Protein Alignment Smyd3 and SmydA-2

DIOPT Version :10

• Sequence 1: NP_524768.2
• Gene: Smyd3 / 44554
• FlyBaseID: FBgn0011566
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_309220.6
• Gene: SmydA-2 / 1270515
• VectorBaseID: AGAMI1_014742
• Length: 519
• Species: Anopheles gambiae
• Alignment Length: 502
• Identity: 103/502 - (20%)
• Similarity: 162/502 - (32%)
• Gaps: 155/502 - (30%)

  Fly    60 CDNCLEATKVLKCSNCRYVSYCHRSCQMQAW-GQHKHECPFLKKV-------------------- 103
            |..| .|..:.:|:.|:.|.||.|..|...| .||:.:|...|.|
Mosquito     6 CRVC-SAPAMQRCAGCQQVGYCGRDHQRADWKAQHRDQCRRFKVVRNDRLGRHLVATRHIKQGEI 69

  Fly   104 ----HPRVV-PDAARM-LCRLILRLEHGGDLIRGYYTEHGSRKF---------------RDLMSH 147
                .|..| |..|.: ||     |....:|:.|:....|..:|               .::..|
Mosquito    70 IYRDEPYAVGPKIANVPLC-----LGCNRNLMAGWDATRGLDRFHECSRCGWPLCGPGCEEVAQH 129

  Fly   148 YAE------------IKNDPMRLEHLDSLHAVLT-------------------------DMMAES 175
            ..|            |:.:|...|..:|.:.|:.                         |....|
Mosquito   130 RPECSVLAGSGYRPNIRPNPSNPEQRESAYCVIVPLRVLLLERIAPERYATVQGFESHLDERLAS 194

  Fly   176 P-------STVP-----------NKTELMSIYGRLITNGFNILDAEMNSIATAIY-LGVSITDHS 221
            |       :.||           ::..::.:...|.||.:.|...|.:.....:| ||..:: |.
Mosquito   195 PLYGVLRSNLVPFLRQVLRLQQYSEQTVLKLSAILDTNCYEIRLPEQHVKVRGLYPLGAMLS-HD 258

  Fly   222 CQPNAVATFEGNELHVHAIEDMECLDWSKIFISYIDLLNTPEQRRLDLKEHYYFLCVCSKCTDAK 286
            |:||....|: :.||:..:..::......|..||...|....||||.|::...|.|.|.:|.|..
Mosquito   259 CRPNTKHYFD-DRLHMVLVATVDIPAGGVIHASYTQPLLGTVQRRLALRQAKCFDCCCERCADPT 322

  Fly   287 ESKEMLAAL-CPN--RNCGAGISVDRNN------CP--RCDAGISPKLRNAFNEAMTLTRHNLEN 340
            |.....:.. |||  |.....::|:..|      |.  ||.....|....|..|.|......|:.
Mosquito   323 EYGTSASGFRCPNCRRTPSLVLAVEPTNYRTVWRCQNRRCAYQERPDQYVARCERMQQELLALDR 387

  Fly   341 MKDVAYLDVCKVCLDKQTGVFHPLNVWYVKT------------------LDAAFEAAIEVGKWSD 387
            .:...|.:.    |.:.....||.|.:.::.                  .:||....:|:.:  |
Mosquito   388 TEPAGYEEF----LARHATTLHPWNAYMLQAKYALTQLLGSARPAKAPPSEAAARRTVELCR--D 446

  Fly   388 ALDYGQRLLPGFRKYHGPWNPLLGLLHMKLGKIQLYEGHSKEALHHL 434
            .|...:||.||:..:.              .|:.|..|.:...||.|
Mosquito   447 LLAVAERLEPGYSTFR--------------AKLLLELGSALATLHAL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	SET	34..284	CDD:394802	67/321 (21%)
		zf-MYND	60..97	CDD:460312	13/37 (35%)
		TPR_12	<383..441	CDD:315987	12/52 (23%)
SmydA-2	XP_309220.6	None