Protein Alignment Smyd3 and SmydA-4

DIOPT Version :10

• Sequence 1: NP_524768.2
• Gene: Smyd3 / 44554
• FlyBaseID: FBgn0011566
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_061514871.1
• Gene: SmydA-4 / 1268645
• VectorBaseID: AGAMI1_003090
• Length: 528
• Species: Anopheles gambiae
• Alignment Length: 497
• Identity: 114/497 - (22%)
• Similarity: 177/497 - (35%)
• Gaps: 127/497 - (25%)

  Fly    32 APQIKRGQRILTEKPFAFVLKSQYRLER-CDNCLEATK----VLKCSNCRYVSYCHRSCQ-MQAW 90
            |..:|.|..|:...|  ||:......|. |..|..|.|    |.:|..|.: ..|..||. :...
Mosquito    62 ARDLKAGDVIIETPP--FVVGPCAETEPVCLGCHNAFKPGSVVYRCEICNW-RICSPSCHGLAPA 123

  Fly    91 GQHKH-EC-PFLKKV---HPRVVPDA-ARMLCRLILRLEHGGDLIRGYYTEHGSRKFRDLMSHYA 149
            |.|:. || |...|.   |.:..|.| .:::...||.|       |....:...|...|
Mosquito   124 GTHRQLECIPLRDKAVHKHLQTSPTAQVKLMYEAILTL-------RCMLLKTVDRPQYD------ 175

  Fly   150 EIKNDPMRLEHLDSLHAVLTDM-------MAESPSTVPN--------KTELMSIYGRLITNGFNI 199
                   ||..:|.|:.|...:       ..|....:.|        :.||.:|.|.:..|.|.:
Mosquito   176 -------RLLGMDPLNDVRQQIPKLWNRNQKEIVERIRNQWGFAEYSELELHTICGIIEVNAFEV 233

  Fly   200 LDAEMNSIATAIYLGVSITDHSCQPNAVATF--EGNELHVHAIEDMECLDWSKIFISYIDLLNTP 262
              .:..:.|.|::....:..|.|.||...|.  :.:.|.|..:.|::.  ...:.::|..:|...
Mosquito   234 --GQEPTKARALFPEAYLLMHDCTPNTGHTDAPQTHHLTVRVLRDVKA--GEPLTLTYAHILQGT 294

  Fly   263 EQRRLDLKEHYYFLCVCSKCTDAKESKEMLAAL----CPNRNCGAGISVDRNN------CPRCDA 317
            .:||..|:|..:|.|.|.:|||..|.....:||    ||.   |..:..|..|      |.:|..
Mosquito   295 LKRRQHLREEKFFSCNCRRCTDPSELGTNCSALRCKKCPR---GHILPTDPLNPETEWHCRQCST 356

  Fly   318 GISPKLRNAFNEAMTLTRHNL-ENMKDVAYLDV--CKVCLDKQTGVFHPLNVWYVKTLDAAFEAA 379
            .:|       .||:.|....| :.::.:...||  .:..|..|..|.|..:...:....:..|.
Mosquito   357 VMS-------CEAVILLLEQLSQQLETIGGNDVDGLETFLRVQGAVLHDNHYLLLSVKHSLCEL- 413

  Fly   380 IEVGK--------------------WSDALDYGQRLLPGFRKYHGPWNPLLGLLHMKL----GKI 420
              .||                    ..|.|:...:|.||..:..|   .::..:|:.|    |
Mosquito   414 --YGKIEGFLIPQLSREQLKRKETLCRDLLEVVDQLEPGLSRLRG---TIMYEMHVPLLIEAG-- 471

  Fly   421 QLYEG----------HSKEALHHLEEAQRIL------TVTHG 446
            ||::|          ..||....|:|::|||      |..||
Mosquito   472 QLFQGGVIQRAELRRRLKEVQRLLKESERILALEPEGTPEHG 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	SET	34..284	CDD:394802	65/278 (23%)
		zf-MYND	60..97	CDD:460312	12/42 (29%)
		TPR_12	<383..441	CDD:315987	19/91 (21%)
SmydA-4	XP_061514871.1	None