DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mEFTu1 and RABE1b

DIOPT Version :9

Sequence 1:	NP_001163144.1	Gene:	mEFTu1 / 44438	FlyBaseID:	FBgn0024556	Length:	489	Species:	Drosophila melanogaster
Sequence 2:	NP_001329775.1	Gene:	RABE1b / 827784	AraportID:	AT4G20360	Length:	476	Species:	Arabidopsis thaliana

Alignment Length:	487	Identity:	236/487 - (48%)
Similarity:	320/487 - (65%)	Gaps:	45/487 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AAAVCRSTA-----------SMSLALRCSRRAMS---SARMLRMAGATATSTACKDWQRNGLLAA 56
            |.|.|.|::           |:..|:..|.:..:   |:..|.....|.|| |.:..:|:..:.|
plant     5 APAACSSSSRILCSYSSPSPSLCPAISTSGKLKTLTLSSSFLPSYSLTTTS-ASQSTRRSFTVRA 68

  Fly    57 PRTGNMQQYLREYANEKKVFERTKPHCNVGTIGHVDHGKTTLTAAITKVLADKQLAESKKYNEID 121
            .| |.              |||.|||.|:||||||||||||||||:|..||....:.:|||:|||
plant    69 AR-GK--------------FERKKPHVNIGTIGHVDHGKTTLTAALTMALASIGSSVAKKYDEID 118

  Fly   122 NAPEEKARGITINVAHVEYQTETRHYGHTDCPGHADYIKNMITGTAQMDGAILVVAATDGAMPQT 186
            .||||:|||||||.|.|||:||.|||.|.||||||||:||||||.||||||||||:..||.||||
plant   119 AAPEERARGITINTATVEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSGADGPMPQT 183

  Fly   187 REHMLLAKQIGIDHIVVFINKVDAADE-EMVDLVEMEIRELLTEMGYDGDKIPVVKGSALCALE- 249
            :||:|||||:|:..:|||:||.|..|: |:::|||:|:||||:...::||.||::.||||.|:|
plant   184 KEHILLAKQVGVPDMVVFLNKEDQVDDAELLELVELEVRELLSSYEFNGDDIPIISGSALLAVET 248

  Fly   250 -DKSPEIGK------EAILKLLQEVDSFIPTPVRELDKPFLLPVENVYSIPGRGTVVTGRLERGV 307
             .::|::.:      :.|.:|:..||.:||.|.|:.:.||||.||:|:||.|||||.|||:|||.
plant   249 LTENPKVKRGDNKWVDKIYELMDAVDDYIPIPQRQTELPFLLAVEDVFSITGRGTVATGRVERGT 313

  Fly   308 VKKGMECEFVGYNKVLKSTVTGVEMFHQILEEAQAGDQLGALVRGVKRDDIKRGMVMCKPGSVKA 372
            ||.|...:.||..:....||||||||.:||:||.|||.:|.|:||:::.||:||||:.||||:..
plant   314 VKVGETVDLVGLRETRSYTVTGVEMFQKILDEALAGDNVGLLLRGIQKADIQRGMVLAKPGSITP 378

  Fly   373 LDQLEAQVYILSKDEGGRTKPFMSFIQLQMFSRTWDCAVQVQ--IPDKE----MVMPGEDTKLIL 431
            ..:.||.:|:|.|:||||..||.:..:.|.:.||.|...:|.  :.||:    |||||:..|:::
plant   379 HTKFEAIIYVLKKEEGGRHSPFFAGYRPQFYMRTTDVTGKVTKIMNDKDEESKMVMPGDRVKIVV 443

  Fly   432 RLIRPMVLEQGQRFTLRDGNLTLGTGVVTSTL 463
            .||.|:..|||.||.:|:|..|:|.||:.:.|
plant   444 ELIVPVACEQGMRFAIREGGKTVGAGVIGTIL 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFTu1	NP_001163144.1	PRK00049	73..463	CDD:234596	218/404 (54%)
		EF_Tu	81..274	CDD:206671	120/201 (60%)
		EFTU_II	282..368	CDD:293898	50/85 (59%)
		mtEFTU_III	371..462	CDD:294005	38/96 (40%)
RABE1b	NP_001329775.1	PLN03126	17..476	CDD:215592	232/475 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	265	1.000	Domainoid score	I461
eggNOG	1	0.900	-	-		E1_COG0050
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	473	1.000	Inparanoid score	I347
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491836at2759
OrthoFinder	1	1.000	-	-		FOG0002097
OrthoInspector	1	1.000	-	-		mtm1013
orthoMCL	1	0.900	-	-		OOG6_100780
Panther	1	1.100	-	-	O	PTHR43721
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2038
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.830