Protein Alignment Smyd3 and smyd2

DIOPT Version :10

• Sequence 1: NP_524768.2
• Gene: Smyd3 / 44554
• FlyBaseID: FBgn0011566
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: XP_002934751.2
• Gene: smyd2 / 100495522
• XenbaseID: XB-GENE-985583
• Length: 430
• Species: Xenopus tropicalis
• Alignment Length: 448
• Identity: 111/448 - (24%)
• Similarity: 209/448 - (46%)
• Gaps: 56/448 - (12%)

  Fly    24 KSKNLKNPAPQIKRGQRILTEKPFAFVLKSQYRLERCDNCLEATKVL-KCSNCRYVSYCHRSCQM 87
            |.:.||...| ...|:.:.:...:.:||....|...|:.|....:.| ||..|:...||:..||.
 Frog    15 KGRGLKATRP-FALGELLFSCPAYTYVLTVNERGNHCEFCFARKEGLSKCGKCKQAFYCNVDCQK 78

  Fly    88 QAWGQHKHECPFLKKVHPRVVP-DAARMLCRLILRLEHGGDLIRGYYTEH-GSRKF---RDLMSH 147
            ..|..||.||..:........| :..|:..|::.:        :...||. .|.:|   :|..||
 Frog    79 GDWPMHKLECSAMCTYGQNWCPSETVRLTARILAK--------QKTQTERTASERFLSVKDFESH 135

  Fly   148 YAEIKNDPMRLEHLD--SLHAVLTDMMAESPSTVPNKTELMSIYGRLITNGFNILDAEMNSIATA 210
            .:::.|:.:.|...|  :||...:..:..|.:...     :.::.::..|||.|.|.|::.:.:|
 Frog   136 LSKLDNEKLELIQNDIAALHRFYSKNLHYSDNAAQ-----VFLFAQVNCNGFTIEDEELSHLGSA 195

  Fly   211 IYLGVSITDHSCQPNAVATFEGNELHVHAIEDMECLDWSKIFISYIDLLNTPEQRRLDLKEHYYF 275
            |:..|::.:|||.||.:.|::|....|.|::::...|  ::|.||||||...|.|...|.:.|:|
 Frog   196 IFPDVALMNHSCCPNVIVTYKGTVAEVRAVQEIHAGD--EVFTSYIDLLYPTEDRNDRLIDSYFF 258

  Fly   276 LCVCSKCTDAKESKEMLAALCPNRNCGAGISVDRNNCPRCDAGISPKLRNAFNEAMTLTRHNLEN 340
            .|.|.:|:..::..             |.:.:.:.:.|.     ||::   ..:.:...|:.:|.
 Frog   259 NCDCRECSTKQKDP-------------AKLEIRKLSDPP-----SPQV---VRDMIKYARNVVEE 302

  Fly   341 MKDVAY-------LDVCKVCLDKQTGVFHPLNVWYVKTLDAAFEAAIEVGKWSDALDYGQRLLPG 398
            .:...:       |::|::.|:|...||...||:.:..:..|....:.:..|..||.||::::..
 Frog   303 FRRAKHYKTPSELLEICELSLEKMGSVFEDSNVYMLHMMYQAMGVCLYMQDWEGALKYGEKIIKP 367

  Fly   399 FRKYHGPWNPLLGLLHMKLGKIQLYEGHSKEAL--HHLEEAQRILTVTHGRDHRLLTE 454
            :.|::.|::..:..:.:|||:  ||.|..|:|:  ..|::|..|:.:.||.||..:.|
 Frog   368 YSKHYPPYSLNVASMWLKLGR--LYMGLEKKAIGTKALKKAIAIMDIAHGPDHHYIAE 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd3	NP_524768.2	SET	34..284	CDD:394802	69/257 (27%)
		zf-MYND	60..97	CDD:460312	13/37 (35%)
		TPR_12	<383..441	CDD:315987	17/59 (29%)
smyd2	XP_002934751.2	SET_SMYD2	5..267	CDD:380979	73/267 (27%)
		zf-MYND	50..88	CDD:460312	13/37 (35%)