 PLDHLPLAPSVLPMPTRCPRTNHEIRRQLRAAESDIVLRTQHAEQRWFAAKW--LSAGKNQYTSV 550
|||.|.:|||.||||......|.::|.::...|..|..|.:..|.||...|. .:||.. .:.|
Rat 407 PLDLLQVAPSSLPMPGGNTAFNQQVRARIYEVEQQIKQRGRAVEVRWSFDKCQESTAGVT-ISRV 470
Fly 551 LATLDHLDTHCFDRMEHNNSIDTLYAQIFPSPTVSRRREEDQVEPRPPYEPKQDKDTVRILCEWA 615
|.||:.||.|||||.:.:||::|||.:|| ..::.::..:|.| .|:..|.:|||||
Rat 471 LHTLEVLDRHCFDRTDSSNSMETLYHKIF---WANQNKDNQEVAP-------NDEAVVTLLCEWA 525
Fly 616 VSGQRWGEHRAMVVAILLDKRQIDVTSTPADQQSSDKDDKDSLASGAGLIDGLPVFQHVLMHFLD 680
||.:|.|:||||.||.||:|||.:|.:.... :|...|:|:|::|.:.....|||||:||:.|||
Rat 526 VSCKRSGKHRAMAVAKLLEKRQAEVEAERCG-ESEVLDEKESISSASLAGSSLPVFQNVLLRFLD 589
Fly 681 HDAPVLDEHVSSPQQRTEFTNLVQLFSALIRHDVFSHNAYMHTLISRGDLLLESVLVIKSGTTAT 745
..||.|.: .:|..::.||.|||.||...||||||||:|||.||||||||.:.:...::|
Rat 590 TQAPSLSD-PNSECEKVEFVNLVLLFCEFIRHDVFSHDAYMCTLISRGDLSVTASTGLRS----- 648
Fly 746 KTSPPPPAPPPTTTHGFDDD-------------GFGGGLDFKHNEFDDSNVDDDLDKLVQNIKEK 797
||...:..|...|. |.|.|.....:|.|.|:...|.
Rat 649 ------PAGENSDEHYSKDHEMKMEEHAVMAHMGLGSGTTNIFDEVDKSDFKSDF---------- 697
Fly 798 GQQHEAPDSPKIGP-PGDGETNPGGSIS----------------------------RHYVYTKHF 833
..:.|...| ||:...|...|:| ||..|..||
Rat 698 -----GSEFPIFSPMPGESCENINPSLSRRMSGNGEKLGKREKPRELIFPSNYDLLRHLQYATHF 757
Fly 834 PIPQDDPSMSSYSSESNQRYILLFGVGKERDEKKHAVKKMSKEIGKLFTKKFSIDVAAAGHVKKH 898
|||.|:.| |.|.|||.|||:||||||||.:|.:||::|:|.|:..||.:.:.......:|.
Rat 758 PIPLDESS----SHECNQRTILLYGVGKERDEARHQLKKITKDILKILNKKSTTESGVGDEGQKA 818
Fly 899 SRNEFNF----EATTSKCQQMAYFDQHVVTAQCAANVLEQLNGFALGNNNYLPVQEHVAFLFDLM 959
.:|:... |...:|.|.::|||||.||:|.:.|||||:..||.|.:.:||:..|:..:||||
Rat 819 RKNKQEVFPTPENVFTKLQLLSYFDQHQVTSQISNNVLEQITSFASGTSYHLPLAHHIQLIFDLM 883
Fly 960 ELALNIYSLLELCDSLLKELPEVEHQLQLKKSNLVRSYTTSLALYIVSILRRYHSCLLLSPEQTL 1024
|.||||..|::....||.||..||.:|.||.|:|..||||.|.:.||::||||||||:|:|:||.
Rat 884 EPALNINGLIDFAIQLLNELSVVEAELLLKSSSLAGSYTTGLCVCIVAVLRRYHSCLILNPDQTA 948
Fly 1025 SVFEGVCRTIRHVSNPSECTSAERCIIAYLSDLHESCVLLQGKEQSTEYYQQL---QCIKRFKDI 1086
.||||:|..::||.|||||:|.||||:|||.||:.||..|:.| :..| .|.|..:.|
Rat 949 QVFEGLCGVVKHVVNPSECSSPERCILAYLYDLYVSCSHLRSK------FGDLFSSACSKVKQTI 1007
Fly 1087 FNT--PEQLDLPPQGYNPLLLQELFMAPRRGGKLDPHWLG-TLHESPANVYSFVSNALIAVCR-E 1147
:|. |...:| .::|..:.:....| ....::...|| .|:::.||.||||.|.|:.||. .
