Protein Alignment Smyd3 and smyd4

DIOPT Version :9

• Sequence 1: NP_524768.2
• Gene: Smyd3 / 44554
• FlyBaseID: FBgn0011566
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001070062.1
• Gene: smyd4 / 767654
• ZFINID: ZDB-GENE-060929-248
• Length: 753
• Species: Danio rerio
• Alignment Length: 595
• Identity: 126/595 - (21%)
• Similarity: 206/595 - (34%)
• Gaps: 197/595 - (33%)

  Fly     5 TVGSSRSATTSATASACSSKSKNL----KNPAPQIKRGQRILTEKPFAFVL-------------K 52
            ||.|:...:...:....|.|.:::    ..||     |:.:|.::.:..||             .
Zfish   177 TVNSTGHLSDGVSVYFSSDKGRHMLVMENKPA-----GEVVLEDEAYCSVLIPANIFNTGTNKAV 236

  Fly    53 SQYRLE--RCDNCL-EATKVLKCSNCRYVSYCHRSCQMQAWGQ-HKHECPFLKKVHPRVVPD--A 111
            ..:..|  .|.:|| ::...:.|..|.|..||..|||..||.| |:.|||        |..|  |
Zfish   237 ETFGTEDRHCHHCLSQSLSFVPCPKCSYARYCGESCQKDAWDQWHQWECP--------VGADLLA 293

  Fly   112 ARMLCRLILRLEHGGDLIRGYYTE--HGSRKFRDLMSHYAEIKND-PMR----------LEHLDS 163
            ..:|..|.||:     :::...||  .|.:..:|   |....||| |::          |:|.|.
Zfish   294 IGVLGHLALRV-----VLKAGQTEVQMGIKNTKD---HVTTYKNDSPVQLSLGGDCGKSLDHTDC 350

  Fly   164 LH--------AVLTDMMAESPST-------------------VPNK-------------TELMSI 188
            .|        ::|..:...||::                   .|||             ...||:
Zfish   351 FHGSSYMGIYSLLPHVAQHSPASRFLMAITMAVIYGKLQGGPPPNKWMSFKDEGVKASWQPEMSM 415

  Fly   189 YG--------------RLIT-------NGFNILDAEMNSIATAIYLGVSITDHSCQPNAVATF-- 230
            .|              :.||       :|..:..:....|||||:..:|:.:|||.||...:|
Zfish   416 LGATALRHMMQLRCNAQAITAVRVKEESGMAVQSSSEIRIATAIFPVLSLLNHSCSPNTSISFTT 480

  Fly   231 -------------EGNELH-----------VHAIEDMECLDWSKIFISYIDLLNTPEQRRLDLK- 270
                         ||:..|           |.|.:|:..  ..:|...|     .|.:.|:::|
Zfish   481 GFQPDPHNQLGCSEGHFDHPKGSRSGVTVTVRASKDLTA--GQEILHCY-----GPHRSRMEVKE 538

  Fly   271 ------EHYYFLCVCSKC-TDAKE----SKEMLAA------------------LCPNRNCGAGIS 306
                  |.|:|.|||..| .|..|    :||..|.                  .|...:||..||
Zfish   539 RQRLLLEQYFFQCVCQACQRDLSEGSPNAKEHTAPGMKCVKCGKPLQSHTDGYTCSWSSCGHQIS 603

  Fly   307 VDRNNCPRCDAGISPKLRN---AFNEAMTLTRHNLENMKDVAYLDVCKVCLDKQTGVFHPLNVWY 368
                     .|.:..:|:.   ..:||:    |.:|..:....|.:.:....:...:....:.:.
Zfish   604 ---------SADVQNRLQGFQLLLDEAV----HLMEQDRLNEALHILQSAFSQANSILTETHPFQ 655

  Fly   369 VKTLDAAFEAAIEVGKWSDALDYGQRLLPGFRKYHGPWNPLLGLLHMKLGKIQLYEGHSKEALHH 433
            .:..||........|:||.|..:.:|.|...:...|..:..||....||.::.........:|..
Zfish   656 GELADALARLYASTGEWSLAASHLKRSLVAIQAQFGEDSIELGRQLFKLAQLHFNGRDGVASLSV 720

  Fly   434 LEEAQRILTV 443
            :..|:|:|::
Zfish   721 IPRARRLLSL 730

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	zf-MYND	60..97	CDD:280009	15/38 (39%)
		TPR_12	377..440	CDD:290160	13/62 (21%)
smyd4	NP_001070062.1	TPR_11	68..134	CDD:290150
		TPR repeat	68..96	CDD:276809
		TPR repeat	101..134	CDD:276809
		zf-MYND	246..285	CDD:280009	15/38 (39%)
		SET	<456..532	CDD:214614	20/82 (24%)
		T6SS_VasJ	<603..679	CDD:299836	14/88 (16%)
		TPR_12	615..683	CDD:290160	12/71 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582734
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740