Protein Alignment Hnf4 and rxrg

DIOPT Version :10

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_004913829.2
• Gene: rxrg / 779621
• XenbaseID: XB-GENE-478493
• Length: 535
• Species: Xenopus tropicalis
• Alignment Length: 460
• Identity: 161/460 - (35%)
• Similarity: 237/460 - (51%)
• Gaps: 87/460 - (18%)

  Fly   101 NSSNQSSENFALCNG----NGNAGSAGGGSASSGSNNNNSMFSPNNNLS------GSGSGTNS-- 153
            ::|..||.|.|..|.    .|..|::..|..|. :.|.||:.||.||:.      .|..|.:|
 Frog    91 STSVSSSSNLAAMNSLDVHTGYMGNSMNGPRSM-TTNMNSLCSPGNNIGPPYRVIASSMGPHSLP 154

  Fly   154 SQQQLQQQQQQQSP----------------------------------------TVCAICGDRAT 178
            |...|.....:..|                                        .:|||||||::
 Frog   155 SPTILNFPGHESPPFNLMNNISCSEDIKPPPGLSNLGSPCMNNYSCNSPGALTKHICAICGDRSS 219

  Fly   179 GKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRNQCRYCRLRKCFKAGMKKEAVQNE 243
            |||||..||:||||||:|::||:..||||..::|::||.:||:|:|||.:||...|||:||||.|
 Frog   220 GKHYGVYSCEGCKGFFKRTIRKDLVYTCRDTKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEE 284

  Fly   244 RDRISCRRTSNDDPDPGNGLSVISLVKAENESRQS---------KAGAAMEPNI----NEDLSNK 295
            |.|      |.:..|          .:||:.|..|         :|..|:||.|    :..|.|.
 Frog   285 RQR------SREKSD----------TEAESTSSTSEEMPVERILEAELAVEPKIEAFGDAGLPNS 333

  Fly   296 QFASINDVCESMKQQLLTLVEWAKQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLL 360
            ....:.::|.:..:||.|||||||:||.|::|.|:|||.||||...|.|:...|.||:.::|.:|
 Frog   334 TNDPVTNICHAADKQLFTLVEWAKRIPHFSDLPLEDQVILLRAGWNELLIASFSHRSVSVQDGIL 398

  Fly   361 LSNNCVITRHCPDPLVSPNLDISRIGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNE 425
            |:....:.|..     :.|..:..|..|::.|||:.|||:.:|.:|..|::|:|.|:|:||||:.
 Frog   399 LATGLHVHRSS-----AHNAGVGSIFDRVLTELVSKMKDMEMDKSELGCLRAIVLFNPDAKGLSN 458

  Fly   426 PHRIKSLRHQILNNLEDYISDRQYESRGRFGEILLILPVLQSITWQMIEQIQFAKIFGVAHIDSL 490
            ...:::||.::...||.|...:..|..|||.::||.||.|:||..:.:|.:.|.|:.|...||:.
 Frog   459 AAEVEALREKVYATLESYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTF 523

  Fly   491 LQEML 495
            |.|||
 Frog   524 LMEML 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	46/74 (62%)
		NR_LBD_HNF4_like	264..494	CDD:132729	85/242 (35%)
rxrg	XP_004913829.2	Nuc_recep-AF1	99..206	CDD:463363	20/107 (19%)
		NR_DBD_RXR	209..285	CDD:143514	45/75 (60%)
		NR_LBD_RXR_like	305..513	CDD:132741	76/212 (36%)