Protein Alignment Cnx99A and canx

DIOPT Version :10

• Sequence 1: NP_477157.1
• Gene: Cnx99A / 44643
• FlyBaseID: FBgn0015622
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001005668.1
• Gene: canx / 448161
• XenbaseID: XB-GENE-5735140
• Length: 606
• Species: Xenopus tropicalis
• Alignment Length: 581
• Identity: 295/581 - (50%)
• Similarity: 377/581 - (64%)
• Gaps: 28/581 - (4%)

  Fly    31 DLDTESDDFEDGYVEDVQEEPAVIGGDEKLAYESPVIDAKKFHFADHFDDVEESRKRWVLSQAKK 95
            |:|.|.:|.|:...|.....||     .|:.|::|| ...:.:|::.||  :.:...|:||:|||
 Frog    48 DIDDELEDPEELKPETSTPPPA-----PKVTYKAPV-PTGEVYFSESFD--KGTLDGWILSKAKK 104

  Fly    96 DDIAEEISKYDGIWNWESPQRIVWANDLGLVLKSKAKHAAIAAPLRKPFEFKSDKPLVVQYEVTL 160
            ||..|||:||||.|.....:......||||||.|:|||.|||:.::|||.| ..|.|:|||||..
 Frog   105 DDTDEEIAKYDGKWEVLEMKDTKLPGDLGLVLMSRAKHHAIASKMKKPFVF-DKKSLIVQYEVNF 168

  Fly   161 QEGQECGGSYLKLLSAGKDTEQL-KAFNDKTPYTIMFGPDKCGNDVKMHFIFRHVNPINGTITEK 224
            |.|.||||:|:||||  |..||. :.|:|||||||||||||||.|.|:||||||.||..|...||
 Frog   169 QNGIECGGAYVKLLS--KTPEQKPEQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGEYEEK 231

  Fly   225 HCNKPKNRLEEPFKDKLPHLYQLVVRPDNSFEIRVDHKIINEGSLLTDFKPPVNPPAEIDDPNDH 289
            |..:|...|:..|.||..|||.||:.|||||||.||..::|.|:||.|..||||||.||:||.|.
 Frog   232 HAKRPDADLKSYFTDKKTHLYTLVLNPDNSFEILVDQTVVNRGNLLNDVNPPVNPPNEIEDPEDK 296

  Fly   290 KPESWDEREKIPDPTAHKPEDWDEDAPPQLPDTDAVMPNGWLEDEPDMIFDPTATKPEDWDAEID 354
            |||.||||.|||||.|.||:|||||||.::||.:||.|.|||:|||:.|.||.|.||||||.::|
 Frog   297 KPEDWDERPKIPDPDAVKPDDWDEDAPAKIPDENAVKPEGWLDDEPEYIPDPDAEKPEDWDEDMD 361

  Fly   355 GEWEAPLVDNPVCEKAPGCGKWKAPLIPNPNYKGKWRAPMIENPNYQGKWAPRKIPNPDFFEDLK 419
            ||||||.|.||.||.|||||.|:.|.|.||:|||||:.|||:||||||.|.|||||||||||||:
 Frog   362 GEWEAPQVANPKCESAPGCGVWQRPTIDNPSYKGKWKPPMIDNPNYQGIWKPRKIPNPDFFEDLE 426

  Fly   420 PFQMTPISAVGLELWSMSSDILFDNLIITDDVEVARDFAANSFDIKRRYIDRESDSFVNKVVELA 484
            ||:|||..|||||||||:|||.|||.|:|.:..||.|:|.:.:.:|:......:.|.|.:::..|
 Frog   427 PFRMTPFYAVGLELWSMTSDIFFDNFIVTSEKNVADDWANDGWGLKKAADGASAPSVVGQMMAAA 491

  Fly   485 KANPSIWGIGLVAIVALVALTI-YCRFGTAKSQDSAAKKAAAEAKKSDDPQPD-DEPEAEEESDE 547
            :..|.:|.:.::.:...|.|.| :|..|..:..|       ||.||:|.|||| .|.|.|:|.:|
 Frog   492 EERPWLWIVYILTVALPVFLVILFCCSGKKQPLD-------AEHKKTDAPQPDVKEEEEEDEEEE 549

  Fly   548 RAAGDTSKESTPLSASPKKNQKSDLDDNEEESKAAESREPAQTEES---NTKTRKRQARKE 605
            ..|....:|.....:.||:::..|.:..|||    |:.|..:|:|.   |...|.|:.|::
 Frog   550 GKANKIEEEEDAEESEPKQDEAEDQESQEEE----EAEEEIKTKEDDIINRSPRNRKPRRD 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cnx99A	NP_477157.1	Calreticulin	74..447	CDD:459737	235/373 (63%)
canx	NP_001005668.1	Calreticulin	85..454	CDD:459737	235/373 (63%)