Protein Alignment Smyd3 and SmydA-4

DIOPT Version :10

• Sequence 1: NP_524768.2
• Gene: Smyd3 / 44554
• FlyBaseID: FBgn0011566
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_572675.1
• Gene: SmydA-4 / 32034
• FlyBaseID: FBgn0030257
• Length: 532
• Species: Drosophila melanogaster
• Alignment Length: 489
• Identity: 102/489 - (20%)
• Similarity: 176/489 - (35%)
• Gaps: 128/489 - (26%)

  Fly    34 QIKRGQRILTEKPFAF-----------------VLKS-QYRLERCDNCLEATKVLKCSNCRYVSY 80
            |::.|:.::.|:|.|.                 .||: |||               |..|.: ..
  Fly    66 QLEAGETLIREEPLAIGPCVSGDPVCLGCYHPVSLKADQYR---------------CPGCAW-PL 114

  Fly    81 CHRSCQMQAWGQHKH-----ECP------------FLKKVHPRVVPDAAR--MLCRLILRLEHGG 126
            |..:|   |..:|:|     ||.            ..::..|..|.|...  |:.|::|..:|..
  Fly   115 CGSTC---AGLKHRHGHTETECQLYAERRAVAGELLTERAGPAEVRDLYELVMIVRILLLRQHDP 176

  Fly   127 D---LIRGY--YTEHGSRKFRDLMSHYAEIKNDPMRLEHLDSLHAVLTDMMAESPSTVPNKTELM 186
            :   ||...  :||. .|:...|..||.|.....:|:..      .|.|:.||         ::.
  Fly   177 EQFALIARMESHTEE-RRQNAVLWRHYEEKVVQRLRVTW------QLEDLEAE---------QVH 225

  Fly   187 SIYGRLITNGFNILDAEMNSIATAIYLGVSITDHSCQPNAVATFEGNELHV-----HAIEDMECL 246
            .:.|.|..|.|.|  .:..:.|..:|....:..|.|.||...|.:.:...:     ..:.:.|.|
  Fly   226 EVCGILDVNCFEI--GQNGAKARTLYPSAFLLAHDCTPNTAHTDDPSSFEILLRTSRRVREREAL 288

  Fly   247 DWSKIFISYIDLLNTPEQRRLDLKEHYYFLCVCSKCTDAKE-SKEMLAALCPNRNCGAGISVDRN 310
            .     :||...|....:||..:.|...|.|.|.:|:|.:| ..:..|.:|.....|:..:||..
  Fly   289 T-----LSYAYTLQGTLKRRAFMHEGKLFWCCCRRCSDPRELGTDCSALVCATCRTGSVRAVDPL 348

  Fly   311 N------CPRC-----DAGISPKLRNAFNEAMTLTRHNLENMKD--VAYLDV------------- 349
            .      |.||     ...:..:|....|:...:..|::..:::  :.|.||
  Fly   349 QQTGDWACDRCAHKMGATEVERQLDRINNDLEDIDVHDIPGLENFLLRYRDVLRPNHYLLLSAKY 413

  Fly   350 --CKVCLDKQTGVFHP-LNVWYVKTLDAAFEAAIEVGKWSDALDYGQRLLPGFRKY--HGPWNPL 409
              |:: ..:..|...| ::...:...::.....:|:   .|.||.|...|.|...|  |.| ..:
  Fly   414 SLCQI-YGRTEGYLLPQMSPEDIARKESYCREFLEI---VDVLDPGLTRLRGLIMYELHAP-VMV 473

  Fly   410 LGLLHMKLGKI--QLYEGHSKEALHHLEEAQRIL 441
            |.....:.|:|  |.::...||.:..|:.::.||
  Fly   474 LAQSAFQSGQISRQEFQRRLKEVVKLLQVSRDIL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	SET	34..284	CDD:394802	64/296 (22%)
		zf-MYND	60..97	CDD:460312	7/41 (17%)
		TPR_12	<383..441	CDD:315987	16/61 (26%)
SmydA-4	NP_572675.1	SET_SMYD	<230..319	CDD:380997	22/95 (23%)