DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment abo and DET1

DIOPT Version :9

Sequence 1:	NP_524784.1	Gene:	abo / 44793	FlyBaseID:	FBgn0000018	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_192756.2	Gene:	DET1 / 826609	AraportID:	AT4G10180	Length:	543	Species:	Arabidopsis thaliana

Alignment Length:	564	Identity:	130/564 - (23%)
Similarity:	236/564 - (41%)	Gaps:	126/564 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RLFYKCITPCLTIDSITIPPIYLRKFTPDGRKLLAFSQDQRSLLI-------YSYGGSSCAAVGE 97
            |.||:.:.|..|:..:..|....||||.||..|::||::.:.|::       ||....|...:..
plant    29 RHFYENLVPSYTLYDVESPDHCFRKFTEDGLFLISFSRNHQELIVYRPSWLTYSTTDDSTTTLPP 93

  Fly    98 LIRQADVGSGECFSSQDTILKSRIFERLFPTKETLNLCQG------DFGLYYLHREFSVFLEEGR 156
            |.|:|..                 |:..|....::||...      ||.||:..|.|.:|
plant    94 LPRRASK-----------------FDSFFTQLYSVNLASSNELICKDFFLYHQTRRFGLF----- 136

  Fly   157 YAMLAAMTVVRGALPVDDYVRYPDLFDKVDAFSYVFFLVDLKLGVVTDRLILPNDSIVIAHNHGI 221
              ..:...:...:.|.:|.|......||:     .|.|:.|..|||.|..:..:|.:.:|||.|:
plant   137 --ATSTAQIHDSSSPSNDAVPGVPSIDKI-----TFVLLRLDDGVVLDERVFLHDFVNLAHNMGV 194

  Fly   222 SVFGSTVMMMSRLHQCVYVYWVNDG--------------------------------KFHQQETI 254
            .::...:.::|..:|.:::..:.|.                                |..||...
plant   195 FLYDDLLAILSLRYQRIHLLQIRDSGHLVDARAIGYFCREDDELFLNSSSQAMMSQDKSKQQSLS 259

  Fly   255 GPRPRDFIEKATTDFDNLDATTVLP------ITHIKQRVLSFLYRKI-NDKSGNPTESQ---KSF 309
            |.:..|      |..:.|..:...|      ::.:|||:|||::|:| |::|.|....|   |.|
plant   260 GSKEDD------TGENGLRHSLSQPSGSNSFLSGVKQRLLSFIFREIWNEESDNVMRVQSLKKKF 318

  Fly   310 YKNFEYIEHMIMERMHLVNNELLMLRYEERPNG----TDTMPMATSPRRLYVFYTITGEEVVGVY 370
            |.:|:....:|:.::..::.:.|::::.....|    .|..|      ..:..|.:...::|..|
plant   319 YFHFQDYVDLIIWKVQFLDRQHLLIKFGSVDGGVTRSADHHP------AFFAVYNMETTDIVAFY 377

  Fly   371 PEYSVNLLQILLQFNDYMSNDRSLQFGDAPSLPMHFFLRHTFADSNESVSVD--RHTALRFNP-- 431
            ...:.:|.|:..||:|:.:...|..|       |:|...|    ||...:::  ::|..:.|.
plant   378 QNSAEDLYQLFEQFSDHFTVSSSTPF-------MNFVTSH----SNNVYALEQLKYTKNKSNSFS 431

  Fly   432 --------SVPLSSQSLSSSPYLKFNEFRYDSRYVSPLEQPHRCCNDPIVFLD-RATDSIKFRLH 487
                    |:|.|.||.|.|||...:.||:|.:.:|..::..:..::||.|:. |...::||::.
plant   432 QFVKKMLLSLPFSCQSQSPSPYFDQSLFRFDEKLISAADRHRQSSDNPIKFISRRQPQTLKFKIK 496

  Fly   488 ATARRHLNPLAPRELCAFIWHPFDPLVLSIQKC--MNSYVYHVH 529
            ............:::|:|::||..||.:|||:.  |...|.::|
plant   497 PGPECGTADGRSKKICSFLFHPHLPLAISIQQTLFMPPSVVNIH 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abo	NP_524784.1	Det1	146..531	CDD:286780	100/445 (22%)
DET1	NP_192756.2	Det1	122..542	CDD:286780	104/454 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2275
eggNOG	1	0.900	-	-		E1_KOG2558
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I1941
OMA	1	1.010	-	-		QHG60266
OrthoDB	1	1.010	-	-		D603320at2759
OrthoFinder	1	1.000	-	-		FOG0007100
OrthoInspector	1	1.000	-	-		oto3028
orthoMCL	1	0.900	-	-		OOG6_105528
Panther	1	1.100	-	-	LDO	PTHR13374
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840