Protein Alignment Cnx99A and cnx1

DIOPT Version :10

• Sequence 1: NP_477157.1
• Gene: Cnx99A / 44643
• FlyBaseID: FBgn0015622
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_001342872.1
• Gene: cnx1 / 2543041
• PomBaseID: SPAC3C7.11C
• Length: 560
• Species: Schizosaccharomyces pombe
• Alignment Length: 621
• Identity: 220/621 - (35%)
• Similarity: 318/621 - (51%)
• Gaps: 108/621 - (17%)

  Fly     9 RAATLALLFASSLLLLSAANAADLDTESDDFEDGYVEDVQEEPAVIGGDEKLAYESPVIDAKKFH 73
            :.:.||||.:    |....:.||.::|             :||.|....|   .::|:::..:..
pombe     5 KVSFLALLCS----LYVRGSLADPESE-------------QEPLVFNPTE---VKAPLVEQFQGA 49

  Fly    74 FADHFDDVEESRKRWVLSQAKKDDIAEEISKYDGIWNWE---SPQRIVWANDLGLVLKSKAKHAA 135
            :::          ||:.|.||:.....|...|.|.|..|   .|..:  ..:.|||:|.:|.|.|
pombe    50 WSE----------RWIPSHAKRFVNGIEEMSYVGEWTVEESSGPGAL--KGEAGLVMKDEAAHHA 102

  Fly   136 IAAPLRKPFEFKSDKPLVVQYEVTLQEGQECGGSYLKLLSAGKDTEQLKAFNDKTPYTIMFGPDK 200
            |:....:|.. :.:|.|||||||..:||..|||:|||||:.....|    .::...|.|||||||
pombe   103 ISYEFDEPIN-EPEKDLVVQYEVNPEEGLNCGGAYLKLLAEPTHGE----MSNSIDYRIMFGPDK 162

  Fly   201 CGNDVKMHFIFRHVNPINGTITEKHC-NKPKNRLEEPFKDKLPHLYQLVVRPDNSFEIRVDHKII 264
            ||.:.::||||:|.||:.|..:|||. ::|.:.|    |..:.:||.|:|:||.:||:|::..::
pombe   163 CGVNDRVHFIFKHKNPLTGEYSEKHLDSRPASLL----KPGITNLYTLIVKPDQTFEVRINGDVV 223

  Fly   265 NEGSLLTDFKPPVNPPAEIDDPNDHKPESWDEREKIPDPTAHKPEDWDEDAPPQLPDTDAVMPNG 329
            .:|||..||.|||.||.||.||.|.||..|.:..:||||.|.||:|||||||..:||.|||.|..
pombe   224 RQGSLFYDFIPPVLPPVEIYDPEDIKPADWVDEPEIPDPNAVKPDDWDEDAPRMIPDPDAVKPED 288

  Fly   330 WLEDEPDMIFDPTATKPEDWDAEIDGEWEAPLVDNPVCEKAPGCGKWKAPLIPNPNYKGKWRAPM 394
            ||||||..|.||.|.||||||.|.||:|....:.||.|.:..|||:||.|:|.||||:|.|..||
pombe   289 WLEDEPLYIPDPEAQKPEDWDDEEDGDWIPSEIINPKCIEGAGCGEWKPPMIRNPNYRGPWSPPM 353

  Fly   395 IENPNYQGKWAPRKIPNPDFFEDLKPFQMTPISAVGLELWSMSSDILFDNLIITDDVEVARDFAA 459
            |.||.:.|:|.||||||||:|:|..|....|:..||.|||:|..:|.|.|:.:...:|.|.....
pombe   354 IPNPEFIGEWYPRKIPNPDYFDDDHPSHFGPLYGVGFELWTMQPNIRFSNIYVGHSIEDAERLGN 418

  Fly   460 NSF-----------------DIKRRYIDRESDSFVNKVVEL-----AKANPSI------------ 490
            .:|                 :.:..::|.||:..:.|.:::     ||..|::
pombe   419 ETFLPKLKAERELLSKQESMEKQSMHVDEESNQILEKFLDVYDIIKAKLPPNVAEKVDYYVETII 483

  Fly   491 ----WGIGLVAIV-ALVALTIYCRFGTAKSQDSAAKKAAAEAKKSDDPQPDDEPEAEEESDERAA 550
                .||.:||:: :|.|:.:.|.|....|...|:.....             .|||:|..|:..
pombe   484 ETPEIGIAIVAVLGSLTAVILTCYFYFFASSSPASLSTGT-------------TEAEKEQQEKFK 535

  Fly   551 GDTSKESTPLSASPKKNQKSDLDDNEEESKAAESRE 586
            .:|..|...:|.:|           |.||..|::.:
pombe   536 QETETEKIDVSYAP-----------ETESPTAKNED 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cnx99A	NP_477157.1	Calreticulin	74..447	CDD:459737	174/376 (46%)
cnx1	NP_001342872.1	Calreticulin	42..406	CDD:459737	174/384 (45%)