Protein Alignment Bem46 and ABHD12B

DIOPT Version :10

• Sequence 1: NP_477372.1
• Gene: Bem46 / 44441
• FlyBaseID: FBgn0025109
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_001193602.1
• Gene: ABHD12B / 145447
• HGNCID: 19837
• Length: 362
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 74/291 - (25%)
• Similarity: 123/291 - (42%)
• Gaps: 57/291 - (19%)

  Fly    48 IFYYAQDLLLYHPDLPANSRIYIPIPTMHNLPH-ITVSIKTPDDVTLHAFWVTQPEERSK----- 106
            :|....|:|:|.....|...:.:..|.: .:|| :...::....|.| ..|.|.|..|.:
Human    64 VFLPLIDMLIYFNFFKAPFLVDLKKPEL-KIPHTVNFYLRVEPGVML-GIWHTVPSCRGEDAKGK 126

  Fly   107 -----------SSPTLLYFHGNAGN--MGHRMQNVW----GIYHHLHCNVLMVEYRGYGLSTGVP 154
                       .:|.::|.||:|.:  ..||::.|.    |.:|     ||.|:|||:|.|||.|
Human   127 DCCWYEAALRDGNPIIVYLHGSAEHRAASHRLKLVKVLSDGGFH-----VLSVDYRGFGDSTGKP 186

  Fly   155 TERGLVTDARAAIDYLHTRHDLDHSQLILFGRSLGGAVVVDVAADTVYGQK---LMCAIVENTFS 216
            ||.||.|||....::...|..:  :.:.|:|.|||..|..:.|  .|..:|   :...::|..|:
Human   187 TEEGLTTDAICVYEWTKARSGI--TPVCLWGHSLGTGVATNAA--KVLEEKGCPVDAIVLEAPFT 247

  Fly   217 SIPEMAVELVHPAVKYIPNL----------LFKNK--YHSMSKIGKCSVPFLFISGLADNLVPPR 269
            ::  ....:.:|.:|...|:          |.|:|  :.:...:...|.|.|.:.|..|..||..
Human   248 NM--WVASINYPLLKIYRNIPGFLRTLMDALRKDKIIFPNDENVKFLSSPLLILHGEDDRTVPLE 310

  Fly   270 MMRALYT------KCGSEIKRLLEFPGGSHN 294
            ..:.||.      :....:|.::..||..||
Human   311 YGKKLYEIARNAYRNKERVKMVIFPPGFQHN 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bem46	NP_477372.1	FrsA	73..312	CDD:440691	69/266 (26%)
ABHD12B	NP_001193602.1	PTZ00360	<78..>169	CDD:240379	19/92 (21%)
		FrsA	130..343	CDD:440691	60/223 (27%)