Rat 1008 YNNVMPANSNL---RWDPDFMMDFIENP-SARSINYSMLGKVLNDNAANRYSFVCNTLMNVCMGH 1068
Fly 1148 TDNERLNDVALACAELTASCNVLSEEWIYALQSLCSGSKSPRYPHLGG------QVDIGQLKTHN 1206
.|..|:||:|...:||||.|.|||.||:..|::||..|. |:.| .||:..|..|:
Rat 1069 QDAGRINDIANFSSELTACCTVLSSEWLGVLKALCCSSN-----HVWGFNDVLCTVDVSDLSFHD 1128
Fly 1207 ALAVFVCILVARHCFSLADFVSKFALPTLARSVSAGGAELSVDAEAGARLTCHLVLKLFKTLEIP 1271
:||.|:.||:||.||||.|.|...|||:|. :.:.|.| |||.|||:||.|:|.||:. |
Rat 1129 SLATFIAILIARQCFSLEDVVQHVALPSLL-AAACGDA----DAEPGARMTCRLLLHLFRA---P 1185
Fly 1272 QPGMYSVST-SPNPLHAVGNDFSIRLSCDRHLLVGAHKTIPIAAVLAVLKAILIVVDNAALKTPL 1335
|...:..:| .|.| .||.|||||||..||.:|.:.||.||||||:::
Rat 1186 QACFFPQATGKPFP--------GIRSSCDRHLLAAAHNSIEVGAVFAVLKAIMML---------- 1232
Fly 1336 ASGSGTSSGGLGGAFGSGKRSGFNTPVHPGSTPKSNEQRPADLSQILGTSDLQLGSSLTSEPEAL 1400
|..|....|. :|.|:.:.....|.:. |:::....:|..|:|..
Rat 1233 ---------------GDAKIGSNNV-----NTLKNEDFSMRGLRRD-GSAEDAWATSQNSKPYG- 1275
Fly 1401 QQPSVGGMEQISLLEFAQAVLKQICAQEHVLERCLKNAEQLC---DMIIDEMLTAKQAQRVLHMI 1462
.|: .:|..:|.|:|:.||:.||.||.|.|.|||..|:|| ::|:|.:|:..|||::|.:|
Rat 1276 --KSI-SIETANLREYARYVLRTICQQEWVGEHCLKEPERLCTDKELILDPVLSNMQAQKLLQLI 1337
Fly 1463 CYPEPEFNIISELD--QRSMIVRILENLGQWTLRISWLDLQLMYRQSLSNN-----AELNVWLDT 1520
|||. .....:|.| ||..|.|||:||.|||||.|||:||||.:|.|.:. ||:|..||.
Rat 1338 CYPH-GIKECTEGDNLQRQHIKRILQNLEQWTLRQSWLELQLMIKQCLKDPSSGSVAEMNNLLDN 1401
Fly 1521 VARAAIDVFHMEE--------------------VVLPGAVK-------ATHKPKPSTWLVAPLIA 1558
:|:|.|:||.... .|.|.:.: .:...:...||||||||
Rat 1402 IAKATIEVFQQSADLNNNASSSGMSLFNPNTIGSVDPSSTRQNGIKTFLSSSERRGVWLVAPLIA 1466
Fly 1559 KLTPAVQGRILRVAGQVLESMNYFSKVSKSDCNSSGSGDEREKSNSCHSSNSYGLGGVPARNKKM 1623
:|..:||||:|:.||:.||...:. ||..::|:......|.|.
