Protein Alignment Smyd3 and smyd2a

DIOPT Version :10

• Sequence 1: NP_524768.2
• Gene: Smyd3 / 44554
• FlyBaseID: FBgn0011566
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_001013568.1
• Gene: smyd2a / 541423
• ZFINID: ZDB-GENE-050320-126
• Length: 435
• Species: Danio rerio
• Alignment Length: 448
• Identity: 109/448 - (24%)
• Similarity: 203/448 - (45%)
• Gaps: 55/448 - (12%)

  Fly    24 KSKNLKNPAPQIKRGQRILTEKPFAFVLKSQYRLERCDNCLEATKVL-KCSNCRYVSYCHRSCQM 87
            |.:.|| .....|.|..:.....:|:||....|..||:.|....:.| ||..|:...||:..||.
Zfish    17 KGRGLK-AIKHFKVGDLVFACPAYAYVLTVNERGGRCECCFTRKEGLSKCGKCKQAYYCNVECQR 80

  Fly    88 QAWGQHKHECPFLKKVHPRVVP-DAARMLCRLILRLEHGGDLIRGYYTEHGSRK----FRDLMSH 147
            ..|..||.||..:........| :..|::.|:||:.:|        .||....:    .|:|.:|
Zfish    81 GDWPMHKLECSAMCAYGENWCPSETVRLVARIILKQKH--------QTERTPSERVLTLRELEAH 137

  Fly   148 YAEIKNDPMRLEHLD--SLHAVLTDMMAESPSTVPNKTELMSIYGRLITNGFNILDAEMNSIATA 210
            ..::.|:...:...|  :||...:..:     ..|:...|..:..::..|||.|.|.|::.:.:|
Zfish   138 LDKLDNEKNEMNDTDIAALHHFYSRHL-----DFPDNAALTELIAQVNCNGFTIEDEELSHLGSA 197

  Fly   211 IYLGVSITDHSCQPNAVATFEGNELHVHAIEDMECLDWSKIFISYIDLLNTPEQRRLDLKEHYYF 275
            ::..|::.:|||.||.:.|::|....|.|::::.  ...:||.||||||...|.|...||:.|:|
Zfish   198 LFPDVALMNHSCSPNVIVTYKGTVAEVRAVQEIN--PEEEIFNSYIDLLYPTEDRIERLKDSYFF 260

  Fly   276 LCVCSKCTDAKESKEMLAALCPNRNCGAGISVDRNNCPRCDAGISPKLRNAFNEAMTLTRHNLEN 340
            .|.|.:||...:.:..:..                   |....|.|: .....:.:...|:.:|.
Zfish   261 NCDCKECTSKSKDEAKMEI-------------------RQKLSIPPE-EEEIKQMVIYARNVIEE 305

  Fly   341 MKDVAY-------LDVCKVCLDKQTGVFHPLNVWYVKTLDAAFEAAIEVGKWSDALDYGQRLLPG 398
            .:...:       |::|::.::|...:|...||:.:..:..|....:.:..|..|:.||::::..
Zfish   306 FRRAKHYKTPSELLEICELSMEKMGAIFAETNVYMLHMMYQAMGVCLYMQDWDGAMKYGEKIIHP 370

  Fly   399 FRKYHGPWNPLLGLLHMKLGKIQLYEGHSK--EALHHLEEAQRILTVTHGRDHRLLTE 454
            :..::.|::..:..:::|||:  ||.|..|  :.:..|::|..|:.:.||:||..:.|
Zfish   371 YSVHYPPYSLNVASMYLKLGR--LYLGLEKRTQGVKALKKALAIMDIAHGKDHPYIDE 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	SET	34..284	CDD:394802	73/257 (28%)
		zf-MYND	60..97	CDD:460312	13/37 (35%)
		TPR_12	<383..441	CDD:315987	14/59 (24%)
smyd2a	NP_001013568.1	SET	7..269	CDD:394802	76/267 (28%)
		zf-MYND	52..90	CDD:460312	13/37 (35%)
		TPR_12	382..>424	CDD:315987	14/43 (33%)