Protein Alignment CG2841 and GRB7

DIOPT Version :9

• Sequence 1: NP_001284821.1
• Gene: CG2841 / 44529
• FlyBaseID: FBgn0003159
• Length: 1239
• Species: Drosophila melanogaster
• Sequence 2: NP_001229371.2
• Gene: GRB7 / 2886
• HGNCID: 4567
• Length: 555
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 70/414 - (16%)
• Similarity: 118/414 - (28%)
• Gaps: 127/414 - (30%)

  Fly   293 GSKSPDEDSTDGHY--------ATLDLKPPIAGGPEPTPRKRLLQIKKKTAPAPPPDFQSGGDNI 349
            |...|.:..|.|..        ..|||.||
Human     2 GKWRPGQGHTTGSVKPLSCSDAMELDLSPP----------------------------------- 31

  Fly   350 SLASLPEPVTPTPNIPQPAPR-ITTPLP---------IAPTANPPLAQVNGNGNGSPNGNVSKVL 404
            .|:|.||.:.|.|..|...|| ..||||         :.||....|.:........|:
Human    32 HLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPS------- 89

  Fly   405 LNRTPTPEPRSLGSATEDDDNDTASKQADSGIGEPAPSPSVSP---EPEAEKSQQESSSEDDEAI 466
               .|.|.|                        |....||.||   .|.:.:......:.....:
Human    90 ---IPNPFP------------------------ELCSPPSQSPILGGPSSARGLLPRDASRPHVV 127

  Fly   467 KVYNFK-LCQTSKKPEPSAAT-LAELTALTAQDIEEE-------------DNHVDQPASITNGNL 516
            |||:.. .|::.:....:.|. :.|:....|..:.:|             :..::...|:.....
Human   128 KVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQA 192

  Fly   517 ATPSSETSLTSWNYLDPISPPPDFSDQQMQKRNAGSLSPGSPLDEIVDELATIINQQRLDTLIKK 581
            |.|....|...:.        .:|:..::.|.:..||.|...:...:|....|.::..:...:..
Human   193 AWPVGGDSRFVFR--------KNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNA 249

  Fly   582 QPDPQM---VEIESAKPNRLANF--------SITTAKSTTRIGRADSFQAGASGGGTEVASSGRA 635
            ...|::   :::..:.......|        ...:.|.|::..|...:.|..:.....|.:.||.
Human   250 GSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRK 314

  Fly   636 LSHRSSSH---VSLNKLEQNGIGL 656
            |....:..   |..|||.....||
Human   315 LYGMPTDFGFCVKPNKLRNGHKGL 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2841	NP_001284821.1	Ehrlichia_rpt	372..958	CDD:118064	52/326 (16%)
GRB7	NP_001229371.2	RA_GRB7	123..210	CDD:340557	13/94 (14%)
		PH_APBB1IP	248..370	CDD:269961	16/91 (18%)
		BPS	389..433	CDD:401046
		SH2_Grb7	448..555	CDD:198276

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3751
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900