Rat 1467 RLPTSVQGRVLKAAGEELEKGQHL-----------GSSSKKERDRQKQKSMSL------------ 1508
Fly 1624 PLDYQPFLGLILTCLKGQDEYKENLLVSLYAQLSQCLQSFAELDTIGGIDEPQAREEILDALQLR 1688
|..||||.|:|||||||||.:|.||.||..|::|.|.::.|... .|:.:||:.:.:|||||
Rat 1509 -LSQQPFLSLVLTCLKGQDEQREGLLTSLQNQVNQILSNWREERY---QDDTKARQMMHEALQLR 1569
Fly 1689 FSLVGGMFEAIQKNSTPTTDWAILLAQLVCQGVVDLSCNRELFTTVVDMLATLVHSTLVSD---- 1749
.:||||||:.:|:::..|||||:||.|::..|.||:..|.||||||:|||..|::.||.||
Rat 1570 LNLVGGMFDTVQRSTQGTTDWALLLLQIITSGTVDMHTNNELFTTVLDMLGVLINGTLASDLSTA 1634
Fly 1750 -------DERHYMNLMKKLKKEIGEKNNASIRVIRQLLPLYKQPTEVIACEHSG--MDTKGNKIC 1805
::|.||||:||||||:|:|.:.||..:||||||.||..:||.||..| :|||||||.
Rat 1635 SPGGSEENKRAYMNLVKKLKKELGDKRSESIDKVRQLLPLPKQTCDVITCEPMGSLIDTKGNKIA 1699
Fly 1806 ---DIDKKQ-LRISDKQRISVWDILEGHKNPAPLSWVWFGAVKLERKPLTYEEAHRNLKYHTHSL 1866
.||||| |::|.||::|.||:.||.||||||||.|||.|:::|:.:.|||.|..|.||||::
Rat 1700 GFDSIDKKQGLQVSTKQKVSPWDLFEGQKNPAPLSWAWFGTVRVDRRVIKYEEQHHFLLYHTHTM 1764
Fly 1867 VKPSSYYYEPLPLPPEDIEPVPEKICIKDEMKADTPSSVDQSP---SAVVGGTGRGRG---KGTT 1925
.||.|||.||||||||:.|..| .|.|.|.| ||.:...|:... |.|.
Rat 1765 PKPRSYYLEPLPLPPEEEEEEP-------------TSPVSQEPERKSAELSDHGKSAADEEKKTK 1816
Fly 1926 TRKRKPKN----------------PKTPPVVNTQQQQPQ-------LAQQPQQP----QN----- 1958
.||||.|: |...|:.:......| |..||||| ||
Rat 1817 GRKRKTKSSSRIDEYQQTNIYRLPPNYSPMSSQMMHHTQPALWGYNLVSQPQQPSFFLQNQSLNA 1881
Fly 1959 ---------------------------------------------------VQQQQLQQQQQQQQ 1972
:||||.||||||||
Rat 1882 GGSRLDPAGSFVPTNTKQALSNMLQRRSGAMLQPPSLHAVTSQQQLLQMKLLQQQQQQQQQQQQQ 1946
Fly 1973 HMQQQHMQQQQMQPNQMGQMPMNMPMNMQQFAPNPNNMMQQNAMLQQQQQQQMQ-------QMGN 2030
..||:.::|.|.:|.|.||......:...|..|:| .:.|...||||.|...| ||
Rat 1947 QQQQRLLRQAQTRPFQQGQPGDQAALFTAQARPSP--QLPQYPGLQQQAQTMPQGYTMYGTQM-- 2007
Fly 2031 NPMQQQLNVGGGNGQPNPQMNFMQQGPGGGGAGPQGMPGQQQQWHNAP-------QQQQPPQPYH 2088
|:||. .||.|||....|..........|::| |.||.|..|.
Rat 2008 -PLQQA----------------AQQQPGGVVLSPSYSSRAYPAAHSSPALMERLRQLQQQPGGYV 2055
Fly 2089 NQYA-PHQQNMQSNRIERPPLNANSKQALSQMLRQRQPFQQQAQQGP--GGGFN----------- 2139
.|.| |:.|.: |.||.|. .|..||.| ||..:
Rat 2056 QQQASPYLQPV----------------AGSQRLN-----HQALQQSPLVGGAIDAVLTPAHPNLP 2099
Fly 2140 --PMQQQP-QASQQQPGPQQQMNPNQMRQQQMNPQQ--NPQSVA-AFNAMQ-QQP-------QQN 2190
|:.|.| :..|||...||::...|..||...||| .|||.| ...||| ||| ||.
Rat 2100 SVPLAQDPMRPRQQQVRQQQRLLQMQQPQQAPQPQQPSQPQSQALGLQAMQPQQPLFPRQGLQQT 2164
Fly 2191 AQQQQMNPNQQQQQQFMRGGNMRPGMAP 2218
.||||.....:|.|:.:.....:.|:.|
Rat 2165 QQQQQTAALVRQLQKQLSSNQPQQGVTP 2192
| 
