Protein Alignment Smyd3 and Smyd4-1

DIOPT Version :10

• Sequence 1: NP_524768.2
• Gene: Smyd3 / 44554
• FlyBaseID: FBgn0011566
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Alignment Length: 470
• Identity: 113/470 - (24%)
• Similarity: 166/470 - (35%)
• Gaps: 159/470 - (33%)

  Fly    28 LKNPAPQ---------IKRGQRILTEKPFAFVLKSQYRLERCDNCLEATKV---LKCSNC-RYVS 79
            |.:|.|:         |.:|..|.:|:...||...|..:  |..| .||.:   :.|.|| :.|.
  Fly   219 LTDPGPRGRYMVAKEAISKGNVIFSERASCFVPLEQLLI--CQQC-AATLMSAPIPCPNCHQRVV 280

  Fly    80 YCHRSCQMQAWGQHKHECPFLKKVHPRVVPDAARML--CRLILRLEHGGDL------IRGYYTEH 136
            ||.|.|:......||.||...:|       |..|:|  ..|.|||     |      ||.:..|.
  Fly   281 YCSRKCREAHSAIHKFECAAYRK-------DILRLLGISHLALRL-----LLTYIPYIRPHLQEM 333

  Fly   137 GSRK-----FRDLMSHYAEIKNDPMRLEHLDSL------------------------------HA 166
            .|.|     ..:|.....|.:|.|   |:|.||                              |.
  Fly   334 TSAKGMWEEIMNLSRKPEESENAP---EYLRSLRMVSQLDQAIDEELNYHILCANLLQLYLKEHT 395

  Fly   167 VLTDMMAESPSTVPN-----KTELMSIYGRLITNG---------------FNILDAEM------- 204
            ...|.....|:::.:     ...::...|:|:.||               |.:|..|:
  Fly   396 DFYDQFHSLPASIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQPELWQKPRHL 460

  Fly   205 ----------NSIATAIYLG-VSITDHSCQPNAVATFEGNELHVHAIEDMECLDWSKIFISY-ID 257
                      :...|||.|. :|:.:|:|:|:....|:|..:..:|.:|:  |:..:||..| :|
  Fly   461 KRGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNYAAKDI--LEGEEIFNCYTMD 523

  Fly   258 LLNTPE-QRRLDLKEHYYFLCVCSKCTDAKESKEMLAALCPNRNCGAGISVDRNNC--PRCDAGI 319
            ..|:.: ||...||..|.|.|.|:|||...          |::|.   :|..|..|  |.|....
  Fly   524 YRNSLKLQRSHPLKAIYKFECTCAKCTRTD----------PDQNY---LSFHRYRCEKPNCRQEF 575

  Fly   320 SPKLRNAFNEAMTLTRHNLENMKDVAYLDVCKVCLDKQTGVFHPLN--VWYVKTL---------- 372
            .|..:...|......|.|.|  |.:    .|.||        |.|.  .||.:.|
  Fly   576 LPDAKVQQNNLRWWLRCNAE--KPI----TCTVC--------HELQHFAWYNEFLGLIGSSADSS 626

  Fly   373 --DAAFEAAIEVGKW 385
              .|.|:|..::.||
  Fly   627 KRQALFKAFDDLDKW 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	SET	34..284	CDD:394802	83/345 (24%)
		zf-MYND	60..97	CDD:460312	14/40 (35%)
		TPR_12	<383..441	CDD:315987	2/3 (67%)
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	9/32 (28%)
		zf-MYND	258..298	CDD:460312	14/40 (35%)
		SET	<359..549	CDD:394802	39/191 (20%)