Protein Alignment Adk3 and Adk

DIOPT Version :10

• Sequence 1: NP_651995.1
• Gene: Adk3 / 44750
• FlyBaseID: FBgn0026602
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_598840.1
• Gene: Adk / 11534
• MGIID: 87930
• Length: 361
• Species: Mus musculus
• Alignment Length: 342
• Identity: 92/342 - (26%)
• Similarity: 154/342 - (45%)
• Gaps: 25/342 - (7%)

  Fly    35 GNVLLDRLVQLEDPQLLERFGLELGSKGELDMEKLNQLAAEASESSRCLTNPGGSALNTARILKQ 99
            ||.||| :..:.|...|:::.|:...: .|..:|..:|..|..:..:...:.|||..|:.::.:.
Mouse    29 GNPLLD-ISAVVDKDFLDKYSLKPNDQ-ILAEDKHKELFDELVKKFKVEYHAGGSTQNSMKVAQW 91

  Fly   100 LGTD----ALFFGAVGADKHAEELRQIIRDRGIEARLQTVEDAHTGQCVCLMYQDNPTLYANIGA 160
            |..:    |.|||.:|.||..|.|::...|..::|......:..||.|...:...|.:|.||:.|
Mouse    92 LIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYYEQNEQPTGTCAACITGGNRSLVANLAA 156

  Fly   161 SAQFEVQTLSHAVSHEGQSFLRPVERKQILYVEGFFVPQRSDVCDYIVQHLVRERRRLALNLSAP 225
            :..::.:  .| :..|....|  ||:.::.|:.|||:....:....:.::.....|...||||||
Mouse   157 ANCYKKE--KH-LDLERNWVL--VEKARVYYIAGFFLTVSPESVLKVARYAAENNRVFTLNLSAP 216

  Fly   226 YIVRKNHQAMMKLARAAFFLFGNRQEFEALAEAAG-GFRNVDELADHL-----LQSGGTKVIFVT 284
            :|.:...:|:|.:......||||..|....|...| ..:::.|:|...     :.|...:.:..|
Mouse   217 FISQFFKEALMDVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFT 281

  Fly   285 NGSAGVQVITNYVEELAPPGPVSFEDFRAQRVEQLVDATGAGDAFVAGFLHAWLEKRSLGECIRM 349
            .|.....|        |....|:......|..|:::|..|||||||.|||...:..:.|.||||.
Mouse   282 QGRDDTIV--------AAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRA 338

  Fly   350 ASSVAAKVVTQVGCNLP 366
            ....|:.::.:.||..|
Mouse   339 GHYAASVIIRRTGCTFP 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adk3	NP_651995.1	adenosine_kinase	28..366	CDD:238573	91/340 (27%)
Adk	NP_598840.1	Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:P55263	7..15
		ribokinase_pfkB_like	28..360	CDD:469648	92/342 (27%)