Protein Alignment Hnf4 and nhr-147

DIOPT Version :10

• Sequence 1: NP_723413.1
• Gene: Hnf4 / 44544
• FlyBaseID: FBgn0004914
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_504873.2
• Gene: nhr-147 / 182170
• WormBaseID: WBGene00015395
• Length: 373
• Species: Caenorhabditis elegans
• Alignment Length: 353
• Identity: 85/353 - (24%)
• Similarity: 139/353 - (39%)
• Gaps: 74/353 - (20%)

  Fly   166 SPTVCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHQYTCRFARNCVVDKDKRN---QCRYCRL 227
            :|..|::||..|.|.||...||.|||.||||......:..|....:|...|:|..   :||.||.
 Worm    10 TPITCSVCGRSAKGYHYDVISCKGCKTFFRRMYLLKSKIICGLNNSCFDLKNKNEPYLRCRACRY 74

  Fly   228 RKCFKAGMKKEAVQN-----------------------------ER-----DRISCRRTSNDDPD 258
            :||...||.:..:|:                             ||     .::...|||:.:|.
 Worm    75 KKCIDVGMNRNGIQSSESKKEFNKTQKLNFQVMESADDVMNSIIERLSYVESKLEIFRTSSFNPQ 139

  Fly   259 PGNGLSVISLVKAENESRQSKAGAAMEPNINEDLSNKQFASINDVCESMKQ-----QLLTLVEWA 318
                .|..|.:|...|.....:......|..|.:....|.:.|...::.|:     .|||:.|:.
 Worm   140 ----WSSFSSLKYLLEGTCQLSSTEKSENGLEKIYIIDFPTGNQYTKTNKKIWTLCNLLTITEYI 200

  Fly   319 KQIPAFNELQLDDQVALLRAHAGEHLLLGLSRRSMHLKDVLLLSNNCVITRHC-----PDPLVSP 378
            |....|:::..:|::.|.|     |::|...         :|..::..::|..     ||.....
 Worm   201 KTFECFHKISSNDRLVLTR-----HIILMCK---------ILHESHYAVSRKFDNYLNPDGTQES 251

  Fly   379 NLDISR-IGARIIDELVTVMKDVGIDDTEFACIKALVFFDPNAKGLNEPHRIKSL---RHQILNN 439
            ..::.. :.|..|..||.    ..|...|:..:||:.|.:|...||:: |...:|   |.|..|.
 Worm   252 KTEMHHSLLAMSISPLVR----THIQPVEYVLLKAMCFCNPAVTGLSQ-HAQTTLAKERQQFGNL 311

  Fly   440 LEDYISDRQYESRGRFGEILLILPVLQS 467
            |.|.....:.:..|.|.|::.||.:|::
 Worm   312 LFDLCRKNRRDGPGHFVELVGILGLLEN 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hnf4	NP_723413.1	NR_DBD_HNF4A	170..245	CDD:143518	31/111 (28%)
		NR_LBD_HNF4_like	264..494	CDD:132729	49/218 (22%)
nhr-147	NP_504873.2	ZnF_C4	13..85	CDD:197701	28/71 (39%)
		HOLI	192..340	CDD:214658	40/167 (24%)