Protein Alignment Smyd3 and SmydA-3

DIOPT Version :10

• Sequence 1: NP_524768.2
• Gene: Smyd3 / 44554
• FlyBaseID: FBgn0011566
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_061512667.1
• Gene: SmydA-3 / 1278184
• VectorBaseID: AGAMI1_000512
• Length: 500
• Species: Anopheles gambiae
• Alignment Length: 488
• Identity: 108/488 - (22%)
• Similarity: 169/488 - (34%)
• Gaps: 124/488 - (25%)

  Fly    32 APQIKRGQRILTEKPFAFVLKSQYRLERCDNCLEATKVL-------KCSNCRYVSYCHRSCQMQA 89
            |..:|.|:.:..|.|||...|    |:....|||....:       :||.|.: ..| ..|  .|
Mosquito    21 ARDLKAGELLFEETPFAVGPK----LDSPPLCLECCCPVDGGEGGPRCSRCGW-PLC-EDC--SA 77

  Fly    90 WG----QHKHECPFL--KKVHPRVVPDA----ARMLC----RLILRLEHGGDLIRGYYTEHGSRK 140
            .|    .|:.||...  ..|..|.|.|:    .::.|    |::|..|  .|..|      ..|:
Mosquito    78 GGAELVYHRGECEVFAANGVRFRPVEDSTAGCVQLDCITPLRVLLAKE--ADEAR------WKRE 134

  Fly   141 FRDLMSHYAEIKNDPMRLEHLDSLHAVLTDMMAESPSTVPNKTELMSIYGRLITNGFNILDAEMN 205
            ...:..|.||.:.........:::.|.|     ..|..:..:     ....|:.....:||....
Mosquito   135 IEPMEYHDAERREGANWKVDENNIVAFL-----RGPCGLGKR-----FSAELVQRAIGLLDVNAF 189

  Fly   206 SIAT-------AIYLGVSITDHSCQPNAVATFE-GNELHVHAIEDMECLDWSKIFISYIDLLNTP 262
            ...|       .:|..::|..|:|.||.|.:.. .|...:.|...::..:..|::.:|...|...
Mosquito   190 EGRTGSGYSCRGLYPQLAIMAHNCVPNVVHSIHPSNGFRMVARVAVDVREGDKLYTTYTYTLTGT 254

  Fly   263 EQRRLDLKEHYYFLCVCSKCTDAKE-SKEMLAALCPNRNCGAGI-----SVDRN---NCPRC--- 315
            ..|:..||...:|.|.|::|.|..| .......||  ..|..|:     .:|.|   .|.:|
Mosquito   255 VARQSILKASKFFTCRCTRCLDPTELGTHFSTLLC--SKCSGGLITSTDPLDENAEWKCGQCGFK 317

  Fly   316 --DAGISPKLRNAFNEAMTLTRHNLENMKDVAYLDVCKVCLDKQTGVFHPLNVWYVKTLDAAFEA 378
              .|.:...:....||...|.....|..:..||..|.|    |...|.|||:  ::.|  :...:
Mosquito   318 TSGAAVQKAVMTIHNEIDELACFEYEAGRLEAYETVYK----KYRSVLHPLH--FINT--SIRHS 374

  Fly   379 AIEVGKWSDALDYGQRLLPGFRKYHGP----------WNPLLGLLHM-KLGKIQ-----LYEGHS 427
            .||:        ||:  :||:.....|          ...:|.:|.: :.||.:     |||.|:
Mosquito   375 LIEL--------YGR--IPGYEMAELPDVLLERKVELCRSILRVLDVFEPGKSRARAMILYELHA 429

  Fly   428 -------------------KEALHHLEEAQRIL 441
                               |.....|.||.:||
Mosquito   430 PLIMLAQSAFARGEDQRDGKSLKQQLNEAAQIL 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	SET	34..284	CDD:394802	61/278 (22%)
		zf-MYND	60..97	CDD:460312	11/47 (23%)
		TPR_12	<383..441	CDD:315987	17/92 (18%)
SmydA-3	XP_061512667.1	None