Protein Alignment Cnx99A and crt-1

DIOPT Version :10

• Sequence 1: NP_477157.1
• Gene: Cnx99A / 44643
• FlyBaseID: FBgn0015622
• Length: 605
• Species: Drosophila melanogaster
• Sequence 2: NP_504575.1
• Gene: crt-1 / 178997
• WormBaseID: WBGene00000802
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 168/491 - (34%)
• Similarity: 239/491 - (48%)
• Gaps: 117/491 - (23%)

  Fly    66 VIDAKKFHFADHFDDVEESRKRWVLSQAKKDDIAEEISK---YDGIWNWESPQRIVWANDLGLVL 127
            |:.| :.:|.:.|:|. ...||||.|:.|.|..|.::|.   :|           |.:.|.|:..
 Worm    12 VVSA-EVYFKEEFNDA-SWEKRWVQSKHKDDFGAFKLSAGKFFD-----------VESRDQGIQT 63

  Fly   128 KSKAKHAAIAAPLRKPFEFKSDKPLVVQYEVTLQEGQECGGSYLKLLSAGKDTEQLKAFNDKTPY 192
            ...||..:.||...|.|..|. |.||:||.|..::|.:|||.|:|::.|..|   |..|:.:|||
 Worm    64 SQDAKFYSRAAKFDKDFSNKG-KTLVIQYTVKHEQGIDCGGGYVKVMRADAD---LGDFHGETPY 124

  Fly   193 TIMFGPDKCGNDVKMHFIFRHVNPINGTITEKHCNKPKNRL---EEPFK-DKLPHLYQLVVRPDN 253
            .:|||||.||...::|.|..:              |.:|:|   |...| |:|.|||.|::..||
 Worm   125 NVMFGPDICGPTRRVHVILNY--------------KGENKLIKKEITCKSDELTHLYTLILNSDN 175

  Fly   254 SFEIRVDHKIINEGSLLTDFKPPVNPPAEIDDPNDHKPESWDEREKIPDPTAHKPEDWDEDAPPQ 318
            ::|:::|.:....|||..|:  .:.|..:|.||:..|||.|||||.|.|....|||||
 Worm   176 TYEVKIDGESAQTGSLEEDW--DLLPAKKIKDPDAKKPEDWDEREYIDDAEDAKPEDW------- 231

  Fly   319 LPDTDAVMPNGWLEDEPDMIFDPTATKPEDWDAEIDGEWEAPLVDNPVCEKAPGCGKWKAPLIPN 383
                          ::|:.|.||.|.||||||.|:|||||.|::|                   |
 Worm   232 --------------EKPEHIPDPDAKKPEDWDDEMDGEWEPPMID-------------------N 263

  Fly   384 PNYKGKWRAPMIENPNYQGKWAPRKIPNPDFFEDLKPFQMTPISAVGLELWSMSSDILFDNLIIT 448
            |.|||:|:...|:||.|:|||...:|.||::..|.:.:......|:|.:||.:.|..:|||:|||
 Worm   264 PEYKGEWKPKQIKNPAYKGKWIHPEIENPEYTPDDELYSYESWGAIGFDLWQVKSGTIFDNIIIT 328

  Fly   449 DDVEVARDFAANSFDIKRRYIDRESDSFVNKVVELAKANPSIWGIGLVAIVALVALTIYCRFGTA 513
            |.||.|...||.:|| |.:.:::|...         ||:..                      |.
 Worm   329 DSVEEAEAHAAETFD-KLKTVEKEKKE---------KADEE----------------------TR 361

  Fly   514 KSQDSAAKKA--AAEAKKSDDPQPDDEPEAEEESDE 547
            |:::.|.|||  ..||||.||   ::|.|.||..||
 Worm   362 KAEEEARKKAEEEKEAKKDDD---EEEKEEEEGHDE 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cnx99A	NP_477157.1	Calreticulin	74..447	CDD:459737	133/379 (35%)
crt-1	NP_504575.1	Calreticulin	19..327	CDD:459737	133/379 (35%)